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ONTOLOGY REPORT - ANNOTATIONS


Term:mannose trimming involved in glycoprotein ERAD pathway
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Accession:GO:1904382 term browser browse the term
Definition:The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
Synonyms:exact_synonym: protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation;   protein alpha-1,2-demannosylation involved in glycoprotein ERAD;   protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway;   protein alpha-1,2-demannosylation involved in gpERAD
 broad_synonym: mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process
 related_synonym: glycoprotein mannose trimming involved in ER-associated glycoprotein degradation;   glycoprotein mannose trimming involved in glycoprotein ERAD;   glycoprotein mannose trimming involved in glycoprotein ERAD pathway;   glycoprotein mannose trimming involved in gpERAD


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mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 4 140,886,644 140,918,654 RGD:1624291
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 3 151,232,741 151,258,559 RGD:1624291
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 JBrowse link 13 69,135,095 69,197,708 RGD:1624291
G Man1b1 mannosidase, alpha, class 1B, member 1 JBrowse link 3 2,547,259 2,569,051 RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19439
    response to stimulus 10457
      response to chemical 6380
        response to oxygen-containing compound 2323
          response to glycoprotein 11
            ubiquitin-dependent glycoprotein ERAD pathway 4
              mannose trimming involved in glycoprotein ERAD pathway 4
Path 2
Term Annotations click to browse term
  biological_process 19439
    metabolic process 11641
      organic substance metabolic process 11030
        macromolecule metabolic process 9494
          macromolecule catabolic process 1296
            protein catabolic process 958
              cellular protein catabolic process 793
                proteolysis involved in cellular protein catabolic process 741
                  modification-dependent protein catabolic process 629
                    ubiquitin-dependent protein catabolic process 618
                      proteasome-mediated ubiquitin-dependent protein catabolic process 409
                        ubiquitin-dependent ERAD pathway 75
                          ubiquitin-dependent glycoprotein ERAD pathway 4
                            mannose trimming involved in glycoprotein ERAD pathway 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.