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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of G protein-coupled receptor internalization
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Accession:GO:1904021 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.
Synonyms:exact_synonym: down regulation of G-protein coupled receptor internalization;   downregulation of G-protein coupled receptor internalization
 narrow_synonym: inhibition of G-protein coupled receptor internalization


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negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NECAB2 N-terminal EF-hand calcium binding protein 2 ISO (PMID:17689978) UniProtKB PMID:17689978 NCBI chr 5:68,313,699...68,342,253
Ensembl chr 5:68,314,000...68,378,311
JBrowse link
G UBQLN2 ubiquilin 2 ISO (PMID:18199683) UniProtKB PMID:18199683 NCBI chr  X:47,860,923...47,864,282 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    metabolic process 10658
      negative regulation of metabolic process 3108
        negative regulation of macromolecule metabolic process 2846
          negative regulation of receptor internalization 15
            negative regulation of G protein-coupled receptor internalization 2
Path 2
Term Annotations click to browse term
  biological_process 16187
    biological regulation 11555
      regulation of biological process 10957
        regulation of cellular process 10498
          signal transduction 5456
            regulation of signal transduction 2784
              negative regulation of signal transduction 1214
                negative adaptation of signaling pathway 31
                  desensitization of G protein-coupled receptor signaling pathway 31
                    G protein-coupled receptor internalization 21
                      regulation of G protein-coupled receptor internalization 5
                        negative regulation of G protein-coupled receptor internalization 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.