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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of TORC1 signaling
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Accession:GO:1904262 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of TORC1 signaling.
Synonyms:exact_synonym: down regulation of TORC1 signal transduction;   down regulation of TORC1 signaling;   downregulation of TORC1 signal transduction;   downregulation of TORC1 signaling;   negative regulation of TORC1 signal transduction
 narrow_synonym: inhibition of TORC1 signal transduction;   inhibition of TORC1 signaling


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negative regulation of TORC1 signaling term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Alg13 ALG13, UDP-N-acetylglucosaminyltransferase subunit ISO MGI:MGI:6358168 (MGI:MGI:6306805|PMID:30872163) RGD PMID:30872163 MGI:MGI:6306805 NCBI chr  X:115,561,329...115,589,792
Ensembl chr  X:115,561,332...115,619,505
JBrowse link
G Atm ATM serine/threonine kinase ISO
IBA
(PMID:23878245)
(MGI:MGI:5509101|PMID:23878245)
PMID:21873635
RGD PMID:23878245, PMID:21873635 MGI:MGI:5509101, RGD:13792537 NCBI chr 8:58,015,938...58,119,973
Ensembl chr 8:58,015,940...58,120,045
JBrowse link
G Bmt2 base methyltransferase of 25S rRNA 2 homolog ISO (PMID:29123071) RGD PMID:29123071 NCBI chr 4:40,064,131...40,136,074
Ensembl chr 4:40,063,932...40,136,061
JBrowse link
G Castor1 cytosolic arginine sensor for mTORC1 subunit 1 ISO
IBA
ISS
(PMID:26972053)
PMID:21873635
GO_REF:0000024
RGD
UniProt
PMID:26972053, PMID:21873635 GO_REF:0000024, RGD:13792537 NCBI chr14:84,447,552...84,457,396
Ensembl chr14:84,447,885...84,452,367
JBrowse link
G Castor2 cytosolic arginine sensor for mTORC1 subunit 2 ISO
IBA
(PMID:26972053)
PMID:21873635
RGD PMID:26972053, PMID:21873635 RGD:13792537 NCBI chr12:25,595,800...25,638,806
Ensembl chr12:25,601,404...25,638,797
JBrowse link
G Depdc5 DEP domain containing 5, GATOR1 subcomplex subunit ISO (PMID:25457612), (PMID:29769719) RGD PMID:25457612, PMID:29769719 NCBI chr14:83,089,000...83,219,576
Ensembl chr14:83,089,000...83,219,464
JBrowse link
G Fnip1 folliculin interacting protein 1 ISO MGI:MGI:2442184|MGI:MGI:2683054 (MGI:MGI:5635927|PMID:25775561) RGD PMID:25775561 MGI:MGI:5635927 NCBI chr10:39,786,687...39,870,188 JBrowse link
G Fnip2 folliculin interacting protein 2 ISO MGI:MGI:2442184|MGI:MGI:2444668 (MGI:MGI:5635927|PMID:25775561) RGD PMID:25775561 MGI:MGI:5635927 NCBI chr 2:178,223,561...178,334,925
Ensembl chr 2:178,225,915...178,334,900
JBrowse link
G Itfg2 integrin alpha FG-GAP repeat containing 2 ISO (PMID:28199306) RGD PMID:28199306 NCBI chr 4:161,730,643...161,744,281
Ensembl chr 4:161,730,641...161,743,896
JBrowse link
G Kptn kaptin (actin binding protein) ISO (PMID:28199306) RGD PMID:28199306 NCBI chr 1:78,015,714...78,016,508 JBrowse link
G Kptn kaptin IBA PMID:21873635 GO_Central PMID:21873635 RGD:13792537 Ensembl chr 1:78,015,722...78,023,676 JBrowse link
G RGD1565498 similar to Hypothetical protein LOC270802 ISO
IBA
(PMID:28199306)
PMID:21873635
RGD PMID:28199306, PMID:21873635 RGD:13792537 NCBI chr 7:63,922,871...63,937,721
Ensembl chr 7:63,922,879...63,936,385
JBrowse link
G Rnf152 ring finger protein 152 ISO
ISS
(PMID:25936802)
GO_REF:0000024
(MGI:MGI:5644195|PMID:25936802)
RGD
UniProt
PMID:25936802 GO_REF:0000024, MGI:MGI:5644195 NCBI chr13:25,183,295...25,262,785
Ensembl chr13:25,186,106...25,262,469
JBrowse link
G Sesn1 sestrin 1 ISO
IBA
(MGI:MGI:5604284|PMID:25259925)
PMID:21873635
(PMID:18692468), (PMID:25263562)
RGD PMID:18692468, PMID:25259925, PMID:25263562, PMID:21873635 MGI:MGI:5604284, RGD:13792537 NCBI chr20:46,667,116...46,758,306
Ensembl chr20:46,667,121...46,758,305
JBrowse link
G Sesn2 sestrin 2 ISO
IBA
(PMID:18692468), (PMID:24947615), (PMID:25263562), (PMID:25457612), (PMID:26449471), (PMID:26586190), (PMID:26612684)
PMID:21873635
(MGI:MGI:5604284|PMID:25259925), (MGI:MGI:5688277|PMID:24947615)
RGD PMID:18692468, PMID:24947615, PMID:25259925, PMID:25263562, PMID:25457612, PMID:26449471, PMID:26586190, PMID:26612684, PMID:21873635 MGI:MGI:5604284, MGI:MGI:5688277, RGD:13792537 NCBI chr 5:150,684,891...150,703,846
Ensembl chr 5:150,684,133...150,704,117
JBrowse link
G Sesn3 sestrin 3 ISO
IBA
(PMID:25263562)
PMID:21873635
(MGI:MGI:5604284|PMID:25259925)
RGD PMID:25259925, PMID:25263562, PMID:21873635 MGI:MGI:5604284, RGD:13792537 NCBI chr 8:12,823,060...12,878,749
Ensembl chr 8:12,823,155...12,872,705
JBrowse link
G Stk11 serine/threonine kinase 11 ISO
IEA
(PMID:23878245)
GO_REF:0000107
RGD
Ensembl
PMID:23878245 GO_REF:0000107 NCBI chr 7:12,440,751...12,457,513
Ensembl chr 7:12,440,751...12,457,513
JBrowse link
G Szt2 SZT2 subunit of KICSTOR complex ISO (PMID:28199306), (PMID:28199315)
(MGI:MGI:5883356|PMID:28199306), (MGI:MGI:5897504|PMID:28199315)
RGD PMID:28199306, PMID:28199315 MGI:MGI:5883356, MGI:MGI:5897504 NCBI chr 5:137,192,120...137,238,384
Ensembl chr 5:137,190,875...137,238,354
JBrowse link
G Tsc2 TSC complex subunit 2 ISO (MGI:MGI:5509101|PMID:23878245) RGD PMID:23878245 MGI:MGI:5509101 NCBI chr10:13,962,006...13,996,684
Ensembl chr10:13,961,947...13,996,584
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    cellular process 18791
      signal transduction 7015
        intracellular signal transduction 2615
          TOR signaling 132
            negative regulation of TOR signaling 49
              negative regulation of TORC1 signaling 19
Path 2
Term Annotations click to browse term
  biological_process 20017
    biological regulation 13767
      regulation of biological process 13081
        regulation of cellular process 12570
          signal transduction 7015
            intracellular signal transduction 2615
              TOR signaling 132
                regulation of TOR signaling 109
                  negative regulation of TOR signaling 49
                    negative regulation of TORC1 signaling 19
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.