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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of ERAD pathway
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Accession:GO:1904293 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of ERAD pathway.
Synonyms:exact_synonym: down regulation of ERAD pathway;   down regulation of endoplasmic reticulum-associated degradation;   downregulation of ERAD pathway;   downregulation of endoplasmic reticulum-associated degradation;   negative regulation of endoplasmic reticulum-associated degradation
 narrow_synonym: inhibition of ERAD pathway;   inhibition of endoplasmic reticulum-associated degradation
 related_synonym: down regulation of ER-associated degradation pathway;   down regulation of endoplasmic reticulum-associated protein degradation pathway;   downregulation of ER-associated degradation pathway;   downregulation of endoplasmic reticulum-associated protein degradation pathway;   inhibition of ER-associated degradation pathway;   inhibition of endoplasmic reticulum-associated protein degradation pathway;   negative regulation of ER-associated degradation pathway;   negative regulation of endoplasmic reticulum-associated protein degradation pathway


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negative regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Aqp11 aquaporin 11 JBrowse link 1 162,703,394 162,713,560 RGD:1600115
RGD:1624291
G Ubxn1 UBX domain protein 1 JBrowse link 1 225,067,953 225,071,944 RGD:1624291
G Usp25 ubiquitin specific peptidase 25 JBrowse link 11 15,436,080 15,558,646 RGD:1624291
negative regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
RGD:1600115
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:10047192
RGD:1624291
G Usp14 ubiquitin specific peptidase 14 JBrowse link 18 1,178,785 1,216,573 RGD:1624291
negative regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Derl2 derlin 2 JBrowse link 10 57,641,682 57,653,554 RGD:1624291
G Derl3 derlin 3 JBrowse link 20 13,692,102 13,707,645 RGD:1624291
G Erlec1 endoplasmic reticulum lectin 1 JBrowse link 14 115,314,890 115,352,871 RGD:1624291
G Os9 OS9, endoplasmic reticulum lectin JBrowse link 7 70,378,625 70,407,135 RGD:1624291
G Svip small VCP interacting protein JBrowse link 1 107,368,117 107,373,807 RGD:1624291
G Ubac2 UBA domain containing 2 JBrowse link 15 108,286,407 108,433,531 RGD:1624291
G Ube2g2 ubiquitin-conjugating enzyme E2G 2 JBrowse link 20 11,700,089 11,721,823 RGD:1624291
G Ube2j1 ubiquitin-conjugating enzyme E2, J1 JBrowse link 5 48,274,387 48,292,699 RGD:1624291
G Yod1 YOD1 deubiquitinase JBrowse link 13 47,441,296 47,443,013 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    cellular process 18362
      negative regulation of cellular process 5082
        negative regulation of response to endoplasmic reticulum stress 50
          negative regulation of ERAD pathway 14
            negative regulation of ER-associated ubiquitin-dependent protein catabolic process 3
            negative regulation of retrograde protein transport, ER to cytosol 9
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      catabolic process 2481
        organic substance catabolic process 2039
          macromolecule catabolic process 1309
            cellular macromolecule catabolic process 1097
              cellular protein catabolic process 804
                proteolysis involved in cellular protein catabolic process 751
                  regulation of proteolysis involved in cellular protein catabolic process 226
                    regulation of proteasomal protein catabolic process 192
                      regulation of ERAD pathway 29
                        negative regulation of ERAD pathway 14
                          negative regulation of ER-associated ubiquitin-dependent protein catabolic process 3
                          negative regulation of retrograde protein transport, ER to cytosol 9
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.