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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of guanyl-nucleotide exchange factor activity
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Accession:GO:1905098 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of guanyl-nucleotide exchange factor activity.
Synonyms:exact_synonym: down regulation of GDP-dissociation stimulator activity;   down regulation of GDS;   down regulation of GEF;   down regulation of guanyl-nucleotide exchange factor activity;   down regulation of guanyl-nucleotide release factor activity;   down regulation of guanyl-nucleotide releasing factor;   downregulation of GDP-dissociation stimulator activity;   downregulation of GDS;   downregulation of GEF;   downregulation of guanyl-nucleotide exchange factor activity;   downregulation of guanyl-nucleotide release factor activity;   downregulation of guanyl-nucleotide releasing factor;   negative regulation of GDP-dissociation stimulator activity;   negative regulation of GDS;   negative regulation of GEF;   negative regulation of guanyl-nucleotide release factor activity;   negative regulation of guanyl-nucleotide releasing factor
 narrow_synonym: down regulation of GNRP;   downregulation of GNRP;   inhibition of GDP-dissociation stimulator activity;   inhibition of GDS;   inhibition of GEF;   inhibition of GNRP;   inhibition of guanyl-nucleotide exchange factor activity;   inhibition of guanyl-nucleotide release factor activity;   inhibition of guanyl-nucleotide releasing factor;   negative regulation of GNRP


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negative regulation of guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Eif2b1 eukaryotic translation initiation factor 2B, subunit 1 (alpha) ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 5:124,570,214...124,579,131
Ensembl chr 5:124,570,213...124,579,131
JBrowse link
G Eif2b4 eukaryotic translation initiation factor 2B, subunit 4 delta ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr 5:31,187,558...31,193,139
Ensembl chr 5:31,187,558...31,193,430
JBrowse link
G Eif2s1 eukaryotic translation initiation factor 2, subunit 1 alpha ISO RGD GO_REF:0000096, MGI:MGI:4417868 NCBI chr12:78,862,072...78,887,010
Ensembl chr12:78,861,819...78,887,010
JBrowse link
G Gpsm1 G-protein signalling modulator 1 (AGS3-like, C. elegans) ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 2:26,314,611...26,348,237
Ensembl chr 2:26,315,515...26,348,237
JBrowse link
G Met met proto-oncogene ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 6:17,463,349...17,573,980
Ensembl chr 6:17,463,800...17,573,980
JBrowse link
G Stmn1 stathmin 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 4:134,468,320...134,473,843
Ensembl chr 4:134,468,320...134,473,843
JBrowse link
negative regulation of Rho guanyl-nucleotide exchange factor activity term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Ripor1 RHO family interacting cell polarization regulator 1 ISO MGI GO_REF:0000096, MGI:MGI:4834177 NCBI chr 8:105,594,087...105,622,219
Ensembl chr 8:105,605,255...105,622,219
JBrowse link
G Ripor2 RHO family interacting cell polarization regulator 2 IMP
ISO
(MGI:MGI:5887189|PMID:25588844) UniProtKB
MGI
PMID:25588844 GO_REF:0000096, MGI:MGI:4834177, MGI:MGI:5887189 NCBI chr13:24,501,524...24,733,806
Ensembl chr13:24,501,525...24,733,816
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 23369
    negative regulation of biological process 5690
      negative regulation of guanyl-nucleotide exchange factor activity 8
        negative regulation of Rho guanyl-nucleotide exchange factor activity 2
Path 2
Term Annotations click to browse term
  biological_process 23369
    biological regulation 13071
      regulation of molecular function 2714
        regulation of binding 413
          regulation of protein binding 238
            negative regulation of protein binding 113
              negative regulation of guanyl-nucleotide exchange factor activity 8
                negative regulation of Rho guanyl-nucleotide exchange factor activity 2
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.