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ONTOLOGY REPORT - ANNOTATIONS


Term:mannose trimming involved in glycoprotein ERAD pathway
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Accession:GO:1904382 term browser browse the term
Definition:The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
Synonyms:exact_synonym: protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation;   protein alpha-1,2-demannosylation involved in glycoprotein ERAD;   protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway;   protein alpha-1,2-demannosylation involved in gpERAD
 broad_synonym: mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process
 related_synonym: glycoprotein mannose trimming involved in ER-associated glycoprotein degradation;   glycoprotein mannose trimming involved in glycoprotein ERAD;   glycoprotein mannose trimming involved in glycoprotein ERAD pathway;   glycoprotein mannose trimming involved in gpERAD


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mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 3 5,187,707 5,219,963 RGD:2290271
G EDEM2 ER degradation enhancing alpha-mannosidase like protein 2 JBrowse link 20 35,115,364 35,147,336 RGD:2290271
G EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 JBrowse link 1 184,690,237 184,754,907 RGD:2290271
G MAN1B1 mannosidase alpha class 1B member 1 JBrowse link 9 137,086,941 137,109,183 RGD:2290271

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18019
    response to stimulus 9495
      response to chemical 4908
        response to oxygen-containing compound 1734
          response to glycoprotein 6
            ubiquitin-dependent glycoprotein ERAD pathway 4
              mannose trimming involved in glycoprotein ERAD pathway 4
Path 2
Term Annotations click to browse term
  biological_process 18019
    metabolic process 11613
      organic substance metabolic process 11030
        macromolecule metabolic process 9498
          macromolecule catabolic process 1465
            protein catabolic process 978
              cellular protein catabolic process 808
                proteolysis involved in cellular protein catabolic process 749
                  modification-dependent protein catabolic process 657
                    ubiquitin-dependent protein catabolic process 651
                      proteasome-mediated ubiquitin-dependent protein catabolic process 434
                        ubiquitin-dependent ERAD pathway 80
                          ubiquitin-dependent glycoprotein ERAD pathway 4
                            mannose trimming involved in glycoprotein ERAD pathway 4
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.