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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of voltage-gated potassium channel activity
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Accession:GO:1903817 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of voltage-gated potassium channel activity.
Synonyms:exact_synonym: down regulation of voltage gated potassium channel activity;   down regulation of voltage-dependent potassium channel activity;   down regulation of voltage-gated potassium ion channel activity;   down regulation of voltage-sensitive potassium channel;   downregulation of voltage gated potassium channel activity;   downregulation of voltage-dependent potassium channel activity;   downregulation of voltage-gated potassium ion channel activity;   downregulation of voltage-sensitive potassium channel;   negative regulation of voltage-dependent potassium channel activity;   negative regulation of voltage-gated potassium ion channel activity;   negative regulation of voltage-sensitive potassium channel
 narrow_synonym: inhibition of voltage gated potassium channel activity;   inhibition of voltage-dependent potassium channel activity;   inhibition of voltage-gated potassium ion channel activity;   inhibition of voltage-sensitive potassium channel


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negative regulation of voltage-gated potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 ISO (PMID:10585425) RGD PMID:10585425 NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA RGD PMID:14679187, PMID:21943416, PMID:21943417 RGD:7243967, RGD:7242916, RGD:12910700 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA RGD PMID:19219384, PMID:21943416, PMID:14679187 RGD:7243947, RGD:7242916, RGD:7243967 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA
ISO
(PMID:22987075) RGD PMID:22987075, PMID:14679187 RGD:7243967 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 ISO (PMID:9305853) RGD PMID:9305853 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
negative regulation of delayed rectifier potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ank3 ankyrin 3 ISO
ISS
(MGI:MGI:5613458|PMID:23903368)
GO_REF:0000024
RGD
UniProt
PMID:23903368 GO_REF:0000024, MGI:MGI:5613458 NCBI chr20:19,948,767...20,480,628
Ensembl chr20:20,105,047...20,480,623
JBrowse link
G Kcnab1 potassium voltage-gated channel subfamily A member regulatory beta subunit 1 IDA
IBA
IMP
PMID:21873635 RGD
GO_Central
PMID:8183366, PMID:21873635, PMID:8799886 RGD:61642, RGD:13792537, RGD:9743956 NCBI chr 2:155,555,798...156,011,438
Ensembl chr 2:155,718,359...156,009,526
JBrowse link
G Kcne1 potassium voltage-gated channel subfamily E regulatory subunit 1 IDA
IBA
ISO
PMID:19219384
PMID:21873635
(PMID:19219384)
RGD PMID:19219384, PMID:19219384, PMID:21873635 RGD:7243947, RGD:13792537 NCBI chr11:32,498,260...32,511,202
Ensembl chr11:32,498,261...32,508,420
JBrowse link
G Kcne2 potassium voltage-gated channel subfamily E regulatory subunit 2 IDA
IBA
ISO
PMID:19219384
PMID:21873635
(PMID:19219384)
RGD PMID:19219384, PMID:19219384, PMID:21873635 RGD:7243947, RGD:13792537 NCBI chr11:32,434,786...32,447,264
Ensembl chr11:32,440,237...32,447,259
JBrowse link
G Kcne3 potassium voltage-gated channel subfamily E regulatory subunit 3 IDA
IBA
ISO
PMID:12954870
PMID:21873635
(PMID:12954870)
RGD PMID:12954870, PMID:12954870, PMID:21873635 RGD:10047250, RGD:13792537 NCBI chr 1:165,189,934...165,196,949
Ensembl chr 1:165,189,985...165,196,948
JBrowse link
G Kcne4 potassium voltage-gated channel subfamily E regulatory subunit 4 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 9:84,688,873...84,693,066
Ensembl chr 9:84,689,150...84,690,338
JBrowse link
G Kcne5 potassium voltage-gated channel subfamily E regulatory subunit 5 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr  X:113,583,844...113,584,459
Ensembl chr  X:113,583,844...113,584,459
JBrowse link
G Kcnq1 potassium voltage-gated channel subfamily Q member 1 ISO (PMID:9305853) RGD PMID:9305853 NCBI chr 1:216,293,087...216,630,339
Ensembl chr 1:216,293,087...216,630,339
JBrowse link
G Kcnrg potassium channel regulator ISO
IBA
(PMID:19968958)
PMID:21873635
RGD PMID:19968958, PMID:21873635 RGD:13792537 NCBI chr15:41,937,880...41,942,205
Ensembl chr15:41,937,880...41,942,205
JBrowse link
G Mtnr1b melatonin receptor 1B IDA RGD PMID:14962062 RGD:9588668 NCBI chr 8:14,359,270...14,373,894
Ensembl chr 8:14,359,270...14,373,894
JBrowse link
G Sumo1 small ubiquitin-like modifier 1 ISO
ISS
(PMID:19223394)
GO_REF:0000024
RGD
UniProt
PMID:19223394 GO_REF:0000024 NCBI chr 9:66,453,428...66,483,614
Ensembl chr 9:66,453,438...66,483,614
JBrowse link
negative regulation of inward rectifier potassium channel activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav1 caveolin 1 IEA
ISO
GO_REF:0000107
(PMID:18923542)
Ensembl
RGD
PMID:18923542 GO_REF:0000107 NCBI chr 4:44,597,123...44,630,206
Ensembl chr 4:44,597,123...44,630,200
JBrowse link
G Snx27 sorting nexin 27 IDA RGD PMID:21422294 RGD:8554349 NCBI chr 2:195,738,613...195,821,608
Ensembl chr 2:195,738,619...195,821,608
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    negative regulation of biological process 5686
      negative regulation of transport 530
        negative regulation of transporter activity 91
          negative regulation of ion transmembrane transporter activity 82
            negative regulation of potassium ion transmembrane transporter activity 23
              negative regulation of voltage-gated potassium channel activity 13
                negative regulation of delayed rectifier potassium channel activity 11
                negative regulation of inward rectifier potassium channel activity 2
                negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization 0
                negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 0
Path 2
Term Annotations click to browse term
  biological_process 20027
    localization 6496
      establishment of localization 4911
        transport 4759
          ion transport 1787
            cation transport 1283
              monovalent inorganic cation transport 574
                potassium ion transport 257
                  regulation of potassium ion transport 116
                    regulation of potassium ion transmembrane transport 93
                      regulation of potassium ion transmembrane transporter activity 65
                        negative regulation of potassium ion transmembrane transporter activity 23
                          negative regulation of voltage-gated potassium channel activity 13
                            negative regulation of delayed rectifier potassium channel activity 11
                            negative regulation of inward rectifier potassium channel activity 2
                            negative regulation of voltage-gated potassium channel activity involved in atrial cardiac muscle cell action potential repolarization 0
                            negative regulation of voltage-gated potassium channel activity involved in ventricular cardiac muscle cell action potential repolarization 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.