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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of IRE1-mediated unfolded protein response
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Accession:GO:1903895 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of the IRE1-mediated unfolded protein response.
Synonyms:exact_synonym: down regulation of IRE1 branch of UPR;   down regulation of IRE1-mediated unfolded protein response;   down regulation of UPR signaling by IRE1 stress sensor;   down regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling;   downregulation of IRE1 branch of UPR;   downregulation of IRE1-mediated unfolded protein response;   downregulation of UPR signaling by IRE1 stress sensor;   downregulation of endoplasmic reticulum unfolded protein response; IRE1 signaling;   negative regulation of IRE1 branch of UPR;   negative regulation of UPR signaling by IRE1 stress sensor;   negative regulation of endoplasmic reticulum unfolded protein response; IRE1 signaling
 narrow_synonym: down regulation of IRE1alpha unfolded protein response;   down regulation of IRE1p unfolded protein response;   downregulation of IRE1alpha unfolded protein response;   downregulation of IRE1p unfolded protein response;   inhibition of IRE1 branch of UPR;   inhibition of IRE1-mediated unfolded protein response;   inhibition of IRE1alpha unfolded protein response;   inhibition of IRE1p unfolded protein response;   inhibition of UPR signaling by IRE1 stress sensor;   inhibition of endoplasmic reticulum unfolded protein response; IRE1 signaling;   negative regulation of IRE1alpha unfolded protein response;   negative regulation of IRE1p unfolded protein response
 related_synonym: down regulation of IRE1 signaling in response to endoplasmic reticulum stress;   down regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction;   downregulation of IRE1 signaling in response to endoplasmic reticulum stress;   downregulation of inositol-requiring transmembrane kinase/endonuclease signal transduction;   inhibition of IRE1 signaling in response to endoplasmic reticulum stress;   inhibition of inositol-requiring transmembrane kinase/endonuclease signal transduction;   negative regulation of ERN1-mediated unfolded protein response;   negative regulation of IRE1 signaling in response to endoplasmic reticulum stress;   negative regulation of inositol-requiring transmembrane kinase/endonuclease signal transduction


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negative regulation of IRE1-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bfar bifunctional apoptosis regulator JBrowse link 10
10
1,464,658
1,464,783
1,471,152
1,497,653
RGD:1624291
G Ddrgk1 DDRGK domain containing 1 JBrowse link 3 123,195,580 123,206,828 RGD:1624291
G Dnajb9 DnaJ heat shock protein family (Hsp40) member B9 JBrowse link 6 64,165,913 64,170,122 RGD:1600115
G Hspa5 heat shock protein family A (Hsp70) member 5 JBrowse link 3 13,838,304 13,842,763 RGD:1600115
G Pdia6 protein disulfide isomerase family A, member 6 JBrowse link 6 42,568,269 42,585,654 RGD:1624291
G Ufl1 Ufm1-specific ligase 1 JBrowse link 5 39,616,479 39,650,894 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      signal transduction 6968
        endoplasmic reticulum unfolded protein response 72
          IRE1-mediated unfolded protein response 15
            negative regulation of IRE1-mediated unfolded protein response 6
Path 2
Term Annotations click to browse term
  biological_process 19858
    response to stimulus 10526
      cellular response to stimulus 8858
        cellular response to chemical stimulus 3497
          cellular response to organic substance 2825
            cellular response to topologically incorrect protein 122
              cellular response to unfolded protein 99
                endoplasmic reticulum unfolded protein response 72
                  regulation of endoplasmic reticulum unfolded protein response 25
                    regulation of IRE1-mediated unfolded protein response 10
                      negative regulation of IRE1-mediated unfolded protein response 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.