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ONTOLOGY REPORT - ANNOTATIONS


Term:mannose trimming involved in glycoprotein ERAD pathway
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Accession:GO:1904382 term browser browse the term
Definition:The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
Synonyms:exact_synonym: protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation;   protein alpha-1,2-demannosylation involved in glycoprotein ERAD;   protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway;   protein alpha-1,2-demannosylation involved in gpERAD
 broad_synonym: mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process
 related_synonym: glycoprotein mannose trimming involved in ER-associated glycoprotein degradation;   glycoprotein mannose trimming involved in glycoprotein ERAD;   glycoprotein mannose trimming involved in glycoprotein ERAD pathway;   glycoprotein mannose trimming involved in gpERAD


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mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Edem1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link NW_004955421 8,196,631 8,225,561 RGD:9068941
G Edem2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link NW_004955422 26,243,034 26,271,849 RGD:9068941
G Edem3 ER degradation enhancing alpha-mannosidase like protein 3 JBrowse link NW_004955406 23,329,400 23,401,282 RGD:9068941
G Man1b1 mannosidase alpha class 1B member 1 JBrowse link NW_004955513 5,109,651 5,122,568 RGD:9068941

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14568
    response to stimulus 7786
      response to chemical 4035
        response to oxygen-containing compound 1572
          response to glycoprotein 6
            ubiquitin-dependent glycoprotein ERAD pathway 4
              mannose trimming involved in glycoprotein ERAD pathway 4
Path 2
Term Annotations click to browse term
  biological_process 14568
    metabolic process 9957
      organic substance metabolic process 9462
        macromolecule metabolic process 8144
          macromolecule catabolic process 1366
            protein catabolic process 901
              cellular protein catabolic process 743
                proteolysis involved in cellular protein catabolic process 688
                  modification-dependent protein catabolic process 600
                    ubiquitin-dependent protein catabolic process 594
                      proteasome-mediated ubiquitin-dependent protein catabolic process 414
                        ubiquitin-dependent ERAD pathway 78
                          ubiquitin-dependent glycoprotein ERAD pathway 4
                            mannose trimming involved in glycoprotein ERAD pathway 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.