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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of TORC1 signaling
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Accession:GO:1904262 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
Synonyms:exact_synonym: down regulation of TORC1 signal transduction;   down regulation of TORC1 signaling;   downregulation of TORC1 signal transduction;   downregulation of TORC1 signaling;   negative regulation of TORC1 signal transduction
 narrow_synonym: inhibition of TORC1 signal transduction;   inhibition of TORC1 signaling


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negative regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ALG13 ALG13 UDP-N-acetylglucosaminyltransferase subunit ISO (MGI:MGI:6306805|PMID:30872163) MGI PMID:30872163 MGI:MGI:6306805 NCBI chr  X:84,752,284...84,825,414 JBrowse link
G ATM ATM serine/threonine kinase IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 5:24,180,129...24,297,207
Ensembl chr 5:24,182,135...24,297,207
JBrowse link
G BMT2 base methyltransferase of 25S rRNA 2 homolog IEA Ensembl GO_REF:0000107 NCBI chr14:52,363,629...52,456,440
Ensembl chr14:52,366,219...52,456,404
JBrowse link
G C10H12orf66 chromosome 10 C12orf66 homolog IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:6,977,602...6,998,204
Ensembl chr10:6,979,624...6,998,138
JBrowse link
G CASTOR1 cytosolic arginine sensor for mTORC1 subunit 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr26:23,439,472...23,443,950
Ensembl chr26:23,439,475...23,443,955
JBrowse link
G CASTOR2 cytosolic arginine sensor for mTORC1 subunit 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:5,565,723...5,602,799
Ensembl chr 6:5,548,758...5,598,582
JBrowse link
G DEPDC5 DEP domain containing 5, GATOR1 subcomplex subunit ISO (PMID:25457612), (PMID:29769719) UniProtKB PMID:25457612, PMID:29769719 NCBI chr26:24,629,369...24,754,728
Ensembl chr26:24,630,295...24,754,256
JBrowse link
G FNIP1 folliculin interacting protein 1 ISO (MGI:MGI:5635927|PMID:25775561) MGI PMID:25775561 MGI:MGI:5635927 NCBI chr11:19,979,294...20,134,341
Ensembl chr11:19,979,163...20,134,229
JBrowse link
G FNIP2 folliculin interacting protein 2 ISO (MGI:MGI:5635927|PMID:25775561) MGI PMID:25775561 MGI:MGI:5635927 NCBI chr15:55,871,782...55,962,676
Ensembl chr15:55,830,806...55,959,052
JBrowse link
G ITFG2 integrin alpha FG-GAP repeat containing 2 IEA Ensembl GO_REF:0000107 NCBI chr27:41,933,741...41,944,464
Ensembl chr27:41,934,575...41,944,472
JBrowse link
G KPTN kaptin, actin binding protein IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:108,535,140...108,544,405
Ensembl chr 1:108,535,681...108,543,164
JBrowse link
G LOC106559493 small regulatory polypeptide of amino acid response-like ISO (MGI:MGI:5822922|PMID:28024296)
(PMID:28024296)
UniProtKB PMID:28024296 MGI:MGI:5822922 NCBI chr11:52,424,607...52,427,288
Ensembl chr11:52,426,076...52,426,303
JBrowse link
G RNF152 ring finger protein 152 IEA Ensembl GO_REF:0000107 NCBI chr 1:14,914,508...15,001,843
Ensembl chr 1:14,985,769...14,986,380
JBrowse link
G SESN1 sestrin 1 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr12:65,958,995...66,057,369
Ensembl chr12:65,960,066...66,057,035
JBrowse link
G SESN2 sestrin 2 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr 2:72,151,464...72,168,861
Ensembl chr 2:72,151,868...72,168,492
JBrowse link
G SESN3 sestrin 3 IBA
IEA
(PMID:21873635) GO_Central
Ensembl
PMID:21873635 GO_REF:0000107 NCBI chr21:5,827,957...5,899,540
Ensembl chr21:5,777,780...5,892,805
JBrowse link
G STK11 serine/threonine kinase 11 IEA Ensembl GO_REF:0000107 NCBI chr20:57,558,966...57,579,163
Ensembl chr20:57,559,424...57,579,118
JBrowse link
G SZT2 SZT2 subunit of KICSTOR complex IEA Ensembl GO_REF:0000107 NCBI chr15:16,729,068...16,780,549
Ensembl chr15:16,728,758...16,780,325
JBrowse link
G TSC2 TSC complex subunit 2 ISO (MGI:MGI:5509101|PMID:23878245) ParkinsonsUK-UCL PMID:23878245 MGI:MGI:5509101 NCBI chr 6:38,865,509...38,898,977
Ensembl chr 6:38,865,507...38,898,960
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16187
    cellular process 15465
      signal transduction 5456
        intracellular signal transduction 2465
          TOR signaling 123
            negative regulation of TOR signaling 45
              negative regulation of TORC1 signaling 19
Path 2
Term Annotations click to browse term
  biological_process 16187
    biological regulation 11555
      regulation of biological process 10957
        regulation of cellular process 10498
          signal transduction 5456
            intracellular signal transduction 2465
              TOR signaling 123
                regulation of TOR signaling 102
                  negative regulation of TOR signaling 45
                    negative regulation of TORC1 signaling 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.