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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of G protein-coupled receptor internalization
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Accession:GO:1904021 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.
Synonyms:exact_synonym: down regulation of G-protein coupled receptor internalization;   downregulation of G-protein coupled receptor internalization
 narrow_synonym: inhibition of G-protein coupled receptor internalization


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negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NECAB2 N-terminal EF-hand calcium binding protein 2 ISO (PMID:17689978) UniProtKB PMID:17689978 NCBI chr16:64,636,198...64,670,019
Ensembl chr16:83,983,626...84,013,436
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G UBQLN2 ubiquilin 2 ISO (PMID:18199683) UniProtKB PMID:18199683 NCBI chr  X:48,829,844...48,835,040
Ensembl chr  X:56,981,985...56,983,859
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12564
    metabolic process 7979
      negative regulation of metabolic process 2645
        negative regulation of macromolecule metabolic process 2388
          negative regulation of receptor internalization 15
            negative regulation of G protein-coupled receptor internalization 2
Path 2
Term Annotations click to browse term
  biological_process 12564
    biological regulation 9168
      regulation of biological process 8671
        regulation of cellular process 8197
          signal transduction 3812
            regulation of signal transduction 2547
              negative regulation of signal transduction 1153
                negative adaptation of signaling pathway 28
                  desensitization of G protein-coupled receptor signaling pathway 28
                    G protein-coupled receptor internalization 18
                      regulation of G protein-coupled receptor internalization 5
                        negative regulation of G protein-coupled receptor internalization 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.