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ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of cardiocyte differentiation
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Accession:GO:1905208 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of cardiocyte differentiation.
Synonyms:exact_synonym: down regulation of cardiac cell differentiation;   down regulation of cardiocyte differentiation;   down regulation of heart cell differentiation;   downregulation of cardiac cell differentiation;   downregulation of cardiocyte differentiation;   downregulation of heart cell differentiation;   negative regulation of cardiac cell differentiation;   negative regulation of heart cell differentiation
 narrow_synonym: inhibition of cardiac cell differentiation;   inhibition of cardiocyte differentiation;   inhibition of heart cell differentiation


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negative regulation of cardiocyte differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Egfr epidermal growth factor receptor ISO (PMID:23069713) RGD PMID:23069713 NCBI chr14:99,919,485...100,104,136
Ensembl chr14:99,919,485...100,098,796
JBrowse link
negative regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
negative regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp2 bone morphogenetic protein 2 ISO
ISS
(PMID:18545679)
GO_REF:0000024
RGD
UniProt
PMID:18545679 GO_REF:0000024 NCBI chr 3:126,335,963...126,346,771
Ensembl chr 3:126,335,863...126,346,318
JBrowse link
G Dkk1 dickkopf WNT signaling pathway inhibitor 1 ISO (PMID:20559569) RGD PMID:20559569 NCBI chr 1:248,952,896...248,956,579
Ensembl chr 1:248,895,738...248,898,607
JBrowse link
G Dll1 delta like canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:5902683|PMID:18371447)
Ensembl
RGD
PMID:18371447 GO_REF:0000107, MGI:MGI:5902683 NCBI chr 1:57,318,621...57,326,732
Ensembl chr 1:57,318,708...57,327,379
JBrowse link
G Frs2 fibroblast growth factor receptor substrate 2 ISO UniProtKB:O75084 (PMID:23939491) RGD PMID:23939491 NCBI chr 7:60,128,506...60,210,482
Ensembl chr 7:60,128,508...60,210,518
JBrowse link
G Fzd7 frizzled class receptor 7 ISO UniProtKB:Q8WU20 (PMID:23939491) RGD PMID:23939491 NCBI chr 9:66,305,731...66,308,550
Ensembl chr 9:66,305,731...66,308,550
JBrowse link
G Hdac3 histone deacetylase 3 ISO (MGI:MGI:5571645|PMID:24565863) RGD PMID:24565863 MGI:MGI:5571645 NCBI chr18:31,073,057...31,094,347
Ensembl chr18:31,073,058...31,094,303
JBrowse link
G Sox6 SRY-box transcription factor 6 ISO (PMID:20081117) RGD PMID:20081117 NCBI chr 1:185,631,702...186,186,192
Ensembl chr 1:185,673,177...186,182,829
JBrowse link
negative regulation of cardiac muscle cell myoblast differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Prickle1 prickle planar cell polarity protein 1 IEA
ISO
GO_REF:0000107
(PMID:21199191)
Ensembl
RGD
PMID:21199191 GO_REF:0000107 NCBI chr 7:134,702,964...134,799,437
Ensembl chr 7:134,702,964...134,722,215
JBrowse link
negative regulation of cardiac myofibril assembly term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Smad4 SMAD family member 4 ISO
IEA
(MGI:MGI:3689643|PMID:16151019)
GO_REF:0000107
RGD
Ensembl
PMID:16151019 GO_REF:0000107, MGI:MGI:3689643 NCBI chr18:69,626,682...69,657,373
Ensembl chr18:69,627,757...69,671,199
JBrowse link
negative regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Klf5 Kruppel-like factor 5 IDA PMID:19542014 BHF-UCL PMID:19542014 RGD:13210556 NCBI chr15:83,703,796...83,722,921
Ensembl chr15:83,703,791...83,722,921
JBrowse link
negative regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Cav3 caveolin 3 IMP RGD PMID:21170593 RGD:6784534 NCBI chr 4:144,382,945...144,398,919
Ensembl chr 4:144,382,945...144,398,917
JBrowse link
G Ctdp1 CTD phosphatase subunit 1 IMP RGD PMID:22569295 RGD:9686371 NCBI chr18:76,922,913...76,985,095
Ensembl chr18:76,922,934...76,984,203
JBrowse link
G Foxp1 forkhead box P1 IMP RGD PMID:26333362 RGD:11561912 NCBI chr 4:131,362,178...131,963,466
Ensembl chr 4:131,366,744...131,694,755
JBrowse link
G G6pd glucose-6-phosphate dehydrogenase IMP RGD PMID:24190878 RGD:10449133 NCBI chr  X:156,274,800...156,293,935
Ensembl chr  X:156,274,800...156,293,926
JBrowse link
G Gsk3a glycogen synthase kinase 3 alpha ISO (MGI:MGI:4829580|PMID:20516643) RGD PMID:20516643 MGI:MGI:4829580 NCBI chr 1:82,097,244...82,108,238
Ensembl chr 1:82,097,247...82,108,203
JBrowse link
G Mir451a microRNA 451a IMP RGD PMID:25209900 RGD:11558015 NCBI chr10:65,291,204...65,291,275
Ensembl chr10:65,291,204...65,291,275
JBrowse link
G Pak1 p21 (RAC1) activated kinase 1 IMP RGD PMID:22082674 RGD:11533929 NCBI chr 1:162,768,156...162,883,356
Ensembl chr 1:162,768,156...162,883,355
JBrowse link
G Pi16 peptidase inhibitor 16 ISO (MGI:MGI:3810223|PMID:17909105) RGD PMID:17909105 MGI:MGI:3810223 NCBI chr20:6,923,176...6,932,786
Ensembl chr20:6,923,489...6,932,786
JBrowse link
G Ppara peroxisome proliferator activated receptor alpha IMP RGD PMID:22198280 RGD:5687133 NCBI chr 7:126,618,872...126,687,282
Ensembl chr 7:126,619,196...126,681,752
JBrowse link
G Rgs2 regulator of G-protein signaling 2 IMP RGD PMID:16380388 RGD:13524577 NCBI chr13:60,846,458...60,849,061
Ensembl chr13:60,846,308...60,849,094
JBrowse link
G Rgs4 regulator of G-protein signaling 4 IDA RGD PMID:9918533 RGD:7207376 NCBI chr13:88,054,817...88,061,108
Ensembl chr13:88,054,817...88,061,108
JBrowse link
G Tomm70 translocase of outer mitochondrial membrane 70 IMP RGD PMID:25022898 RGD:13464131 NCBI chr11:45,477,053...45,511,409
Ensembl chr11:45,480,250...45,510,961
JBrowse link
G Yy1 YY1 transcription factor IMP RGD PMID:18632988 RGD:9588273 NCBI chr 6:132,702,443...132,726,848
Ensembl chr 6:132,702,448...132,727,046
JBrowse link
G Zfp418 zinc finger protein 418 ISO (MGI:MGI:5920524|PMID:29065170) RGD PMID:29065170 MGI:MGI:5920524 NCBI chr 1:69,615,413...69,629,997
Ensembl chr 1:69,615,434...69,629,913
JBrowse link
negative regulation of heart induction by canonical Wnt signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Wnt3a Wnt family member 3A ISO (PMID:19736317) RGD PMID:19736317 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    negative regulation of biological process 5710
      negative regulation of multicellular organismal process 1391
        negative regulation of cardiocyte differentiation 26
          negative regulation of cardiac cell fate specification + 1
          negative regulation of cardiac muscle cell differentiation + 22
          negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis 0
          negative regulation of cardiac vascular smooth muscle cell differentiation 1
          negative regulation of cardioblast differentiation + 2
          negative regulation of endocardial cushion cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            animal organ development 4027
              heart development 687
                cardiocyte differentiation 180
                  regulation of cardiocyte differentiation 65
                    negative regulation of cardiocyte differentiation 26
                      negative regulation of cardiac cell fate specification + 1
                      negative regulation of cardiac muscle cell differentiation + 22
                      negative regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis 0
                      negative regulation of cardiac vascular smooth muscle cell differentiation 1
                      negative regulation of cardioblast differentiation + 2
                      negative regulation of endocardial cushion cell differentiation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.