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ONTOLOGY REPORT - ANNOTATIONS


Term:regulation of cardiocyte differentiation
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Accession:GO:1905207 term browser browse the term
Definition:Any process that modulates the frequency, rate or extent of cardiocyte differentiation.
Synonyms:exact_synonym: regulation of cardiac cell differentiation;   regulation of heart cell differentiation


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negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 ISO
ISS
(PMID:18545679)
GO_REF:0000024
RGD
UniProt
PMID:18545679 GO_REF:0000024 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dll1 delta like canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(MGI:5902683|PMID:18371447)
Ensembl
RGD
PMID:18371447 GO_REF:0000107, MGI:5902683 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 ISO UniProtKB:O75084 (PMID:23939491) RGD PMID:23939491 NCBI chr 7:60,128,506...60,210,482
Ensembl chr 7:60,128,508...60,210,518
JBrowse link
G Fzd7 frizzled class receptor 7 ISO UniProtKB:Q8WU20 (PMID:23939491) RGD PMID:23939491 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
G Hdac3 histone deacetylase 3 ISO (MGI:5571645|PMID:24565863) RGD PMID:24565863 MGI:5571645 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Sox6 SRY-box transcription factor 6 ISO (PMID:20081117) RGD PMID:20081117 NCBI chr 1:185,631,702...186,186,192
Ensembl chr 1:185,673,177...186,182,829
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prickle1 prickle planar cell polarity protein 1 IEA
ISO
GO_REF:0000107
(PMID:21199191)
Ensembl
RGD
PMID:21199191 GO_REF:0000107 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 IEA
ISO
GO_REF:0000107
(MGI:3689643|PMID:16151019)
Ensembl
RGD
PMID:16151019 GO_REF:0000107, MGI:3689643 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
negative regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klf5 Kruppel-like factor 5 IDA PMID:19542014 BHF-UCL PMID:19542014 RGD:13210556 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
negative regulation of cardiocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO (PMID:23069713) RGD PMID:23069713 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 ISO (MGI:5784966|PMID:24974728) RGD PMID:24974728 MGI:5784966 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Efnb2 ephrin B2 ISO (MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:3701380 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (MGI:5315691|PMID:18545679) RGD PMID:18545679 MGI:5315691 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO (MGI:5784966|PMID:24974728) RGD PMID:24974728 MGI:5784966 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Kat2a lysine acetyltransferase 2A IMP RGD PMID:20835911 RGD:8693751 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Mef2c myocyte enhancer factor 2C IEA
ISO
ISS
GO_REF:0000107
(PMID:9857019)
GO_REF:0000024
(MGI:3830899|PMID:16680724)
Ensembl
RGD
UniProt
PMID:9857019, PMID:16680724 GO_REF:0000024, GO_REF:0000107, MGI:3830899 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Myocd myocardin ISO
IEA
(PMID:18451334)
GO_REF:0000107
RGD
Ensembl
PMID:18451334 GO_REF:0000107 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
G Nrg1 neuregulin 1 IEA
ISO
GO_REF:0000107
(MGI:3701380|PMID:17336907)
Ensembl
RGD
PMID:17336907 GO_REF:0000107, MGI:3701380 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (PMID:25163461) RGD PMID:25163461 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Wnt3a Wnt family member 3A ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of cardiac muscle fiber development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO
ISS
IEA
(PMID:20702560)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:20702560 GO_REF:0000024, GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
positive regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 ISO
IEA
(PMID:23840305)
GO_REF:0000107
RGD
Ensembl
PMID:23840305 GO_REF:0000107 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Myocd myocardin IDA PMID:16151017 BHF-UCL PMID:16151017 RGD:8554320 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 ISS
ISO
GO_REF:0000024
(MGI:6201954|PMID:26489465)
UniProt
RGD
PMID:26489465 GO_REF:0000024, MGI:6201954 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Gata4 GATA binding protein 4 ISO (PMID:16137232) RGD PMID:16137232 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata6 GATA binding protein 6 ISO
IEA
(PMID:16137232)
GO_REF:0000107
RGD
Ensembl
PMID:16137232 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Nkx2-5 NK2 homeobox 5 IEA
ISO
GO_REF:0000107
(MGI:3784761|PMID:11889119)
Ensembl
RGD
PMID:11889119 GO_REF:0000107, MGI:3784761 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Tbx5 T-box transcription factor 5 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:11431700)
Ensembl
UniProt
RGD
PMID:11431700 GO_REF:0000024, GO_REF:0000107 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO
ISS
(PMID:15896309)
GO_REF:0000024
RGD
AgBase
PMID:15896309 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
regulation of cardiac cell fate specification term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Sox17 SRY-box transcription factor 17 ISO (MGI:3703823|PMID:17360443) RGD PMID:17360443 MGI:3703823 NCBI chr 5:14,890,318...14,895,907
Ensembl chr 5:14,890,408...14,895,907
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20020
    regulation of biological process 13071
      regulation of cellular process 12556
        regulation of cell differentiation 1684
          regulation of cardiocyte differentiation 30
            negative regulation of cardiocyte differentiation + 12
            positive regulation of cardiocyte differentiation + 18
            regulation of cardiac cell fate specification + 2
            regulation of cardiac muscle cell differentiation + 19
            regulation of cardiac vascular smooth muscle cell differentiation + 3
            regulation of cardioblast differentiation + 8
            regulation of endocardial cushion cell differentiation + 0
Path 2
Term Annotations click to browse term
  biological_process 20020
    developmental process 6826
      anatomical structure development 6268
        multicellular organism development 5743
          system development 5279
            animal organ development 4033
              heart development 687
                cardiocyte differentiation 180
                  regulation of cardiocyte differentiation 30
                    negative regulation of cardiocyte differentiation + 12
                    positive regulation of cardiocyte differentiation + 18
                    regulation of cardiac cell fate specification + 2
                    regulation of cardiac muscle cell differentiation + 19
                    regulation of cardiac vascular smooth muscle cell differentiation + 3
                    regulation of cardioblast differentiation + 8
                    regulation of endocardial cushion cell differentiation + 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.