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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of blood circulation
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Accession:GO:1903523 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of blood circulation.
Synonyms:exact_synonym: down regulation of blood circulation;   downregulation of blood circulation
 narrow_synonym: inhibition of blood circulation
 related_synonym: down regulation of hemolymph circulation;   downregulation of hemolymph circulation;   inhibition of hemolymph circulation;   negative regulation of hemolymph circulation


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negative regulation of blood circulation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ager advanced glycosylation end product-specific receptor JBrowse link 20 4,363,152 4,366,079 RGD:1600115
RGD:1624291
G App amyloid beta precursor protein JBrowse link 11 24,425,013 24,641,872 RGD:1624291
negative regulation of cardiac muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pde5a phosphodiesterase 5A JBrowse link 2 226,899,604 227,044,916 RGD:1624291
RGD:1600115
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115
negative regulation of heart contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adora1 adenosine A1 receptor JBrowse link 13 51,042,111 51,076,913 RGD:1625235
G Atp1a1 ATPase Na+/K+ transporting subunit alpha 1 JBrowse link 2 204,003,742 204,032,023 RGD:1624291
G Atp1a2 ATPase Na+/K+ transporting subunit alpha 2 JBrowse link 13 90,651,682 90,676,629 RGD:1624291
G Atp2a2 ATPase sarcoplasmic/endoplasmic reticulum Ca2+ transporting 2 JBrowse link 12 39,553,903 39,603,326 RGD:1624291
G Il2 interleukin 2 JBrowse link 2 123,847,150 123,851,854 RGD:727354
G Jak2 Janus kinase 2 JBrowse link 1 247,398,667 247,457,521 RGD:1641934
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:1598375
G Pde4d phosphodiesterase 4D JBrowse link 2 40,219,999 41,468,551 RGD:1624291
RGD:1600115
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
G Prkca protein kinase C, alpha JBrowse link 10 96,186,509 96,585,168 RGD:2292479
G Prkg1 protein kinase cGMP-dependent 1 JBrowse link 1 248,982,039 250,300,952 RGD:7777121
negative regulation of heart rate term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agtr2 angiotensin II receptor, type 2 JBrowse link X 119,389,480 119,393,845 RGD:1624291
G Fkbp1b FKBP prolyl isomerase 1B JBrowse link 6 29,975,863 29,987,252 RGD:1624291
G Npff neuropeptide FF-amide peptide precursor JBrowse link 7 144,127,084 144,127,873 RGD:2316573
G Pik3r1 phosphoinositide-3-kinase regulatory subunit 1 JBrowse link 2 31,742,326 31,826,882 RGD:4108483
G Pln phospholamban JBrowse link 20 34,633,157 34,642,904 RGD:1624291
G Rnls renalase, FAD-dependent amine oxidase JBrowse link 1 251,828,285 252,101,963 RGD:1624291
G Sptbn4 spectrin, beta, non-erythrocytic 4 JBrowse link 1 84,168,494 84,254,679 RGD:1624291
G Spx spexin hormone JBrowse link 4 176,629,597 176,635,698 RGD:8693358
G Sri sorcin JBrowse link 4 23,004,657 23,029,233 RGD:1624291
G Tac1 tachykinin, precursor 1 JBrowse link 4 33,638,853 33,646,819 RGD:2305984
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:14975128
G Trpv1 transient receptor potential cation channel, subfamily V, member 1 JBrowse link 10 59,799,123 59,824,208 RGD:13792700
G Uts2 urotensin 2 JBrowse link 5 168,078,748 168,084,133 RGD:2306871
negative regulation of heart rate by acetylcholine term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Chrm3 cholinergic receptor, muscarinic 3 JBrowse link 17 63,990,599 64,463,222 RGD:2303391
negative regulation of heart rate involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1a adrenoceptor alpha 1A JBrowse link 15 43,296,997 43,398,314 RGD:1624291
negative regulation of membrane repolarization during ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 JBrowse link 1 165,189,934 165,196,949 RGD:1624291
negative regulation of renin secretion into blood stream term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G F2r coagulation factor II (thrombin) receptor JBrowse link 2 26,118,760 26,135,340 RGD:1624291
RGD:1600115
negative regulation of the force of heart contraction by chemical signal term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Grk2 G protein-coupled receptor kinase 2 JBrowse link 1 219,536,220 219,544,329 RGD:1624291
RGD:1600115
negative regulation of the force of heart contraction involved in baroreceptor response to increased systemic arterial blood pressure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adra1d adrenoceptor alpha 1D JBrowse link 3 124,129,558 124,145,566 RGD:1624291
negative regulation of vascular associated smooth muscle contraction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arhgap42 Rho GTPase activating protein 42 JBrowse link 8 7,210,999 7,446,215 RGD:1624291
G Dock4 dedicator of cytokinesis 4 JBrowse link 6 60,374,839 60,782,648 RGD:1624291
G Dock5 dedicator of cytokinesis 5 JBrowse link 15 44,449,108 44,627,774 RGD:1624291
negative regulation of vasoconstriction term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Adm adrenomedullin JBrowse link 1 175,443,189 175,447,260 RGD:1624291
G Ahr aryl hydrocarbon receptor JBrowse link 6 54,963,990 55,001,806 RGD:1624291
G Apln apelin JBrowse link X 134,856,719 134,866,210 RGD:1626185
G Bmpr2 bone morphogenetic protein receptor type 2 JBrowse link 9 66,568,074 66,683,019 RGD:1624291
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:4891967
G Dusp5 dual specificity phosphatase 5 JBrowse link 1 274,245,184 274,258,595 RGD:13446412
G Hif1a hypoxia inducible factor 1 subunit alpha JBrowse link 6 96,810,868 96,856,303 RGD:5147878
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1626660
G Lep leptin JBrowse link 4 56,337,695 56,351,818 RGD:5128573
G Mmp2 matrix metallopeptidase 2 JBrowse link 19 15,542,771 15,570,589 RGD:2325737
G Nos1 nitric oxide synthase 1 JBrowse link 12 44,214,949 44,405,530 RGD:7257607
negative regulation of ventricular cardiac muscle cell action potential term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bin1 bridging integrator 1 JBrowse link 18 25,163,575 25,222,139 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    negative regulation of biological process 5617
      negative regulation of multicellular organismal process 1381
        negative regulation of blood circulation 47
          negative regulation of gastric mucosal blood circulation 0
          negative regulation of heart contraction + 31
          negative regulation of renin secretion into blood stream 1
          negative regulation of vasoconstriction + 14
Path 2
Term Annotations click to browse term
  biological_process 19858
    multicellular organismal process 8952
      system process 3426
        circulatory system process 570
          blood circulation 542
            regulation of blood circulation 268
              negative regulation of blood circulation 47
                negative regulation of gastric mucosal blood circulation 0
                negative regulation of heart contraction + 31
                negative regulation of renin secretion into blood stream 1
                negative regulation of vasoconstriction + 14
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.