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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cyclin-dependent protein kinase activity
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Accession:GO:1904029 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cyclin-dependent protein kinase activity.


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negative regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 JBrowse link 5 156,876,706 156,878,486 RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1624291
G Cdkn1c cyclin-dependent kinase inhibitor 1C JBrowse link 1 216,661,067 216,663,791 RGD:1624291
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
RGD:1600115
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 JBrowse link 3 149,835,953 149,870,429 RGD:1624291
RGD:13792537
RGD:1600115
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1624291
RGD:13792537
RGD:10045364
G Cdkn1c cyclin-dependent kinase inhibitor 1C JBrowse link 1 216,661,067 216,663,791 RGD:13792537
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:1600115
G Cdkn2c cyclin-dependent kinase inhibitor 2C JBrowse link 5 129,347,731 129,352,886 RGD:1624291
G Fbxo7 F-box protein 7 JBrowse link 7 23,815,246 23,843,505 RGD:1624291
G Hexim1 HEXIM P-TEFb complex subunit 1 JBrowse link 10 91,200,874 91,202,986 RGD:1624291
RGD:13792537
RGD:1600115
G Hexim2 HEXIM P-TEFb complex subunit 2 JBrowse link 10 91,212,296 91,222,841 RGD:1624291
RGD:13792537
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 JBrowse link 10 57,309,722 57,322,140 RGD:1624291
RGD:13792537
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:1624291
G Lats1 large tumor suppressor kinase 1 JBrowse link 1 1,784,078 1,817,310 RGD:1624291
G Lats2 large tumor suppressor kinase 2 JBrowse link 15 37,943,609 37,995,175 RGD:1624291
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 JBrowse link 1 131,447,671 131,465,749 RGD:1624291
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1624291
RGD:1600115
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Tfap4 transcription factor AP-4 JBrowse link 10 11,204,616 11,222,975 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
G Wee2 WEE2 oocyte meiosis inhibiting kinase JBrowse link 4 68,604,770 68,631,341 RGD:1624291
positive regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1600115
G Hsp90ab1 heat shock protein 90 alpha family class B member 1 JBrowse link 9 17,817,791 17,823,163 RGD:13514081
RGD:1624291
G Stox1 storkhead box 1 JBrowse link 20 32,276,857 32,353,677 RGD:1624291
G Ttbk1 tau tubulin kinase 1 JBrowse link 9 16,862,305 16,899,399 RGD:1624291
positive regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AC112018.1 RGD:13792537
G AC126482.1 RGD:1600115
G Adam17 ADAM metallopeptidase domain 17 JBrowse link 6 43,400,525 43,448,280 RGD:1624291
RGD:1600115
G Akt1 AKT serine/threonine kinase 1 JBrowse link 6 137,218,398 137,239,970 RGD:1624291
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:1624291
RGD:1600115
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:1624291
G Ccnd3 cyclin D3 JBrowse link 9 15,404,816 15,410,905 RGD:1624291
RGD:1600115
G Ccnk cyclin K JBrowse link 6 132,090,235 132,113,560 RGD:1600115
G Ccnt1 cyclin T1 JBrowse link 7 140,215,052 140,245,958 RGD:1600115
G Ccnt2 cyclin T2 JBrowse link 13 44,475,959 44,516,892 RGD:1600115
G Ccny cyclin Y JBrowse link 17 62,332,537 62,462,644 RGD:1624291
RGD:13792537
G Ccnyl1 cyclin Y-like 1 JBrowse link 9 71,398,186 71,434,581 RGD:13792537
G Cdc6 cell division cycle 6 JBrowse link 10 86,819,477 86,833,301 RGD:10045360
G Cdk5r1 cyclin-dependent kinase 5 regulatory subunit 1 JBrowse link 10 67,862,054 67,863,255 RGD:1600115
G Cdk5r2 cyclin-dependent kinase 5 regulatory subunit 2 JBrowse link 9 82,120,059 82,121,527 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:10045360
G Cks1b CDC28 protein kinase regulatory subunit 1B JBrowse link 2 188,740,564 188,745,144 RGD:13792537
G Cks2 CDC28 protein kinase regulatory subunit 2 JBrowse link 17 13,587,664 13,593,423 RGD:13792537
G Egfr epidermal growth factor receptor JBrowse link 14 99,919,485 100,104,136 RGD:1624291
G Gdf9 growth differentiation factor 9 JBrowse link 10 38,782,519 38,793,238 RGD:1624291
G LOC103692976 cyclin-T1-like JBrowse link 7 140,149,991 140,172,615 RGD:1600115
G Mapre3 microtubule-associated protein, RP/EB family, member 3 JBrowse link 6 26,878,738 26,923,459 RGD:1624291
G Mnat1 MNAT1 component of CDK activating kinase JBrowse link 6 95,995,341 96,153,331 RGD:1600115
G Pdgfb platelet derived growth factor subunit B JBrowse link 7 121,215,458 121,233,092 RGD:1600115
RGD:1624291
G Pim1 Pim-1 proto-oncogene, serine/threonine kinase JBrowse link 20 8,165,423 8,169,557 RGD:1624291
G Pkd1 polycystin 1, transient receptor potential channel interacting JBrowse link 10 13,914,057 13,962,008 RGD:1624291
G Pkd2 polycystin 2, transient receptor potential cation channel JBrowse link 14 6,602,004 6,645,257 RGD:1624291
G Prox1 prospero homeobox 1 JBrowse link 13 108,382,536 108,444,107 RGD:1624291
G Psmd10 proteasome 26S subunit, non-ATPase 10 JBrowse link X 112,323,188 112,328,642 RGD:1624291
RGD:1600115
G Psrc1 proline and serine rich coiled-coil 1 JBrowse link 2 211,176,437 211,181,078 RGD:1624291
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:1624291
G Spdya speedy/RINGO cell cycle regulator family member A JBrowse link 6 23,493,686 23,543,236 RGD:1624291
RGD:13792537
RGD:1600115
G Spdye4 speedy/RINGO cell cycle regulator family member E4 JBrowse link 12 13,390,831 13,398,301 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:8553998
G Stil STIL, centriolar assembly protein JBrowse link 5 133,819,302 133,851,362 RGD:1624291
positive regulation of cyclin-dependent protein serine/threonine kinase activity involved in meiotic nuclear division term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Mastl microtubule associated serine/threonine kinase-like JBrowse link 17 89,839,562 89,875,855 RGD:1624291
regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G AABR07049223.1 RGD:1600115
G Actb actin, beta JBrowse link 12 13,715,843 13,718,813 RGD:13601989
G Bccip BRCA2 and CDKN1A interacting protein JBrowse link 1 205,777,474 205,789,887 RGD:1624291
RGD:13792537
G Blm BLM RecQ like helicase JBrowse link 1 142,246,773 142,332,616 RGD:1624291
G Ccna1 cyclin A1 JBrowse link 2 144,456,689 144,503,570 RGD:13792537
G Ccna2 cyclin A2 JBrowse link 2 123,274,727 123,282,266 RGD:13792537
G Ccnb1 cyclin B1 JBrowse link 2 30,782,133 30,791,106 RGD:13792537
G Ccnb3 cyclin B3 JBrowse link X 16,300,752 16,402,206 RGD:13792537
G Ccnc cyclin C JBrowse link 5 35,865,598 35,883,732 RGD:1600115
G Ccnd1 cyclin D1 JBrowse link 1 218,090,750 218,100,447 RGD:13792537
G Ccnd2 cyclin D2 JBrowse link 4 159,674,885 159,697,207 RGD:13792537
G Ccnd3 cyclin D3 JBrowse link 9 15,404,816 15,410,905 RGD:13792537
G Ccne1 cyclin E1 JBrowse link 1 94,485,830 94,495,112 RGD:1600115
RGD:13792537
G Ccne2 cyclin E2 JBrowse link 5 24,434,077 24,446,406 RGD:13792537
G Ccnf cyclin F JBrowse link 10 13,594,687 13,619,935 RGD:13792537
G Ccng1 cyclin G1 JBrowse link 10 25,903,925 25,910,298 RGD:13792537
G Ccng2 cyclin G2 JBrowse link 14 16,267,572 16,276,068 RGD:13792537
G Ccnh cyclin H JBrowse link 2 13,593,100 13,613,910 RGD:13792537
RGD:1624291
G Ccni cyclin I JBrowse link 14 16,341,510 16,364,326 RGD:13792537
G Ccnj cyclin J JBrowse link 1 259,926,537 259,944,275 RGD:13792537
G Ccnjl cyclin J-like JBrowse link 10 29,122,713 29,181,610 RGD:13792537
G Ccnl1 cyclin L1 JBrowse link 2 157,747,295 157,759,838 RGD:1600115
G Ccnl2 cyclin L2 JBrowse link 5 173,256,301 173,268,279 RGD:1600115
G Ccno cyclin O JBrowse link 2 44,857,043 44,860,317 RGD:13792537
G Ccnq cyclin Q JBrowse link 10 66,019,519 66,020,682 RGD:1600115
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 JBrowse link 3 149,835,953 149,870,429 RGD:632478
G Cdk5rap3 CDK5 regulatory subunit associated protein 3 JBrowse link 10 84,780,644 84,789,800 RGD:632478
RGD:13792537
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:1624291
G Cdkn2c cyclin-dependent kinase inhibitor 2C JBrowse link 5 129,347,731 129,352,886 RGD:1624291
G Cnppd1 cyclin Pas1/PHO80 domain containing 1 JBrowse link 9 82,338,865 82,345,262 RGD:1600115
G Gtpbp4 GTP binding protein 4 JBrowse link 17 63,111,086 63,145,618 RGD:1624291
RGD:1600115
G LOC100909712 cyclin-L1-like JBrowse link 2 157,759,898 157,763,422 RGD:1600115
G Mnat1 MNAT1 component of CDK activating kinase JBrowse link 6 95,995,341 96,153,331 RGD:13792537
G NEWGENE_1306399 cyclin J JBrowse link 1 260,092,938 260,110,729 RGD:13792537
G Rgcc regulator of cell cycle JBrowse link 15 61,551,861 61,564,695 RGD:633887
G Sfn stratifin JBrowse link 5 151,823,422 151,824,937 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19334
    regulation of biological process 12651
      regulation of cellular process 11990
        regulation of cell cycle 1066
          regulation of cyclin-dependent protein kinase activity 92
            negative regulation of cyclin-dependent protein kinase activity + 26
            positive regulation of cyclin-dependent protein kinase activity + 41
            regulation of cyclin-dependent protein serine/threonine kinase activity + 88
Path 2
Term Annotations click to browse term
  biological_process 19334
    metabolic process 11555
      organic substance metabolic process 10949
        macromolecule metabolic process 9418
          protein metabolic process 5973
            protein modification process 3851
              cellular protein modification process 3851
                protein phosphorylation 1957
                  regulation of protein phosphorylation 1508
                    regulation of protein kinase activity 758
                      regulation of cyclin-dependent protein kinase activity 92
                        negative regulation of cyclin-dependent protein kinase activity + 26
                        positive regulation of cyclin-dependent protein kinase activity + 41
                        regulation of cyclin-dependent protein serine/threonine kinase activity + 88
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.