Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of PERK-mediated unfolded protein response
go back to main search page
Accession:GO:1903898 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of the PERK-mediated unfolded protein response.
Synonyms:exact_synonym: down regulation of PERK branch of UPR;   down regulation of PERK-mediated unfolded protein response;   down regulation of PKR-like ER kinase signal transduction;   down regulation of UPR signaling by PERK stress sensor;   down regulation of endoplasmic reticulum unfolded protein response; PERK signaling;   downregulation of PERK branch of UPR;   downregulation of PERK-mediated unfolded protein response;   downregulation of PKR-like ER kinase signal transduction;   downregulation of UPR signaling by PERK stress sensor;   downregulation of endoplasmic reticulum unfolded protein response; PERK signaling;   negative regulation of PERK branch of UPR;   negative regulation of PKR-like ER kinase signal transduction;   negative regulation of UPR signaling by PERK stress sensor;   negative regulation of endoplasmic reticulum unfolded protein response; PERK signaling
 narrow_synonym: inhibition of PERK branch of UPR;   inhibition of PERK-mediated unfolded protein response;   inhibition of PKR-like ER kinase signal transduction;   inhibition of UPR signaling by PERK stress sensor;   inhibition of endoplasmic reticulum unfolded protein response; PERK signaling
 related_synonym: down regulation of PERK signaling in response to endoplasmic reticulum stress;   downregulation of PERK signaling in response to endoplasmic reticulum stress;   inhibition of PERK signaling in response to endoplasmic reticulum stress;   negative regulation of EIF2AK3-mediated unfolded protein response;   negative regulation of PERK signaling in response to endoplasmic reticulum stress


show annotations for term's descendants       view all columns           Sort by:
 
negative regulation of PERK-mediated unfolded protein response term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nck1 NCK adaptor protein 1 JBrowse link 8 108,787,797 108,847,779 RGD:1624291
G Nck2 NCK adaptor protein 2 JBrowse link 9 50,246,767 50,373,307 RGD:1624291
G Ptpn1 protein tyrosine phosphatase, non-receptor type 1 JBrowse link 3 164,665,462 164,711,936 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19858
    cellular process 18617
      signal transduction 6968
        ER-nucleus signaling pathway 41
          PERK-mediated unfolded protein response 11
            negative regulation of PERK-mediated unfolded protein response 3
Path 2
Term Annotations click to browse term
  biological_process 19858
    response to stimulus 10526
      response to chemical 6306
        response to organic substance 3833
          response to topologically incorrect protein 142
            response to unfolded protein 117
              cellular response to unfolded protein 99
                endoplasmic reticulum unfolded protein response 72
                  regulation of endoplasmic reticulum unfolded protein response 25
                    negative regulation of endoplasmic reticulum unfolded protein response 13
                      negative regulation of PERK-mediated unfolded protein response 3
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.