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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of G protein-coupled receptor internalization
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Accession:GO:1904021 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.
Synonyms:exact_synonym: down regulation of G-protein coupled receptor internalization;   downregulation of G-protein coupled receptor internalization
 narrow_synonym: inhibition of G-protein coupled receptor internalization


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negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G NECAB2 N-terminal EF-hand calcium binding protein 2 ISO (PMID:17689978) UniProtKB PMID:17689978 NCBI chr 6:4,598,752...4,641,450 JBrowse link
G UBQLN2 ubiquilin 2 IEA Ensembl GO_REF:0000107 NCBI chr  X:48,948,062...48,951,392
Ensembl chr  X:48,948,389...48,950,263
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16545
    metabolic process 10588
      negative regulation of metabolic process 3088
        negative regulation of macromolecule metabolic process 2830
          negative regulation of receptor internalization 15
            negative regulation of G protein-coupled receptor internalization 2
Path 2
Term Annotations click to browse term
  biological_process 16545
    biological regulation 12011
      regulation of biological process 11420
        regulation of cellular process 10970
          signal transduction 5925
            regulation of signal transduction 2797
              negative regulation of signal transduction 1207
                negative adaptation of signaling pathway 31
                  desensitization of G protein-coupled receptor signaling pathway 31
                    G protein-coupled receptor internalization 20
                      regulation of G protein-coupled receptor internalization 5
                        negative regulation of G protein-coupled receptor internalization 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.