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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cyclin-dependent protein kinase activity
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Accession:GO:1904030 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cyclin-dependent protein kinase activity.
Synonyms:exact_synonym: down regulation of cyclin-dependent protein kinase activity;   downregulation of cyclin-dependent protein kinase activity
 narrow_synonym: inhibition of cyclin-dependent protein kinase activity


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negative regulation of cyclin-dependent protein kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Camk2n1 calcium/calmodulin-dependent protein kinase II inhibitor 1 JBrowse link 5 156,876,706 156,878,486 RGD:1624291
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1624291
G Cdkn1c cyclin-dependent kinase inhibitor 1C JBrowse link 1 216,661,067 216,663,791 RGD:1624291
negative regulation of cyclin-dependent protein serine/threonine kinase activity term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Apc APC regulator of WNT signaling pathway JBrowse link 18 27,011,710 27,106,323 RGD:1624291
RGD:1600115
G Casp3 caspase 3 JBrowse link 16 48,845,011 48,863,249 RGD:1624291
G Cdk5rap1 CDK5 regulatory subunit associated protein 1 JBrowse link 3 149,835,953 149,870,429 RGD:1624291
RGD:13792537
RGD:1600115
G Cdkn1a cyclin-dependent kinase inhibitor 1A JBrowse link 20 6,348,422 6,358,864 RGD:1624291
G Cdkn1b cyclin-dependent kinase inhibitor 1B JBrowse link 4 168,689,043 168,694,159 RGD:1624291
RGD:13792537
RGD:10045364
G Cdkn1c cyclin-dependent kinase inhibitor 1C JBrowse link 1 216,661,067 216,663,791 RGD:13792537
G Cdkn2a cyclin-dependent kinase inhibitor 2A JBrowse link 5 107,823,323 107,832,405 RGD:1624291
G Cdkn2b cyclin-dependent kinase inhibitor 2B JBrowse link 5 107,834,353 107,857,428 RGD:1600115
G Cdkn2c cyclin-dependent kinase inhibitor 2C JBrowse link 5 129,347,731 129,352,886 RGD:1624291
G Fbxo7 F-box protein 7 JBrowse link 7 23,815,246 23,843,505 RGD:1624291
G Hexim1 HEXIM P-TEFb complex subunit 1 JBrowse link 10 91,200,874 91,202,986 RGD:1624291
RGD:13792537
RGD:1600115
G Hexim2 HEXIM P-TEFb complex subunit 2 JBrowse link 10 91,212,296 91,222,841 RGD:1624291
RGD:13792537
G Hhex hematopoietically expressed homeobox JBrowse link 1 256,101,994 256,107,581 RGD:1624291
G Inca1 inhibitor of CDK, cyclin A1 interacting protein 1 JBrowse link 10 57,309,722 57,322,140 RGD:1624291
RGD:13792537
G Kat2b lysine acetyltransferase 2B JBrowse link 9 4,440,982 4,492,949 RGD:1624291
G Lats1 large tumor suppressor kinase 1 JBrowse link 1 1,784,078 1,817,310 RGD:1624291
G Lats2 large tumor suppressor kinase 2 JBrowse link 15 37,943,609 37,995,175 RGD:1624291
G Men1 menin 1 JBrowse link 1 221,704,394 221,710,343 RGD:1624291
G Myocd myocardin JBrowse link 10 51,682,053 51,781,458 RGD:1624291
RGD:1600115
G Nr2f2 nuclear receptor subfamily 2, group F, member 2 JBrowse link 1 131,447,671 131,465,749 RGD:1624291
G Plk1 polo-like kinase 1 JBrowse link 1 192,115,990 192,125,969 RGD:1624291
RGD:1600115
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
G Tfap4 transcription factor AP-4 JBrowse link 10 11,204,616 11,222,975 RGD:1624291
G Tnfaip3 TNF alpha induced protein 3 JBrowse link 1 14,401,103 14,416,369 RGD:1624291
G Wee2 WEE2 oocyte meiosis inhibiting kinase JBrowse link 4 68,604,770 68,631,341 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19332
    cellular process 17237
      cell cycle 1620
        regulation of cell cycle 1066
          regulation of cyclin-dependent protein kinase activity 92
            negative regulation of cyclin-dependent protein kinase activity 26
              negative regulation of cyclin-dependent protein serine/threonine kinase activity + 25
Path 2
Term Annotations click to browse term
  biological_process 19332
    biological regulation 13335
      regulation of biological process 12650
        regulation of metabolic process 6536
          regulation of cellular metabolic process 6024
            regulation of phosphorus metabolic process 1854
              regulation of phosphate metabolic process 1853
                regulation of phosphorylation 1656
                  regulation of kinase activity 868
                    regulation of protein kinase activity 758
                      negative regulation of protein kinase activity 223
                        negative regulation of cyclin-dependent protein kinase activity 26
                          negative regulation of cyclin-dependent protein serine/threonine kinase activity + 25
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.