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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of telomere maintenance via telomere lengthening
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Accession:GO:1904357 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of telomere maintenance via telomere lengthening.
Synonyms:exact_synonym: down regulation of telomere maintenance via telomere lengthening;   downregulation of telomere maintenance via telomere lengthening
 narrow_synonym: inhibition of telomere maintenance via telomere lengthening


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negative regulation of telomere maintenance via telomere lengthening term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ercc4 ERCC excision repair 4, endonuclease catalytic subunit JBrowse link 10 2,010,140 2,037,953 RGD:1624291
G Mcrs1 microspherule protein 1 JBrowse link 7 140,910,420 140,919,234 RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1624291
G Slx1b SLX1 homolog B, structure-specific endonuclease subunit JBrowse link 1 198,114,514 198,120,061 RGD:1624291
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tnks tankyrase JBrowse link 16 60,925,093 61,067,192 RGD:1624291
G Tnks2 tankyrase 2 RGD:1624291
negative regulation of telomere maintenance via telomerase term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Acd ACD, shelterin complex subunit and telomerase recruitment factor JBrowse link 19 37,665,289 37,668,043 RGD:1624291
RGD:13792537
G Ctc1 CST telomere replication complex component 1 JBrowse link 10 55,596,172 55,616,873 RGD:1624291
G Dcp2 decapping mRNA 2 JBrowse link 18 35,489,274 35,671,676 RGD:1624291
G Exosc10 exosome component 10 JBrowse link 5 165,374,964 165,398,195 RGD:1624291
G Gnl3l G protein nucleolar 3 like JBrowse link X 20,037,558 20,070,505 RGD:1624291
G Hnrnpa1 heterogeneous nuclear ribonucleoprotein A1 JBrowse link 7 144,865,302 144,871,592 RGD:1624291
RGD:1600115
G Hnrnpc heterogeneous nuclear ribonucleoprotein C JBrowse link 15 28,486,605 28,517,353 RGD:1624291
G Hnrnpu heterogeneous nuclear ribonucleoprotein U JBrowse link 13 96,222,093 96,238,845 RGD:1624291
RGD:13792537
RGD:1600115
G Nat10 N-acetyltransferase 10 JBrowse link 3 93,658,119 93,698,136 RGD:1624291
G Pif1 PIF1 5'-to-3' DNA helicase JBrowse link 8 71,124,477 71,133,460 RGD:1624291
G Pinx1 PIN2/TERF1 interacting, telomerase inhibitor 1 JBrowse link 15 47,211,682 47,270,343 RGD:1624291
G Pml promyelocytic leukemia JBrowse link 8 63,002,515 63,034,310 RGD:1624291
G Pot1 protection of telomeres 1 JBrowse link 4 51,888,632 51,946,764 RGD:1624291
G Src SRC proto-oncogene, non-receptor tyrosine kinase JBrowse link 3 153,547,807 153,595,643 RGD:1624291
G Stn1 STN1 subunit of CST complex JBrowse link 1 267,281,786 267,315,714 RGD:1600115
RGD:1624291
G Ten1 TEN1 subunit of CST complex JBrowse link 10 105,073,077 105,095,094 RGD:1624291
RGD:13792537
G Tent4b terminal nucleotidyltransferase 4B JBrowse link 19 19,771,289 19,834,759 RGD:1624291
G Terf1 telomeric repeat binding factor 1 JBrowse link 5 2,853,455 2,882,731 RGD:1624291
G Terf2 telomeric repeat binding factor 2 JBrowse link 19 39,271,992 39,301,506 RGD:1624291
G Tinf2 TERF1 interacting nuclear factor 2 JBrowse link 15 34,358,697 34,365,085 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19575
    biological regulation 13535
      regulation of biological quality 4287
        regulation of telomere maintenance 83
          negative regulation of telomere maintenance 37
            negative regulation of telomere maintenance via telomere lengthening 27
              negative regulation of telomere maintenance via telomerase 20
Path 2
Term Annotations click to browse term
  biological_process 19575
    metabolic process 11899
      cellular metabolic process 10737
        cellular aromatic compound metabolic process 5503
          nucleobase-containing compound metabolic process 5276
            nucleic acid metabolic process 4782
              DNA metabolic process 887
                telomere maintenance 126
                  regulation of telomere maintenance 83
                    negative regulation of telomere maintenance 37
                      negative regulation of telomere maintenance via telomere lengthening 27
                        negative regulation of telomere maintenance via telomerase 20
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.