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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of TORC1 signaling
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Accession:GO:1903432 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of TORC1 signaling.
Synonyms:exact_synonym: regulation of TORC1 signal transduction


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regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G C9orf72 C9orf72-SMCR8 complex subunit IMP (PMID:27559131) UniProtKB PMID:27559131 NCBI chr 9:27,546,546...27,573,866
Ensembl chr 9:27,535,640...27,573,866
JBrowse link
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 IEA InterPro GO_REF:0000002 NCBI chr22:30,285,117...30,289,505
Ensembl chr22:30,285,117...30,289,627
Ensembl chr22:30,285,117...30,289,627
JBrowse link
G DGKQ diacylglycerol kinase theta IMP (PMID:23767959) ParkinsonsUK-UCL PMID:23767959 NCBI chr 4:958,887...973,569
Ensembl chr 4:958,887...986,895
JBrowse link
G DYRK3 dual specificity tyrosine phosphorylation regulated kinase 3 IMP (PMID:23415227) UniProtKB PMID:23415227 NCBI chr 1:206,635,536...206,655,158
Ensembl chr 1:206,635,536...206,684,419
JBrowse link
G RRAGC Ras related GTP binding C IMP (PMID:27222292) UniProtKB PMID:27222292 NCBI chr 1:38,838,198...38,859,772
Ensembl chr 1:38,838,198...38,859,772
JBrowse link
G SMCR8 SMCR8-C9orf72 complex subunit IMP (PMID:27559131) UniProtKB PMID:27559131 NCBI chr17:18,315,293...18,328,056
Ensembl chr17:18,315,293...18,328,056
JBrowse link
negative regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AC004997.1 novel protein IBA (PMID:21873635) GO_Central PMID:21873635 Ensembl chr22:30,285,238...30,299,482 JBrowse link
G ALG13 ALG13 UDP-N-acetylglucosaminyltransferase subunit ISO (MGI:MGI:6306805|PMID:30872163) MGI PMID:30872163 MGI:MGI:6306805 NCBI chr  X:111,680,741...111,764,164
Ensembl chr  X:111,665,811...111,760,649
JBrowse link
G ATM ATM serine/threonine kinase IMP
IBA
(PMID:23878245)
(PMID:21873635)
ParkinsonsUK-UCL
GO_Central
PMID:21873635, PMID:23878245 NCBI chr11:108,222,484...108,369,102
Ensembl chr11:108,222,832...108,369,102
Ensembl chr11:108,222,832...108,369,102
JBrowse link
G BMT2 base methyltransferase of 25S rRNA 2 homolog IDA (PMID:29123071) UniProtKB PMID:29123071 NCBI chr 7:112,819,147...112,939,875
Ensembl chr 7:112,819,147...112,939,875
JBrowse link
G C12orf66 chromosome 12 open reading frame 66 IMP
IBA
(PMID:28199306)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:28199306 NCBI chr12:64,186,316...64,222,296
Ensembl chr12:64,186,316...64,222,296
JBrowse link
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 IMP
IBA
(PMID:26972053)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:26972053 NCBI chr22:30,285,117...30,289,505
Ensembl chr22:30,285,117...30,289,627
Ensembl chr22:30,285,117...30,289,627
JBrowse link
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 IMP
IBA
(PMID:26972053)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:26972053 NCBI chr 7:74,964,693...75,031,531
Ensembl chr 7:74,964,705...75,031,528
JBrowse link
G CASTOR3 CASTOR family member 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 7:100,200,653...100,272,232
Ensembl chr 7:100,200,653...100,272,218
Ensembl chr 7:100,200,653...100,272,218
JBrowse link
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit IMP (PMID:25457612), (PMID:29769719) UniProtKB PMID:25457612, PMID:29769719 NCBI chr22:31,753,968...31,908,033
Ensembl chr22:31,753,867...31,908,033
JBrowse link
G FNIP1 folliculin interacting protein 1 ISO (MGI:MGI:5635927|PMID:25775561) MGI PMID:25775561 MGI:MGI:5635927 NCBI chr 5:131,641,714...131,797,017
Ensembl chr 5:131,641,714...131,797,063
JBrowse link
G FNIP2 folliculin interacting protein 2 ISO (MGI:MGI:5635927|PMID:25775561) MGI PMID:25775561 MGI:MGI:5635927 NCBI chr 4:158,769,026...158,908,050
Ensembl chr 4:158,769,026...158,908,050
JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 IMP (PMID:28199306) UniProtKB PMID:28199306 NCBI chr12:2,812,644...2,859,907
Ensembl chr12:2,812,622...2,859,791
JBrowse link
G KPTN kaptin, actin binding protein IMP
IBA
(PMID:28199306)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:28199306 NCBI chr19:47,475,141...47,486,792
Ensembl chr19:47,475,150...47,484,265
JBrowse link
G RNF152 ring finger protein 152 IEA
IMP
(PMID:25936802) InterPro
UniProtKB
PMID:25936802 GO_REF:0000002 NCBI chr18:61,808,067...61,894,420
Ensembl chr18:61,808,067...61,894,247
JBrowse link
G SESN1 sestrin 1 IMP
IBA
(PMID:18692468), (PMID:25263562)
(PMID:21873635)
UniProtKB
GO_Central
PMID:18692468, PMID:21873635, PMID:25263562 NCBI chr 6:108,984,309...109,094,846
Ensembl chr 6:108,986,437...109,094,819
JBrowse link
G SESN2 sestrin 2 IMP
IBA
(PMID:18692468), (PMID:24947615), (PMID:25263562), (PMID:25457612), (PMID:26449471), (PMID:26586190), (PMID:26612684)
(PMID:21873635)
UniProtKB
GO_Central
PMID:18692468, PMID:21873635, PMID:24947615, PMID:25263562, PMID:25457612, PMID:26449471, PMID:26586190, PMID:26612684 NCBI chr 1:28,259,452...28,282,491
Ensembl chr 1:28,259,518...28,282,491
JBrowse link
G SESN3 sestrin 3 IMP
IBA
(PMID:25263562)
(PMID:21873635)
UniProtKB
GO_Central
PMID:21873635, PMID:25263562 NCBI chr11:95,165,513...95,232,536
Ensembl chr11:95,165,513...95,232,541
JBrowse link
G SPAAR small regulatory polypeptide of amino acid response IMP (PMID:28024296) UniProtKB PMID:28024296 NCBI chr 9:35,909,490...35,911,686
Ensembl chr 9:35,909,490...35,937,153
JBrowse link
G STK11 serine/threonine kinase 11 IMP (PMID:23878245) ParkinsonsUK-UCL PMID:23878245 NCBI chr19:1,205,778...1,228,431
Ensembl chr19:1,177,558...1,228,431
Ensembl chr19:1,177,558...1,228,431
JBrowse link
G SZT2 SZT2 subunit of KICSTOR complex IMP (PMID:28199306), (PMID:28199315) UniProtKB PMID:28199306, PMID:28199315 NCBI chr 1:43,389,884...43,454,247
Ensembl chr 1:43,389,882...43,454,247
JBrowse link
G TSC2 TSC complex subunit 2 ISO (MGI:MGI:5509101|PMID:23878245) ParkinsonsUK-UCL PMID:23878245 MGI:MGI:5509101 NCBI chr16:2,047,804...2,089,491
Ensembl chr16:2,047,967...2,089,491
JBrowse link
positive regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CLEC16A C-type lectin domain containing 16A IMP (PMID:28223137) UniProtKB PMID:28223137 NCBI chr16:10,944,539...11,193,272
Ensembl chr16:10,944,564...11,182,186
JBrowse link
G FLCN folliculin IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr17:17,206,946...17,237,188
Ensembl chr17:17,212,212...17,237,188
JBrowse link
G GPR137 G protein-coupled receptor 137 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:64,270,337...64,289,500
Ensembl chr11:64,270,062...64,289,500
JBrowse link
G GPR137B G protein-coupled receptor 137B IMP
IBA
(PMID:31036939)
(PMID:21873635)
UniProt
GO_Central
PMID:21873635, PMID:31036939 NCBI chr 1:236,142,529...236,213,535
Ensembl chr 1:236,142,505...236,221,865
JBrowse link
G GPR137C G protein-coupled receptor 137C IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr14:52,552,836...52,637,713
Ensembl chr14:52,552,836...52,637,713
JBrowse link
G KLHL22 kelch like family member 22 IMP (PMID:29769719) UniProtKB PMID:29769719 NCBI chr22:20,441,519...20,497,305
Ensembl chr22:20,441,519...20,495,844
JBrowse link
G LAMTOR5 late endosomal/lysosomal adaptor, MAPK and MTOR activator 5 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:110,401,253...110,407,924
Ensembl chr 1:110,401,249...110,407,942
JBrowse link
G LARS1 leucyl-tRNA synthetase 1 IMP (PMID:22424946) CAFA PMID:22424946 NCBI chr 5:146,113,034...146,182,731
Ensembl chr 5:146,113,034...146,182,650
Ensembl chr 5:146,113,034...146,182,650
JBrowse link
G PIH1D1 PIH1 domain containing 1 IMP (PMID:24036451) UniProtKB PMID:24036451 NCBI chr19:49,446,298...49,452,392
Ensembl chr19:49,446,298...49,453,497
JBrowse link
G PIP4P1 phosphatidylinositol-4,5-bisphosphate 4-phosphatase 1 IMP (PMID:29644770) UniProt PMID:29644770 NCBI chr14:20,457,681...20,461,612
Ensembl chr14:20,457,681...20,461,465
Ensembl chr14:20,457,681...20,461,465
JBrowse link
G RRAGA Ras related GTP binding A IMP (PMID:25936802) UniProtKB PMID:25936802 NCBI chr 9:19,049,427...19,051,025
Ensembl chr 9:19,049,427...19,051,025
JBrowse link
G RRAGB Ras related GTP binding B IMP (PMID:22424946) CAFA PMID:22424946 NCBI chr  X:55,717,747...55,760,209
Ensembl chr  X:55,717,749...55,758,774
Ensembl chr  X:55,717,749...55,758,774
JBrowse link
G RRAGD Ras related GTP binding D IMP (PMID:22424946) CAFA PMID:22424946 NCBI chr 6:89,363,509...89,412,273
Ensembl chr 6:89,364,616...89,412,273
JBrowse link
G SEC13 SEC13 homolog, nuclear pore and COPII coat complex component IEA InterPro GO_REF:0000002 NCBI chr 3:10,300,931...10,321,112
Ensembl chr 3:10,293,131...10,321,112
JBrowse link
G SEH1L SEH1 like nucleoporin IEA
IBA
IMP
(PMID:21873635)
(PMID:25457612)
InterPro
GO_Central
UniProtKB
PMID:21873635, PMID:25457612 GO_REF:0000002 NCBI chr18:12,947,988...12,987,665
Ensembl chr18:12,947,133...12,987,536
JBrowse link
G SIK3 SIK family kinase 3 IMP (PMID:30232230) UniProt PMID:30232230 NCBI chr11:116,843,410...117,098,453
Ensembl chr11:116,843,402...117,098,437
JBrowse link
G TELO2 telomere maintenance 2 IMP (PMID:24036451) UniProtKB PMID:24036451 NCBI chr16:1,493,345...1,510,459
Ensembl chr16:1,493,344...1,510,457
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18651
    cellular process 17669
      signal transduction 6562
        intracellular signal transduction 2978
          TOR signaling 132
            regulation of TOR signaling 108
              regulation of TORC1 signaling 43
                negative regulation of TORC1 signaling 21
                positive regulation of TORC1 signaling 17
Path 2
Term Annotations click to browse term
  biological_process 18651
    biological regulation 13283
      regulation of biological process 12625
        regulation of cellular process 12021
          signal transduction 6562
            intracellular signal transduction 2978
              TOR signaling 132
                regulation of TOR signaling 108
                  regulation of TORC1 signaling 43
                    negative regulation of TORC1 signaling 21
                    positive regulation of TORC1 signaling 17
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.