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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of interleukin-17 secretion
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Accession:GO:1905077 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of interleukin-17 secretion.
Comment:An example of this is IL23A in human (Q9NPF7) in PMID:16482511 (inferred from direct assay).
Synonyms:exact_synonym: down regulation of CTLA-8 secretion;   down regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion;   down regulation of IL-17 secretion;   down regulation of IL-17A secretion;   down regulation of IL17A secretion;   down regulation of interleukin-17 secretion;   downregulation of CTLA-8 secretion;   downregulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion;   downregulation of IL-17 secretion;   downregulation of IL-17A secretion;   downregulation of IL17A secretion;   downregulation of interleukin-17 secretion;   negative regulation of CTLA-8 secretion;   negative regulation of Cytotoxic T-lymphocyte-associated antigen 8 secretion;   negative regulation of IL-17 secretion;   negative regulation of IL-17A secretion;   negative regulation of IL17A secretion
 narrow_synonym: inhibition of CTLA-8 secretion;   inhibition of Cytotoxic T-lymphocyte-associated antigen 8 secretion;   inhibition of IL-17 secretion;   inhibition of IL-17A secretion;   inhibition of IL17A secretion;   inhibition of interleukin-17 secretion


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negative regulation of interleukin-17 secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Arg2 arginase 2 JBrowse link 6 102,311,097 102,338,406 RGD:1600115
RGD:1624291
G Il27ra interleukin 27 receptor subunit alpha JBrowse link 19 25,151,835 25,163,995 RGD:1600115
RGD:1624291
G Otud5 OTU deubiquitinase 5 JBrowse link X 15,471,212 15,504,372 RGD:1624291
G Parp1 poly (ADP-ribose) polymerase 1 JBrowse link 13 98,857,255 98,889,444 RGD:1624291
G Ubr5 ubiquitin protein ligase E3 component n-recognin 5 JBrowse link 7
7
76,789,110
76,839,661
76,835,517
76,907,441
RGD:1624291

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18166
    multicellular organismal process 8629
      cytokine production 781
        negative regulation of cytokine production 270
          negative regulation of interleukin-17 production 18
            negative regulation of interleukin-17 secretion 5
Path 2
Term Annotations click to browse term
  biological_process 18166
    localization 6061
      establishment of localization 4655
        transport 4517
          nitrogen compound transport 2185
            amide transport 1867
              peptide transport 1834
                protein transport 1777
                  protein secretion 634
                    regulation of protein secretion 517
                      negative regulation of protein secretion 150
                        negative regulation of cytokine secretion 68
                          negative regulation of interleukin-17 secretion 5
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.