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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of viral life cycle
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Accession:GO:1903901 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of viral life cycle.
Synonyms:exact_synonym: down regulation of viral life cycle;   downregulation of viral life cycle
 narrow_synonym: down regulation of viral assembly, maturation, egress, and release;   downregulation of viral assembly, maturation, egress, and release;   inhibition of viral assembly, maturation, egress, and release;   inhibition of viral life cycle;   negative regulation of viral assembly, maturation, egress, and release
 related_synonym: down regulation of lytic viral life cycle;   down regulation of viral infectious cycle;   down regulation of viral replication;   downregulation of lytic viral life cycle;   downregulation of viral infectious cycle;   downregulation of viral replication;   inhibition of lytic viral life cycle;   inhibition of viral infectious cycle;   inhibition of viral replication;   negative regulation of lytic viral life cycle;   negative regulation of viral infectious cycle;   negative regulation of viral replication


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negative regulation of viral life cycle term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Hmox1 heme oxygenase 1 ISO (PMID:25086213) RGD PMID:25086213 NCBI chr19:14,508,634...14,515,455
Ensembl chr19:14,508,616...14,515,456
JBrowse link
G Ppia peptidylprolyl isomerase A ISO (PMID:19207730), (PMID:22347431) RGD PMID:19207730, PMID:22347431 NCBI chr14:86,673,775...86,677,443
Ensembl chr14:86,673,775...86,677,443
JBrowse link
negative regulation of intracellular transport of viral material term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bst2 bone marrow stromal cell antigen 2 ISS
ISO
GO_REF:0000024
(MGI:MGI:5437405|PMID:22284121), (MGI:MGI:5437427|PMID:20686043), (MGI:MGI:5448513|PMID:21919738)
(PMID:19036818), (PMID:20686043), (PMID:20943977)
UniProt
RGD
PMID:19036818, PMID:20686043, PMID:20943977, PMID:21919738, PMID:22284121 GO_REF:0000024, MGI:MGI:5437405, MGI:MGI:5437427, MGI:MGI:5448513 NCBI chr16:19,938,781...19,942,353
Ensembl chr16:19,938,784...19,942,353
JBrowse link
G Mx2 MX dynamin like GTPase 2 ISO (PMID:20167191) RGD PMID:20167191 NCBI chr11:38,035,306...38,066,185
Ensembl chr11:38,035,450...38,059,950
JBrowse link
G Trim15 tripartite motif containing 15 ISO (PMID:18248090) RGD PMID:18248090 NCBI chr20:2,194,293...2,203,636
Ensembl chr20:2,194,709...2,201,668
JBrowse link
negative regulation of viral entry into host cell term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G AABR07015596.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr14:65,152,594...65,153,013 JBrowse link
G AABR07021463.1 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr13:73,661,131...73,661,553 JBrowse link
G Apcs amyloid P component, serum ISO
IEA
(PMID:23544079)
GO_REF:0000107
RGD
Ensembl
PMID:23544079 GO_REF:0000107 NCBI chr13:91,426,621...91,427,417
Ensembl chr13:91,426,479...91,427,575
JBrowse link
G Fcna ficolin A ISO (PMID:22851708) RGD PMID:22851708 NCBI chr 3:2,850,006...2,853,230
Ensembl chr 3:2,849,984...2,853,272
JBrowse link
G Fcnb ficolin B ISO (PMID:22851708) RGD PMID:22851708 NCBI chr 3:6,617,816...6,626,193
Ensembl chr 3:6,617,751...6,626,284
JBrowse link
G Gsn gelsolin ISO (PMID:23575248) RGD PMID:23575248 NCBI chr 3:14,456,106...14,508,922
Ensembl chr 3:14,467,330...14,508,911
JBrowse link
G Ifitm1 interferon induced transmembrane protein 1 ISO
IBA
(MGI:MGI:5437420|PMID:21253575), (MGI:MGI:5780029|PMID:25738301)
PMID:21873635
RGD PMID:21253575, PMID:25738301, PMID:21873635 MGI:MGI:5437420, MGI:MGI:5780029, RGD:13792537 NCBI chr 1:213,765,825...213,767,841
Ensembl chr 1:213,766,758...213,767,815
JBrowse link
G Ifitm2 interferon induced transmembrane protein 2 ISO
IBA
(MGI:MGI:5437420|PMID:21253575)
PMID:21873635
(PMID:21253575), (PMID:23358889)
RGD PMID:21253575, PMID:23358889, PMID:21873635 MGI:MGI:5437420, RGD:13792537 NCBI chr 1:213,750,219...213,751,399
Ensembl chr 1:213,750,192...213,751,405
JBrowse link
G Ifitm3 interferon induced transmembrane protein 3 ISO
IBA
(MGI:MGI:5437420|PMID:21253575)
PMID:21873635
(PMID:20943977), (PMID:21253575), (PMID:23358889)
RGD PMID:20943977, PMID:21253575, PMID:23358889, PMID:21873635 MGI:MGI:5437420, RGD:13792537 NCBI chr 1:213,810,712...213,811,821
Ensembl chr 1:213,810,696...213,811,901
JBrowse link
G Ifitm6 interferon induced transmembrane protein 6 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr 1:213,816,966...213,856,570
Ensembl chr 1:213,817,312...213,818,222
JBrowse link
G Ly6e lymphocyte antigen 6 family member E ISO (PMID:32641482), (PMID:32704094)
(MGI:MGI:6448667|PMID:32704094)
RGD PMID:32641482, PMID:32704094 MGI:MGI:6448667 NCBI chr 7:116,355,426...116,359,862
Ensembl chr 7:116,355,698...116,359,862
JBrowse link
G Mid2 midline 2 ISO (PMID:18248090) RGD PMID:18248090 NCBI chr  X:112,019,897...112,121,980
Ensembl chr  X:112,020,646...112,121,943
JBrowse link
G Mre11 MRE11 homolog, double strand break repair nuclease IMP RGD PMID:22850678 RGD:8693392 NCBI chr 8:13,304,355...13,350,329
Ensembl chr 8:13,305,152...13,352,489
JBrowse link
G Nbn nibrin IMP RGD PMID:22850678 RGD:8693392 NCBI chr 5:29,622,347...29,656,877
Ensembl chr 5:29,622,281...29,656,864
JBrowse link
G Ptx3 pentraxin 3 ISO (PMID:23544079) RGD PMID:23544079 NCBI chr 2:158,097,843...158,103,653
Ensembl chr 2:158,097,843...158,103,653
JBrowse link
G Rad50 RAD50 double strand break repair protein IMP RGD PMID:22850678 RGD:8693392 NCBI chr10:39,002,130...39,054,042
Ensembl chr10:39,001,498...39,054,142
JBrowse link
G RGD1561738 similar to interferon induced transmembrane protein 2 (1-8D) IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr13:73,661,005...73,661,699 JBrowse link
G RGD1565332 similar to interferon induced transmembrane protein 3 IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 NCBI chr14:65,152,594...65,153,013 JBrowse link
G Snx3 sorting nexin 3 ISO (PMID:18767904) RGD PMID:18767904 NCBI chr20:47,225,382...47,263,390
Ensembl chr20:47,225,619...47,263,390
JBrowse link
G Trim10 tripartite motif-containing 10 ISO (MGI:MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:MGI:5545996 NCBI chr20:2,182,945...2,191,640
Ensembl chr20:2,182,941...2,191,640
JBrowse link
G Trim11 tripartite motif-containing 11 ISO (PMID:18248090)
(MGI:MGI:5545996|PMID:18248090)
RGD PMID:18248090 MGI:MGI:5545996 NCBI chr10:45,322,199...45,335,030
Ensembl chr10:45,322,248...45,335,030
JBrowse link
G Trim25 tripartite motif-containing 25 ISO (MGI:MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:MGI:5545996 NCBI chr10:76,343,847...76,362,159
Ensembl chr10:76,343,847...76,362,145
JBrowse link
G Trim26 tripartite motif-containing 26 IEA
ISO
GO_REF:0000107
(PMID:18248090)
Ensembl
RGD
PMID:18248090 GO_REF:0000107 NCBI chr20:2,201,685...2,224,481
Ensembl chr20:2,201,683...2,224,463
JBrowse link
G Trim31 tripartite motif-containing 31 ISO (PMID:18248090)
(MGI:MGI:5545996|PMID:18248090)
RGD PMID:18248090 MGI:MGI:5545996 NCBI chr20:2,146,245...2,159,875
Ensembl chr20:2,146,257...2,159,631
JBrowse link
G Trim5 tripartite motif-containing 5 ISO (PMID:18248090) RGD PMID:18248090 NCBI chr 1:169,446,774...169,463,760
Ensembl chr 1:169,446,805...169,534,896
JBrowse link
G Trim59 tripartite motif-containing 59 ISO (MGI:MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:MGI:5545996 NCBI chr 2:165,629,903...165,641,751
Ensembl chr 2:165,629,918...165,641,573
JBrowse link
G Trim8 tripartite motif-containing 8 ISO (MGI:MGI:5545996|PMID:18248090) RGD PMID:18248090 MGI:MGI:5545996 NCBI chr 1:266,255,797...266,270,694
Ensembl chr 1:266,255,797...266,270,694
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    negative regulation of biological process 5686
      negative regulation of viral process 116
        negative regulation of viral life cycle 32
          negative regulation of intracellular transport of viral material 3
          negative regulation of viral budding via host ESCRT complex 0
          negative regulation of viral entry into host cell + 27
Path 2
Term Annotations click to browse term
  biological_process 20028
    interspecies interaction between organisms 1919
      symbiotic process 400
        regulation of symbiotic process 230
          regulation of viral process 213
            negative regulation of viral process 116
              negative regulation of viral life cycle 32
                negative regulation of intracellular transport of viral material 3
                negative regulation of viral budding via host ESCRT complex 0
                negative regulation of viral entry into host cell + 27
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.