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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of ERAD pathway
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Accession:GO:1904294 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of ERAD pathway.
Synonyms:exact_synonym: positive regulation of endoplasmic reticulum-associated degradation;   up regulation of ERAD pathway;   up regulation of endoplasmic reticulum-associated degradation;   upregulation of ERAD pathway;   upregulation of endoplasmic reticulum-associated degradation
 narrow_synonym: activation of ERAD pathway;   activation of endoplasmic reticulum-associated degradation
 related_synonym: activation of ER-associated degradation pathway;   activation of endoplasmic reticulum-associated protein degradation pathway;   positive regulation of ER-associated degradation pathway;   positive regulation of endoplasmic reticulum-associated protein degradation pathway;   up regulation of ER-associated degradation pathway;   up regulation of endoplasmic reticulum-associated protein degradation pathway;   upregulation of ER-associated degradation pathway;   upregulation of endoplasmic reticulum-associated protein degradation pathway


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positive regulation of ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Atxn3 ataxin 3 JBrowse link 6 125,817,420 125,853,461 RGD:1624291
G Bag6 BAG cochaperone 6 JBrowse link 20 5,124,512 5,138,084 RGD:1624291
G Rnf185 ring finger protein 185 JBrowse link 14 83,648,400 83,685,273 RGD:1600115
RGD:1624291
G Rnft1 ring finger protein, transmembrane 1 JBrowse link 10 73,807,455 73,821,178 RGD:1624291
G Tmem259 transmembrane protein 259 JBrowse link 7 12,771,239 12,777,901 RGD:1624291
RGD:13792537
G Tmem67 transmembrane protein 67 JBrowse link 5 25,666,138 25,721,056 RGD:8554391
G Usp13 ubiquitin specific peptidase 13 JBrowse link 2 119,197,153 119,317,507 RGD:1624291
positive regulation of ER-associated ubiquitin-dependent protein catabolic process term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
G Cav1 caveolin 1 JBrowse link 4 44,597,123 44,630,206 RGD:1600115
RGD:1624291
G Herpud1 homocysteine inducible ER protein with ubiquitin like domain 1 JBrowse link 19 11,046,905 11,057,440 RGD:10047316
RGD:1624291
G Sgta small glutamine rich tetratricopeptide repeat containing alpha JBrowse link 7 11,521,949 11,538,691 RGD:1624291
G Ubqln1 ubiquilin 1 JBrowse link 17 6,840,441 6,878,842 RGD:1600115
RGD:1624291
G Ubqln2 ubiquilin 2 JBrowse link X 18,723,313 18,726,732 RGD:1624291
positive regulation of retrograde protein transport, ER to cytosol term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bcap31 B-cell receptor-associated protein 31 JBrowse link X 157,094,365 157,126,397 RGD:1624291
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1624291
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 3 151,232,741 151,258,559 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    cellular process 18362
      positive regulation of cellular process 6025
        positive regulation of response to endoplasmic reticulum stress 35
          positive regulation of ERAD pathway 15
            positive regulation of ER-associated ubiquitin-dependent protein catabolic process 6
            positive regulation of retrograde protein transport, ER to cytosol 3
Path 2
Term Annotations click to browse term
  biological_process 19578
    metabolic process 11901
      catabolic process 2481
        organic substance catabolic process 2039
          macromolecule catabolic process 1309
            cellular macromolecule catabolic process 1097
              cellular protein catabolic process 804
                proteolysis involved in cellular protein catabolic process 751
                  regulation of proteolysis involved in cellular protein catabolic process 226
                    regulation of proteasomal protein catabolic process 192
                      regulation of ERAD pathway 29
                        positive regulation of ERAD pathway 15
                          positive regulation of ER-associated ubiquitin-dependent protein catabolic process 6
                          positive regulation of retrograde protein transport, ER to cytosol 3
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.