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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of ERAD pathway
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Accession:GO:1904292 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of ERAD pathway.
Synonyms:exact_synonym: regulation of endoplasmic reticulum-associated degradation
 related_synonym: regulation of ER-associated degradation pathway;   regulation of endoplasmic reticulum-associated protein degradation pathway


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regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Usp19 ubiquitin specific peptidase 19 JBrowse link 8 117,280,690 117,291,729 RGD:1624291
RGD:1600115
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
RGD:1600115
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:10047192
RGD:1624291
G Usp14 ubiquitin specific peptidase 14 JBrowse link 18 1,178,785 1,216,573 RGD:1624291
negative regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp11 aquaporin 11 JBrowse link 1 162,703,394 162,713,560 RGD:1600115
RGD:1624291
G Ubxn1 UBX domain protein 1 JBrowse link 1 225,067,953 225,071,944 RGD:1624291
G Usp25 ubiquitin specific peptidase 25 JBrowse link 11 15,436,080 15,558,646 RGD:1624291
negative regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:1624291
G Erlec1 endoplasmic reticulum lectin 1 JBrowse link 14 115,314,890 115,352,871 RGD:1624291
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:1624291
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:1624291
G Ubac2 UBA domain containing 2 JBrowse link 15 108,286,407 108,433,531 RGD:1624291
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 JBrowse link 20 11,700,089 11,721,823 RGD:1624291
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 JBrowse link 5 48,274,387 48,292,699 RGD:1624291
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:1624291
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1600115
RGD:1624291
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:10047316
RGD:1624291
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:1600115
RGD:1624291
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
positive regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atxn3 ataxin 3 JBrowse link 6 125,817,420 125,853,461 RGD:1624291
G Bag6 BAG cochaperone 6 JBrowse link 20 5,124,512 5,138,084 RGD:1624291
G Rnf185 ring finger protein 185 JBrowse link 14 83,648,400 83,685,273 RGD:1600115
RGD:1624291
G Rnft1 ring finger protein, transmembrane 1 JBrowse link 10 73,807,455 73,821,178 RGD:1624291
G Tmem259 transmembrane protein 259 JBrowse link 7 12,771,239 12,777,901 RGD:1624291
RGD:13792537
G Tmem67 transmembrane protein 67 JBrowse link 5 25,666,138 25,721,056 RGD:8554391
G Usp13 ubiquitin specific peptidase 13 JBrowse link 2 119,197,153 119,317,507 RGD:1624291
positive regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1624291
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 3 151,232,741 151,258,559 RGD:1624291
regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:1624291
RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    cellular process 18362
      regulation of cellular process 12334
        regulation of cellular response to stress 714
          regulation of response to endoplasmic reticulum stress 87
            regulation of ERAD pathway 29
              negative regulation of ERAD pathway + 14
              positive regulation of ERAD pathway + 15
              regulation of ER-associated ubiquitin-dependent protein catabolic process + 8
              regulation of retrograde protein transport, ER to cytosol + 12
Path 2
Term Annotations click to browse term
  biological_process 19578
    biological regulation 13539
      regulation of biological process 12843
        regulation of metabolic process 6834
          regulation of primary metabolic process 5871
            regulation of protein metabolic process 2951
              regulation of cellular protein metabolic process 2762
                regulation of cellular protein catabolic process 261
                  regulation of proteolysis involved in cellular protein catabolic process 226
                    regulation of proteasomal protein catabolic process 192
                      regulation of ERAD pathway 29
                        negative regulation of ERAD pathway + 14
                        positive regulation of ERAD pathway + 15
                        regulation of ER-associated ubiquitin-dependent protein catabolic process + 8
                        regulation of retrograde protein transport, ER to cytosol + 12
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.