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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of IRE1-mediated unfolded protein response
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Accession:GO:1903894 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of the IRE1-mediated unfolded protein response.
Synonyms:exact_synonym: regulation of IRE1 branch of UPR;   regulation of UPR signaling by IRE1 stress sensor;   regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling
 narrow_synonym: regulation of IRE1alpha unfolded protein response;   regulation of IRE1p unfolded protein response
 broad_synonym: regulation of IRE1 signal transduction pathway
 related_synonym: regulation of ERN1-mediated unfolded protein response;   regulation of IRE1 signaling in response to endoplasmic reticulum stress;   regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction


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regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cops5 COP9 signalosome subunit 5 JBrowse link 5 8,876,090 8,894,345 RGD:1624291
G Ficd FIC domain protein adenylyltransferase JBrowse link 12 48,658,283 48,663,175 RGD:1600115
RGD:1624291
negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bfar bifunctional apoptosis regulator JBrowse link 10
10
1,464,658
1,464,783
1,471,152
1,497,653
RGD:1624291
G Ddrgk1 DDRGK domain containing 1 JBrowse link 3 123,195,580 123,206,828 RGD:1624291
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 6 64,165,913 64,170,122 RGD:1600115
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1600115
G Pdia6 protein disulfide isomerase family A, member 6 JBrowse link 6 42,568,269 42,585,654 RGD:1624291
G Ufl1 Ufm1-specific ligase 1 JBrowse link 5 39,616,479 39,650,894 RGD:1624291
RGD:1600115
positive regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Agr2 anterior gradient 2, protein disulphide isomerase family member JBrowse link 6 55,465,782 55,487,087 RGD:1624291
G Tmem33 transmembrane protein 33 JBrowse link 14 42,537,352 42,559,580 RGD:1600115
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18618
      signal transduction 6968
        endoplasmic reticulum unfolded protein response 72
          IRE1-mediated unfolded protein response 15
            regulation of IRE1-mediated unfolded protein response 10
              negative regulation of IRE1-mediated unfolded protein response 6
              positive regulation of IRE1-mediated unfolded protein response 2
Path 2
Term Annotations click to browse term
  biological_process 19858
    response to stimulus 10526
      response to chemical 6305
        response to organic substance 3832
          response to topologically incorrect protein 142
            response to unfolded protein 117
              cellular response to unfolded protein 99
                endoplasmic reticulum unfolded protein response 72
                  regulation of endoplasmic reticulum unfolded protein response 25
                    regulation of IRE1-mediated unfolded protein response 10
                      negative regulation of IRE1-mediated unfolded protein response 6
                      positive regulation of IRE1-mediated unfolded protein response 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.