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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of production of miRNAs involved in gene silencing by miRNA
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Accession:GO:1903799 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of production of miRNAs involved in gene silencing by miRNA.
Synonyms:exact_synonym: down regulation of gene silencing by miRNA, production of miRNAs;   down regulation of miRNA processing;   down regulation of miRNA-mediated gene silencing, production of miRNAs;   down regulation of microRNA-mediated gene silencing, production of microRNAs;   down regulation of production of miRNAs involved in gene silencing by miRNA;   down regulation of production of microRNAs involved in gene silencing by microRNA;   downregulation of gene silencing by miRNA, production of miRNAs;   downregulation of miRNA processing;   downregulation of miRNA-mediated gene silencing, production of miRNAs;   downregulation of microRNA-mediated gene silencing, production of microRNAs;   downregulation of production of miRNAs involved in gene silencing by miRNA;   downregulation of production of microRNAs involved in gene silencing by microRNA;   negative regulation of gene silencing by miRNA, production of miRNAs;   negative regulation of miRNA processing;   negative regulation of miRNA-mediated gene silencing, production of miRNAs;   negative regulation of microRNA-mediated gene silencing, production of microRNAs;   negative regulation of production of microRNAs involved in gene silencing by microRNA
 narrow_synonym: inhibition of gene silencing by miRNA, production of miRNAs;   inhibition of miRNA processing;   inhibition of miRNA-mediated gene silencing, production of miRNAs;   inhibition of microRNA-mediated gene silencing, production of microRNAs;   inhibition of production of miRNAs involved in gene silencing by miRNA;   inhibition of production of microRNAs involved in gene silencing by microRNA
 related_synonym: down regulation of miRNA biogenesis;   down regulation of microRNA biogenesis;   down regulation of microRNA biosynthesis;   down regulation of microRNA biosynthetic process;   down regulation of microRNA metabolic process;   down regulation of microRNA metabolism;   downregulation of miRNA biogenesis;   downregulation of microRNA biogenesis;   downregulation of microRNA biosynthesis;   downregulation of microRNA biosynthetic process;   downregulation of microRNA metabolic process;   downregulation of microRNA metabolism;   inhibition of miRNA biogenesis;   inhibition of microRNA biogenesis;   inhibition of microRNA biosynthesis;   inhibition of microRNA biosynthetic process;   inhibition of microRNA metabolic process;   inhibition of microRNA metabolism;   negative regulation of miRNA biogenesis;   negative regulation of microRNA biogenesis;   negative regulation of microRNA biosynthesis;   negative regulation of microRNA biosynthetic process;   negative regulation of microRNA metabolic process;   negative regulation of microRNA metabolism


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negative regulation of production of miRNAs involved in gene silencing by miRNA term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Esr1 estrogen receptor 1 ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr 1:41,192,029...41,594,799
Ensembl chr 1:41,192,824...41,594,796
JBrowse link
G Ncor1 nuclear receptor co-repressor 1 ISO
IEA
(PMID:20388878)
GO_REF:0000107
RGD
Ensembl
PMID:20388878 GO_REF:0000107 NCBI chr10:48,629,121...48,772,890
Ensembl chr10:48,629,121...48,772,890
JBrowse link
G Ncor2 nuclear receptor co-repressor 2 ISO (PMID:20388878) RGD PMID:20388878 NCBI chr12:36,871,917...37,033,701
Ensembl chr12:36,871,999...37,033,701
JBrowse link
G Ppp3ca protein phosphatase 3 catalytic subunit alpha ISO (MGI:MGI:5562625|PMID:24161931) RGD PMID:24161931 MGI:MGI:5562625 NCBI chr 2:241,909,332...242,186,861
Ensembl chr 2:241,909,832...242,184,854
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO RNAcentral:URS000024463E_9606 (PMID:22269326) RGD PMID:22269326 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Tnf tumor necrosis factor ISO (PMID:31124343), (PMID:31824476) RGD PMID:31124343, PMID:31824476 NCBI chr20:5,189,382...5,192,000
Ensembl chr20:5,189,390...5,192,000
JBrowse link
G Tp53 tumor protein p53 ISO MGI:MGI:1890508 (MGI:MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:MGI:5013521 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link
G Zc3h10 zinc finger CCCH type containing 10 ISO (PMID:28431233) RGD PMID:28431233 NCBI chr 7:2,968,428...2,972,521
Ensembl chr 7:2,968,435...2,972,521
JBrowse link
G Zc3h12a zinc finger CCCH type containing 12A ISO
ISS
(PMID:22055188)
GO_REF:0000024
RGD
UniProt
PMID:22055188 GO_REF:0000024 NCBI chr 5:143,111,342...143,120,131
Ensembl chr 5:143,111,074...143,120,165
JBrowse link
G Zmpste24 zinc metallopeptidase STE24 ISO MGI:MGI:2180033|MGI:MGI:98834 (MGI:MGI:5013521|PMID:21522133) RGD PMID:21522133 MGI:MGI:5013521 NCBI chr 5:139,982,404...140,015,541
Ensembl chr 5:139,983,680...140,015,541
JBrowse link
negative regulation of pre-miRNA processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bcdin3d BCDIN3 domain containing RNA methyltransferase ISO
IBA
ISS
(PMID:23063121)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:23063121, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr 7:141,132,106...141,136,700
Ensembl chr 7:141,132,133...141,136,700
JBrowse link
G Lin28b lin-28 homolog B ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:50,482,536...50,580,273
Ensembl chr20:50,486,809...50,564,987
JBrowse link
negative regulation of primary miRNA processing term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Il6 interleukin 6 ISO UniProtKB:P40763 (PMID:31507089) RGD PMID:31507089 NCBI chr 4:3,043,231...3,047,807
Ensembl chr 4:3,043,231...3,047,807
JBrowse link
G Lin28b lin-28 homolog B ISO (PMID:18951094) RGD PMID:18951094 NCBI chr20:50,482,536...50,580,273
Ensembl chr20:50,486,809...50,564,987
JBrowse link
G Mecp2 methyl CpG binding protein 2 IMP RGD PMID:24636259 RGD:12789709 NCBI chr  X:156,650,389...156,713,813
Ensembl chr  X:156,655,960...156,705,233
JBrowse link
G Stat3 signal transducer and activator of transcription 3 ISO (PMID:31507089) RGD PMID:31507089 NCBI chr10:88,790,401...88,842,263
Ensembl chr10:88,790,408...88,842,233
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      negative regulation of metabolic process 3315
        negative regulation of macromolecule metabolic process 3042
          negative regulation of gene expression 2157
            negative regulation of production of miRNAs involved in gene silencing by miRNA 15
              negative regulation of pre-miRNA processing 2
              negative regulation of primary miRNA processing 4
Path 2
Term Annotations click to browse term
  biological_process 20014
    metabolic process 12256
      organic substance metabolic process 11636
        macromolecule metabolic process 10081
          gene expression 6295
            regulation of gene expression 4799
              negative regulation of gene expression 2157
                gene silencing 256
                  posttranscriptional gene silencing 140
                    post-transcriptional gene silencing by RNA 131
                      gene silencing by miRNA 124
                        regulation of gene silencing by miRNA 50
                          negative regulation of gene silencing by miRNA 19
                            negative regulation of production of miRNAs involved in gene silencing by miRNA 15
                              negative regulation of pre-miRNA processing 2
                              negative regulation of primary miRNA processing 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.