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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of spontaneous neurotransmitter secretion
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Accession:GO:1904049 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of spontaneous neurotransmitter secretion.
Comment:An example of this is PARK2 / parkin in human (O60260) in PMID:22314364 (inferred from mutant phenotype).
Synonyms:exact_synonym: down regulation of spontaneous neurotransmitter secretion;   down regulation of stimulus-independent neurotransmitter secretion;   downregulation of spontaneous neurotransmitter secretion;   downregulation of stimulus-independent neurotransmitter secretion;   negative regulation of stimulus-independent neurotransmitter secretion
 narrow_synonym: inhibition of spontaneous neurotransmitter secretion;   inhibition of stimulus-independent neurotransmitter secretion


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negative regulation of spontaneous neurotransmitter secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ppp1r9a protein phosphatase 1, regulatory subunit 9A JBrowse link 4 29,976,485 30,247,371 RGD:10002752
G Prkn parkin RBR E3 ubiquitin protein ligase JBrowse link 1 48,880,015 50,069,998 RGD:1624291

Term paths to the root
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Term Annotations click to browse term
  biological_process 19317
    signaling 7394
      negative regulation of signaling 1354
        negative regulation of synaptic transmission 88
          negative regulation of neurotransmitter secretion 12
            negative regulation of spontaneous neurotransmitter secretion 2
Path 2
Term Annotations click to browse term
  biological_process 19317
    cellular process 17226
      cell communication 7486
        cell-cell signaling 1652
          synaptic signaling 895
            trans-synaptic signaling 871
              anterograde trans-synaptic signaling 862
                chemical synaptic transmission 862
                  neurotransmitter secretion 207
                    regulation of neurotransmitter secretion 150
                      negative regulation of neurotransmitter secretion 12
                        negative regulation of spontaneous neurotransmitter secretion 2
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.