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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of response to endoplasmic reticulum stress
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Accession:GO:1903573 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of a response to endoplasmic reticulum stress.
Synonyms:exact_synonym: down regulation of ER stress response;   down regulation of cellular response to endoplasmic reticulum stress;   down regulation of response to ER stress;   down regulation of response to endoplasmic reticulum stress;   downregulation of ER stress response;   downregulation of cellular response to endoplasmic reticulum stress;   downregulation of response to ER stress;   downregulation of response to endoplasmic reticulum stress;   negative regulation of ER stress response;   negative regulation of cellular response to endoplasmic reticulum stress;   negative regulation of response to ER stress
 narrow_synonym: inhibition of ER stress response;   inhibition of cellular response to endoplasmic reticulum stress;   inhibition of response to ER stress;   inhibition of response to endoplasmic reticulum stress


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negative regulation of response to endoplasmic reticulum stress term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp11 aquaporin 11 JBrowse link 1 162,703,394 162,713,560 RGD:1600115
G Clu clusterin JBrowse link 15 42,626,612 42,665,858 RGD:1624291
RGD:1600115
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
negative regulation of ATF6-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atf6b activating transcription factor 6 beta JBrowse link 20 4,414,283 4,422,283 RGD:1624291
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
RGD:10047363
negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dnajc3 DnaJ heat shock protein family (Hsp40) member C3 JBrowse link 15 104,186,918 104,226,236 RGD:1624291
RGD:1600115
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
G Ppp1r15a protein phosphatase 1, regulatory subunit 15A JBrowse link 1 101,511,899 101,515,043 RGD:1624291
G Ppp1r15b protein phosphatase 1, regulatory subunit 15B JBrowse link 13 49,933,155 49,940,961 RGD:1624291
negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcl2l1 Bcl2-like 1 JBrowse link 3 148,259,594 148,314,191 RGD:1600115
RGD:1624291
G Creb3 cAMP responsive element binding protein 3 JBrowse link 5 59,063,532 59,068,196 RGD:1624291
G Creb3l1 cAMP responsive element binding protein 3-like 1 JBrowse link 3 80,892,433 80,933,283 RGD:1558627
RGD:1624291
G Grina glutamate ionotropic receptor NMDA type subunit associated protein 1 JBrowse link 7 117,304,742 117,307,916 RGD:1624291
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1304324
RGD:13792537
RGD:1624291
G Hspa1a heat shock protein family A (Hsp70) member 1A JBrowse link 20 4,875,834 4,881,751 RGD:1624291
G Hspa1b heat shock protein family A (Hsp70) member 1B JBrowse link 20 4,877,638 4,880,112 RGD:1624291
G Ikbkg inhibitor of nuclear factor kappa B kinase regulatory subunit gamma JBrowse link X 156,254,187 156,280,046 RGD:1624291
G Lrrk2 leucine-rich repeat kinase 2 JBrowse link 7 132,857,311 133,018,549 RGD:1624291
G Ngf nerve growth factor JBrowse link 2 204,886,158 204,939,523 RGD:10047230
G Opa1 OPA1, mitochondrial dynamin like GTPase JBrowse link 11 74,717,600 74,793,902 RGD:1624291
RGD:1600115
G Park7 Parkinsonism associated deglycase JBrowse link 5 167,982,438 168,004,724 RGD:1624291
RGD:1600115
G Pdx1 pancreatic and duodenal homeobox 1 JBrowse link 12 9,496,044 9,501,211 RGD:1624291
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
RGD:1600115
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
G Selenos selenoprotein S JBrowse link 1 126,979,579 126,989,344 RGD:1624291
RGD:1600115
G Syvn1 synoviolin 1 JBrowse link 1 221,409,281 221,416,229 RGD:1624291
G Tmbim6 transmembrane BAX inhibitor motif containing 6 JBrowse link 7 141,039,433 141,070,269 RGD:1624291
RGD:1600115
G Txndc12 thioredoxin domain containing 12 JBrowse link 5 128,450,830 128,475,858 RGD:1624291
G Wfs1 wolframin ER transmembrane glycoprotein JBrowse link 14 78,640,707 78,665,224 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
RGD:10047191
negative regulation of endoplasmic reticulum stress-induced neuron intrinsic apoptotic signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hyou1 hypoxia up-regulated 1 JBrowse link 8 48,699,796 48,711,912 RGD:1624291
RGD:1600115
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291
negative regulation of endoplasmic reticulum unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Crebrf CREB3 regulatory factor JBrowse link 10 16,693,846 16,753,162 RGD:1624291
G Xbp1 X-box binding protein 1 JBrowse link 14 85,753,736 85,758,820 RGD:1624291
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
RGD:1600115
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:10047192
RGD:1624291
G Usp14 ubiquitin specific peptidase 14 JBrowse link 18 1,178,785 1,216,573 RGD:1624291
negative regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp11 aquaporin 11 JBrowse link 1 162,703,394 162,713,560 RGD:1600115
G Ubxn1 UBX domain protein 1 JBrowse link 1 225,067,953 225,071,944 RGD:1624291
G Usp25 ubiquitin specific peptidase 25 JBrowse link 11 15,436,080 15,558,646 RGD:1624291
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bfar bifunctional apoptosis regulator JBrowse link 10
10
1,464,658
1,464,783
1,471,152
1,497,653
RGD:1624291
RGD:13792537
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 6 64,165,913 64,170,122 RGD:1600115
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1600115
G Pdia6 protein disulfide isomerase family A, member 6 JBrowse link 6 42,568,269 42,585,654 RGD:1624291
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291
negative regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:1624291
G Erlec1 endoplasmic reticulum lectin 1 JBrowse link 14 115,314,890 115,352,871 RGD:1624291
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:1624291
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:1624291
G Ubac2 UBA domain containing 2 JBrowse link 15 108,286,407 108,433,531 RGD:1624291
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 JBrowse link 20 11,700,089 11,721,823 RGD:1624291
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 JBrowse link 5 48,274,387 48,292,699 RGD:1624291
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    cellular process 17238
      negative regulation of cellular process 4952
        negative regulation of response to endoplasmic reticulum stress 48
          negative regulation of ERAD pathway + 14
          negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 5
          negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 22
          negative regulation of endoplasmic reticulum unfolded protein response + 11
Path 2
Term Annotations click to browse term
  biological_process 19334
    biological regulation 13336
      regulation of biological process 12651
        regulation of response to stimulus 3965
          regulation of response to stress 1407
            regulation of cellular response to stress 706
              regulation of response to endoplasmic reticulum stress 85
                negative regulation of response to endoplasmic reticulum stress 48
                  negative regulation of ERAD pathway + 14
                  negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation 5
                  negative regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway + 22
                  negative regulation of endoplasmic reticulum unfolded protein response + 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.