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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of tumor necrosis factor secretion
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Accession:GO:1904468 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of tumor necrosis factor secretion.
Synonyms:exact_synonym: down regulation of TNF secretion;   down regulation of TNF superfamily, member 2 secretion;   down regulation of TNF-alpha secretion;   down regulation of Tnfa secretion;   down regulation of cachectin secretion;   down regulation of tumor necrosis factor alpha secretion;   down regulation of tumor necrosis factor ligand superfamily member 2 secretion;   down regulation of tumor necrosis factor secretion;   downregulation of TNF secretion;   downregulation of TNF superfamily, member 2 secretion;   downregulation of TNF-alpha secretion;   downregulation of Tnfa secretion;   downregulation of cachectin secretion;   downregulation of tumor necrosis factor alpha secretion;   downregulation of tumor necrosis factor ligand superfamily member 2 secretion;   downregulation of tumor necrosis factor secretion;   negative regulation of TNF secretion;   negative regulation of TNF superfamily, member 2 secretion;   negative regulation of TNF-alpha secretion;   negative regulation of Tnfa secretion;   negative regulation of cachectin secretion;   negative regulation of tumor necrosis factor alpha secretion;   negative regulation of tumor necrosis factor ligand superfamily member 2 secretion
 narrow_synonym: inhibition of TNF secretion;   inhibition of TNF superfamily, member 2 secretion;   inhibition of TNF-alpha secretion;   inhibition of Tnfa secretion;   inhibition of cachectin secretion;   inhibition of tumor necrosis factor alpha secretion;   inhibition of tumor necrosis factor ligand superfamily member 2 secretion;   inhibition of tumor necrosis factor secretion


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negative regulation of tumor necrosis factor secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Cx3cl1 C-X3-C motif chemokine ligand 1 JBrowse link 19 10,644,267 10,654,861 RGD:1600115
RGD:1624291
G Ghrl ghrelin and obestatin prepropeptide JBrowse link 4 145,674,157 145,678,066 RGD:12905041
G Ghsr growth hormone secretagogue receptor JBrowse link 2 113,065,953 113,071,265 RGD:12907501
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1600115
RGD:1624291
G Nr1h4 nuclear receptor subfamily 1, group H, member 4 JBrowse link 7 30,003,429 30,162,095 RGD:1600115
RGD:1624291
G Ptger4 prostaglandin E receptor 4 JBrowse link 2 54,951,625 54,966,470 RGD:10043380
G Syt11 synaptotagmin 11 JBrowse link 2 188,112,301 188,138,180 RGD:1624291
RGD:1600115
G Tlr6 toll-like receptor 6 JBrowse link 14 45,024,351 45,041,188 RGD:1624291
G Zc3h12a zinc finger CCCH type containing 12A JBrowse link 5 143,111,342 143,120,131 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    multicellular organismal process 8629
      cytokine production 781
        negative regulation of cytokine production 270
          negative regulation of cytokine secretion 68
            negative regulation of tumor necrosis factor secretion 10
Path 2
Term Annotations click to browse term
  biological_process 18166
    localization 6061
      establishment of localization 4655
        transport 4517
          nitrogen compound transport 2185
            amide transport 1867
              peptide transport 1834
                peptide secretion 687
                  protein secretion 634
                    cytokine secretion 260
                      regulation of cytokine secretion 230
                        negative regulation of cytokine secretion 68
                          negative regulation of tumor necrosis factor secretion 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.