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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of G protein-coupled receptor internalization
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Accession:GO:1904021 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of G protein-coupled receptor internalization.
Synonyms:exact_synonym: down regulation of G-protein coupled receptor internalization;   downregulation of G-protein coupled receptor internalization
 narrow_synonym: inhibition of G-protein coupled receptor internalization


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negative regulation of G protein-coupled receptor internalization term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Necab2 N-terminal EF-hand calcium binding protein 2 ISO (PMID:17689978) UniProtKB PMID:17689978 NCBI chrNW_004936641:3,779,024...3,802,883 JBrowse link
G Ubqln2 ubiquilin 2 ISO (PMID:18199683) UniProtKB PMID:18199683 NCBI chrNW_004936819:530,833...534,185 JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12001
    metabolic process 7670
      negative regulation of metabolic process 2538
        negative regulation of macromolecule metabolic process 2288
          negative regulation of receptor internalization 15
            negative regulation of G protein-coupled receptor internalization 2
Path 2
Term Annotations click to browse term
  biological_process 12001
    biological regulation 8793
      regulation of biological process 8336
        regulation of cellular process 7913
          signal transduction 3699
            regulation of signal transduction 2475
              negative regulation of signal transduction 1127
                negative adaptation of signaling pathway 27
                  desensitization of G protein-coupled receptor signaling pathway 27
                    G protein-coupled receptor internalization 17
                      regulation of G protein-coupled receptor internalization 5
                        negative regulation of G protein-coupled receptor internalization 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.