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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of Wnt-Frizzled-LRP5/6 complex assembly
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Accession:GO:1904723 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of Wnt-Frizzled-LRP5/6 complex assembly.
Synonyms:exact_synonym: down regulation of Frizzled-LRP5/6 complex assembly;   down regulation of Wnt-FZD-LRP5/6 trimeric complex assembly;   down regulation of Wnt-FZD-LRP5/6 trimeric complex formation;   downregulation of Frizzled-LRP5/6 complex assembly;   downregulation of Wnt-FZD-LRP5/6 trimeric complex assembly;   downregulation of Wnt-FZD-LRP5/6 trimeric complex formation;   negative regulation of Wnt-FZD-LRP5/6 trimeric complex assembly;   negative regulation of Wnt-FZD-LRP5/6 trimeric complex formation
 narrow_synonym: down regulation of WNT-FZD-LRP5 complex assembly;   down regulation of WNT-FZD-LRP5 complex formation;   down regulation of WNT-FZD-LRP6 complex assembly;   down regulation of WNT-FZD-LRP6 complex formation;   downregulation of WNT-FZD-LRP5 complex assembly;   downregulation of WNT-FZD-LRP5 complex formation;   downregulation of WNT-FZD-LRP6 complex assembly;   downregulation of WNT-FZD-LRP6 complex formation;   inhibition of Frizzled-LRP5/6 complex assembly;   inhibition of WNT-FZD-LRP5 complex assembly;   inhibition of WNT-FZD-LRP5 complex formation;   inhibition of WNT-FZD-LRP6 complex assembly;   inhibition of WNT-FZD-LRP6 complex formation;   inhibition of Wnt-FZD-LRP5/6 trimeric complex assembly;   inhibition of Wnt-FZD-LRP5/6 trimeric complex formation;   negative regulation of WNT-FZD-LRP5 complex assembly;   negative regulation of WNT-FZD-LRP5 complex formation;   negative regulation of WNT-FZD-LRP6 complex assembly;   negative regulation of WNT-FZD-LRP6 complex formation
 related_synonym: down regulation of Frizzled-LRP5/6 complex formation;   down regulation of Wnt-induced Frizzled-LRP5/6 complex assembly;   down regulation of Wnt-induced Frizzled-LRP5/6 complex formation;   downregulation of Frizzled-LRP5/6 complex formation;   downregulation of Wnt-induced Frizzled-LRP5/6 complex assembly;   downregulation of Wnt-induced Frizzled-LRP5/6 complex formation;   inhibition of Frizzled-LRP5/6 complex formation;   inhibition of Wnt-induced Frizzled-LRP5/6 complex assembly;   inhibition of Wnt-induced Frizzled-LRP5/6 complex formation;   negative regulation of Frizzled-LRP5/6 complex assembly;   negative regulation of Frizzled-LRP5/6 complex formation;   negative regulation of Wnt-induced Frizzled-LRP5/6 complex assembly;   negative regulation of Wnt-induced Frizzled-LRP5/6 complex formation


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negative regulation of Wnt-Frizzled-LRP5/6 complex assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO UniProtKB:O75581 (PMID:11433302), (PMID:11448771), (PMID:20093360) RGD PMID:11433302, PMID:11448771, PMID:20093360 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    negative regulation of biological process 5686
      negative regulation of cellular process 5156
        negative regulation of cellular component organization 781
          negative regulation of protein-containing complex assembly 157
            negative regulation of Wnt-Frizzled-LRP5/6 complex assembly 1
Path 2
Term Annotations click to browse term
  biological_process 20028
    cellular process 18800
      cellular component organization or biogenesis 6789
        cellular component organization 6534
          protein-containing complex subunit organization 1813
            protein-containing complex assembly 1608
              regulation of protein-containing complex assembly 465
                regulation of Wnt-Frizzled-LRP5/6 complex assembly 1
                  negative regulation of Wnt-Frizzled-LRP5/6 complex assembly 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.