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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cyclin-dependent protein kinase activity
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Accession:GO:1904030 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity.
Synonyms:exact_synonym: down regulation of cyclin-dependent protein kinase activity;   downregulation of cyclin-dependent protein kinase activity
 narrow_synonym: inhibition of cyclin-dependent protein kinase activity


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negative regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G CAMK2N1 calcium/calmodulin dependent protein kinase II inhibitor 1 JBrowse link 1 20,482,391 20,486,210 RGD:2290271
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 36,676,463 36,687,332 RGD:2290271
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 12,717,270 12,722,383 RGD:2290271
G CDKN1C cyclin dependent kinase inhibitor 1C JBrowse link 11 2,883,218 2,885,775 RGD:2290271
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G APC APC regulator of WNT signaling pathway JBrowse link 5 112,707,498 112,846,239 RGD:2290271
G CASP3 caspase 3 JBrowse link 4 184,627,696 184,649,475 RGD:2290271
G CDK5RAP1 CDK5 regulatory subunit associated protein 1 JBrowse link 20 33,358,839 33,403,030 RGD:2290271
G CDKN1A cyclin dependent kinase inhibitor 1A JBrowse link 6 36,676,463 36,687,332 RGD:2290271
G CDKN1B cyclin dependent kinase inhibitor 1B JBrowse link 12 12,717,270 12,722,383 RGD:2290271
G CDKN1C cyclin dependent kinase inhibitor 1C JBrowse link 11 2,883,218 2,885,775 RGD:2290271
G CDKN2A cyclin dependent kinase inhibitor 2A JBrowse link 9 21,967,752 21,995,324 RGD:2290271
G CDKN2B cyclin dependent kinase inhibitor 2B JBrowse link 9 22,002,903 22,009,313 RGD:2290271
G CDKN2C cyclin dependent kinase inhibitor 2C JBrowse link 1 50,968,695 50,974,634 RGD:2290271
G CDKN2D cyclin dependent kinase inhibitor 2D JBrowse link 19 10,566,460 10,568,979 RGD:2290271
G CEBPA CCAAT enhancer binding protein alpha JBrowse link 19 33,299,934 33,302,564 RGD:2290271
G FBXO7 F-box protein 7 JBrowse link 22 32,474,682 32,498,831 RGD:2290271
G HEXIM1 HEXIM P-TEFb complex subunit 1 JBrowse link 17 45,148,475 45,152,099 RGD:2290271
G HEXIM2 HEXIM P-TEFb complex subunit 2 JBrowse link 17 45,159,948 45,170,040 RGD:2290271
G HHEX hematopoietically expressed homeobox JBrowse link 10 92,689,955 92,695,647 RGD:2290271
G INCA1 inhibitor of CDK, cyclin A1 interacting protein 1 JBrowse link 17 4,988,130 5,006,093 RGD:2290271
G IPO5 importin 5 JBrowse link 13 97,953,641 98,024,296 RGD:2290271
G IPO7 importin 7 JBrowse link 11 9,384,652 9,448,127 RGD:2290271
G KAT2B lysine acetyltransferase 2B JBrowse link 3 20,040,407 20,154,404 RGD:2290271
G LATS1 large tumor suppressor kinase 1 JBrowse link 6 149,658,153 149,718,256 RGD:2290271
G LATS2 large tumor suppressor kinase 2 JBrowse link 13 20,973,036 21,061,586 RGD:2290271
G MEN1 menin 1 JBrowse link 11 64,803,514 64,811,294 RGD:2290271
G MYOCD myocardin JBrowse link 17 12,665,890 12,768,949 RGD:2290271
G NR2F2 nuclear receptor subfamily 2 group F member 2 JBrowse link 15 96,326,046 96,340,263 RGD:2290271
G PLK1 polo like kinase 1 JBrowse link 16 23,678,889 23,690,367 RGD:2290271
G PTEN phosphatase and tensin homolog JBrowse link 10 87,863,625 87,971,930 RGD:2290271
G TFAP4 transcription factor AP-4 JBrowse link 16 4,257,186 4,273,023 RGD:2290271
G TNFAIP3 TNF alpha induced protein 3 JBrowse link 6 137,866,317 137,883,312 RGD:2290271
G WEE2 WEE2 oocyte meiosis inhibiting kinase JBrowse link 7 141,708,353 141,731,271 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17988
    cellular process 16264
      cell cycle 1915
        regulation of cell cycle 1256
          regulation of cyclin-dependent protein kinase activity 103
            negative regulation of cyclin-dependent protein kinase activity 30
              negative regulation of cyclin-dependent protein serine/threonine kinase activity + 29
Path 2
Term Annotations click to browse term
  biological_process 17988
    biological regulation 12616
      regulation of biological process 11926
        regulation of metabolic process 6858
          regulation of cellular metabolic process 6379
            regulation of phosphorus metabolic process 1836
              regulation of phosphate metabolic process 1835
                regulation of phosphorylation 1637
                  regulation of kinase activity 914
                    regulation of protein kinase activity 805
                      negative regulation of protein kinase activity 231
                        negative regulation of cyclin-dependent protein kinase activity 30
                          negative regulation of cyclin-dependent protein serine/threonine kinase activity + 29
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.