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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of protein targeting to mitochondrion
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Accession:GO:1903955 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of protein targeting to mitochondrion.
Comment:An example of this is PINK1 in human (UniProt symbol Q9BXM7) in PMID:24270810 inferred from mutant phenotype.
Synonyms:exact_synonym: positive regulation of protein import into mitochondrion;   positive regulation of protein targeting to mitochondria;   positive regulation of protein-mitochondrial targeting;   up regulation of protein import into mitochondrion;   up regulation of protein targeting to mitochondria;   up regulation of protein targeting to mitochondrion;   up regulation of protein-mitochondrial targeting;   upregulation of protein import into mitochondrion;   upregulation of protein targeting to mitochondria;   upregulation of protein targeting to mitochondrion;   upregulation of protein-mitochondrial targeting
 narrow_synonym: activation of protein import into mitochondrion;   activation of protein targeting to mitochondria;   activation of protein targeting to mitochondrion;   activation of protein-mitochondrial targeting
 related_synonym: activation of mitochondrial protein import;   activation of mitochondrial translocation;   positive regulation of mitochondrial protein import;   positive regulation of mitochondrial translocation;   up regulation of mitochondrial protein import;   up regulation of mitochondrial translocation;   upregulation of mitochondrial protein import;   upregulation of mitochondrial translocation


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positive regulation of protein targeting to mitochondrion term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ablim3 actin binding LIM protein family, member 3 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr18:57,126,534...57,245,965
Ensembl chr18:57,128,399...57,245,666
JBrowse link
G Arih2 ariadne RBR E3 ubiquitin protein ligase 2 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 8:117,387,004...117,446,085
Ensembl chr 8:117,387,010...117,446,019
JBrowse link
G Atg13 autophagy related 13 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 3:80,580,549...80,614,554
Ensembl chr 3:80,581,247...80,601,410
JBrowse link
G Bap1 Brca1 associated protein 1 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr16:7,336,685...7,345,511
Ensembl chr16:7,336,685...7,345,511
JBrowse link
G Csnk2a2 casein kinase 2 alpha 2 ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr19:9,972,537...10,012,043
Ensembl chr19:9,972,537...10,012,043
JBrowse link
G Fbxw7 F-box and WD repeat domain containing 7 ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 2:184,230,191...184,309,805
Ensembl chr 2:184,231,260...184,309,664
JBrowse link
G Fzd5 frizzled class receptor 5 ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 9:71,443,784...71,445,541
Ensembl chr 9:71,443,588...71,445,739
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO (PMID:24912190) RGD PMID:24912190 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Hps4 HPS4, biogenesis of lysosomal organelles complex 3 subunit 2 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr12:50,285,239...50,315,893
Ensembl chr12:50,285,278...50,314,406
JBrowse link
G Hspa1l heat shock protein family A (Hsp70) member 1 like ISO (PMID:24270810) RGD PMID:24270810 NCBI chr20:4,879,998...4,965,191
Ensembl chr20:4,959,294...4,964,963
JBrowse link
G Htra2 HtrA serine peptidase 2 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 4:113,883,671...113,886,833
Ensembl chr 4:113,883,670...113,886,994
JBrowse link
G Huwe1 HECT, UBA and WWE domain containing E3 ubiquitin protein ligase 1 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr  X:21,474,627...21,603,348
Ensembl chr  X:21,499,934...21,598,876
JBrowse link
G Leprot leptin receptor overlapping transcript ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:120,498,910...120,511,011
Ensembl chr 5:120,498,883...120,511,017
JBrowse link
G Micall2 MICAL-like 2 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr12:16,988,013...17,016,794
Ensembl chr12:16,988,136...17,016,791
JBrowse link
G Npepps aminopeptidase puromycin sensitive ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr10:85,140,368...85,222,861
Ensembl chr10:85,140,370...85,222,861
JBrowse link
G Pink1 PTEN induced kinase 1 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:156,677,146...156,689,258
Ensembl chr 5:156,677,146...156,689,415
JBrowse link
G Prkaa1 protein kinase AMP-activated catalytic subunit alpha 1 ISO (MGI:MGI:6120139|PMID:23283301) RGD PMID:23283301 MGI:MGI:6120139 NCBI chr 2:54,857,688...54,893,404
Ensembl chr 2:54,857,688...54,893,404
JBrowse link
G Ptpn5 protein tyrosine phosphatase, non-receptor type 5 IMP RGD PMID:19625523 RGD:9835004 NCBI chr 1:103,197,918...103,258,309
Ensembl chr 1:103,197,915...103,256,823
JBrowse link
G Rac2 Rac family small GTPase 2 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 7:119,769,708...119,797,111
Ensembl chr 7:119,783,849...119,797,098
JBrowse link
G Rhou ras homolog family member U ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr19:56,431,787...56,443,896
Ensembl chr19:56,435,577...56,441,733
JBrowse link
G Rnf31 ring finger protein 31 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr15:34,270,037...34,282,385
Ensembl chr15:34,270,648...34,282,495
JBrowse link
G Sae1 SUMO1 activating enzyme subunit 1 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 1:78,277,524...78,333,281
Ensembl chr 1:78,277,515...78,333,321
JBrowse link
G Sh3glb1 SH3 domain -containing GRB2-like endophilin B1 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 2:250,709,812...250,744,216
Ensembl chr 2:250,709,439...250,744,196
JBrowse link
G Srebf2 sterol regulatory element binding transcription factor 2 ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr 7:123,381,082...123,438,605
Ensembl chr 7:123,381,077...123,438,603
JBrowse link
G Tomm7 translocase of outer mitochondrial membrane 7 ISO (PMID:24270810) RGD PMID:24270810 NCBI chr 4:7,835,949...7,842,790
Ensembl chr 4:7,835,949...7,842,789
JBrowse link
G Ube2d3 ubiquitin-conjugating enzyme E2D 3 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 2:240,626,198...240,655,874
Ensembl chr 2:240,627,436...240,655,246
JBrowse link
G Ube2j2 ubiquitin-conjugating enzyme E2, J2 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 5:173,372,659...173,387,084
Ensembl chr 5:173,372,669...173,387,104
JBrowse link
G Ube2l3 ubiquitin-conjugating enzyme E2L 3 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr11:88,047,186...88,088,477
Ensembl chr11:88,047,832...88,088,476
JBrowse link
G Ubl4b ubiquitin-like 4B ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 2:210,337,303...210,370,534 JBrowse link
G Ubl5 ubiquitin-like 5 ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 8:21,663,257...21,665,049
Ensembl chr 8:21,663,325...21,665,038
JBrowse link
G Usp36 ubiquitin specific peptidase 36 ISO (PMID:24912190) ParkinsonsUK-UCL PMID:24912190 NCBI chr10:107,292,828...107,324,355
Ensembl chr10:107,292,828...107,324,355
JBrowse link
G Vps11 VPS11 core subunit of CORVET and HOPS complexes ISO (PMID:24270810) ParkinsonsUK-UCL PMID:24270810 NCBI chr 8:48,677,492...48,692,295
Ensembl chr 8:48,677,492...48,692,295
JBrowse link
positive regulation of protein insertion into mitochondrial outer membrane term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Pdcd5 programmed cell death 5 ISO (PMID:16374546) RGD PMID:16374546 NCBI chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
Ensembl chr 1:91,173,473...91,178,801
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    positive regulation of biological process 6652
      positive regulation of establishment of protein localization 377
        positive regulation of establishment of protein localization to mitochondrion 35
          positive regulation of protein targeting to mitochondrion 33
            positive regulation of protein insertion into mitochondrial outer membrane 1
Path 2
Term Annotations click to browse term
  biological_process 20027
    localization 6496
      establishment of localization 4911
        transport 4759
          nitrogen compound transport 2155
            amide transport 1810
              peptide transport 1776
                protein transport 1717
                  intracellular protein transport 1016
                    protein targeting 325
                      protein targeting to mitochondrion 106
                        regulation of protein targeting to mitochondrion 45
                          positive regulation of protein targeting to mitochondrion 33
                            positive regulation of protein insertion into mitochondrial outer membrane 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.