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ONTOLOGY REPORT - ANNOTATIONS


Term:mannose trimming involved in glycoprotein ERAD pathway
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Accession:GO:1904382 term browser browse the term
Definition:The removal of one or more alpha 1,2-linked mannose residues from a mannosylated protein that occurs as part of glycoprotein ER-associated glycoprotein degradation (gpERAD).
Synonyms:exact_synonym: protein alpha-1,2-demannosylation involved in ER-associated glycoprotein degradation;   protein alpha-1,2-demannosylation involved in glycoprotein ERAD;   protein alpha-1,2-demannosylation involved in glycoprotein ERAD pathway;   protein alpha-1,2-demannosylation involved in gpERAD
 broad_synonym: mannose trimming involved in misfolded or incompletely synthesized glycoprotein catabolic process
 related_synonym: glycoprotein mannose trimming involved in ER-associated glycoprotein degradation;   glycoprotein mannose trimming involved in glycoprotein ERAD;   glycoprotein mannose trimming involved in glycoprotein ERAD pathway;   glycoprotein mannose trimming involved in gpERAD


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mannose trimming involved in glycoprotein ERAD pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G EDEM1 ER degradation enhancing alpha-mannosidase like protein 1 JBrowse link 13 61,703,601 61,732,231 RGD:14298760
G EDEM3 ER degradation enhancing alpha-mannosidase like protein 3 JBrowse link 9 125,908,861 125,983,073 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 14973
    response to stimulus 7049
      response to chemical 3796
        response to oxygen-containing compound 907
          response to glycoprotein 3
            ubiquitin-dependent glycoprotein ERAD pathway 2
              mannose trimming involved in glycoprotein ERAD pathway 2
Path 2
Term Annotations click to browse term
  biological_process 14973
    metabolic process 9064
      organic substance metabolic process 8517
        macromolecule metabolic process 7322
          macromolecule catabolic process 990
            protein catabolic process 740
              cellular protein catabolic process 616
                proteolysis involved in cellular protein catabolic process 579
                  modification-dependent protein catabolic process 503
                    ubiquitin-dependent protein catabolic process 493
                      proteasome-mediated ubiquitin-dependent protein catabolic process 314
                        ubiquitin-dependent ERAD pathway 67
                          ubiquitin-dependent glycoprotein ERAD pathway 2
                            mannose trimming involved in glycoprotein ERAD pathway 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.