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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of ubiquitin protein ligase activity
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Accession:GO:1904667 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of ubiquitin protein ligase activity.
Synonyms:exact_synonym: down regulation of protein ubiquitination activity;   down regulation of ubiquitin ligase activity;   down regulation of ubiquitin protein ligase activity;   downregulation of protein ubiquitination activity;   downregulation of ubiquitin ligase activity;   downregulation of ubiquitin protein ligase activity;   negative regulation of protein ubiquitination activity;   negative regulation of ubiquitin ligase activity
 narrow_synonym: inhibition of protein ubiquitination activity;   inhibition of ubiquitin ligase activity;   inhibition of ubiquitin protein ligase activity;   negative regulation of APC-Cdc20 complex activity;   negative regulation of APC-fizzy related complex activity
 related_synonym: down regulation of E3;   downregulation of E3;   inhibition of E3;   negative regulation of APC activity during mitotic cell cycle;   negative regulation of APC/C activity during mitotic cell cycle;   negative regulation of E3;   negative regulation of anaphase-promoting complex activity during mitotic cell cycle;   negative regulation of cyclosome activity during mitotic cell cycle;   negative regulation of mitotic anaphase-promoting complex activity
 alt_id: GO:0060564;   GO:1904190


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negative regulation of ubiquitin protein ligase activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bag2 BAG cochaperone 2 ISO (PMID:16207813) RGD PMID:16207813 NCBI chr 9:38,456,487...38,467,120
Ensembl chr 9:38,456,468...38,467,118
JBrowse link
G Cdkn2a cyclin-dependent kinase inhibitor 2A ISO (PMID:18560357) RGD PMID:18560357 NCBI chr 5:107,823,323...107,832,405
Ensembl chr 5:107,823,330...107,841,175
JBrowse link
G Fbxo5 F-box protein 5 ISO (PMID:11988738), (PMID:16921029), (PMID:23708605), (PMID:29875408) RGD PMID:11988738, PMID:16921029, PMID:23708605, PMID:29875408 NCBI chr 1:42,461,277...42,467,646
Ensembl chr 1:42,461,291...42,467,586
JBrowse link
G Mad2l1 mitotic arrest deficient 2 like 1 ISO (PMID:11459825) RGD PMID:11459825 NCBI chr 4:97,530,993...97,543,179
Ensembl chr 4:97,531,083...97,537,086
JBrowse link
G Mad2l2 mitotic arrest deficient 2 like 2 ISO
ISS
(PMID:11459826)
GO_REF:0000024
RGD
UniProt
PMID:11459826 GO_REF:0000024 NCBI chr 5:164,943,183...164,956,255
Ensembl chr 5:164,950,917...164,956,255
JBrowse link
G Rpl11 ribosomal protein L11 ISO (PMID:18560357) RGD PMID:18560357 NCBI chr 5:154,390,809...154,394,412
Ensembl chr 5:154,388,140...154,394,328
JBrowse link
G Rpl23 ribosomal protein L23 ISO (PMID:15314173) RGD PMID:15314173 NCBI chr10:85,721,398...85,725,359
Ensembl chr10:85,721,394...85,725,429
JBrowse link
G Rpl5 ribosomal protein L5 ISO (PMID:18560357) RGD PMID:18560357 NCBI chr14:2,860,963...2,867,397
Ensembl chr14:2,860,965...2,867,397
JBrowse link
G Rps7 ribosomal protein S7 ISO (PMID:17310983) RGD PMID:17310983 NCBI chr 6:47,899,525...47,904,389
Ensembl chr 6:47,899,525...47,904,437
JBrowse link
G Usp44 ubiquitin specific peptidase 44 ISO (PMID:17443180) RGD PMID:17443180 NCBI chr 7:34,714,293...34,759,352
Ensembl chr 7:34,744,483...34,759,206
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20027
    biological regulation 13773
      regulation of molecular function 3077
        regulation of catalytic activity 2344
          regulation of transferase activity 1001
            regulation of ubiquitin-protein transferase activity 53
              negative regulation of ubiquitin-protein transferase activity 19
                negative regulation of ubiquitin protein ligase activity 10
Path 2
Term Annotations click to browse term
  biological_process 20027
    metabolic process 12278
      organic substance metabolic process 11660
        macromolecule metabolic process 10098
          protein metabolic process 6264
            protein modification process 3949
              cellular protein modification process 3949
                protein modification by small protein conjugation or removal 952
                  protein modification by small protein conjugation 816
                    protein ubiquitination 767
                      regulation of protein ubiquitination 212
                        negative regulation of protein ubiquitination 84
                          negative regulation of ubiquitin-protein transferase activity 19
                            negative regulation of ubiquitin protein ligase activity 10
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.