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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of cardiocyte differentiation
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Accession:GO:1905209 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of cardiocyte differentiation.
Synonyms:exact_synonym: positive regulation of cardiac cell differentiation;   positive regulation of heart cell differentiation;   up regulation of cardiac cell differentiation;   up regulation of cardiocyte differentiation;   up regulation of heart cell differentiation;   upregulation of cardiac cell differentiation;   upregulation of cardiocyte differentiation;   upregulation of heart cell differentiation
 narrow_synonym: activation of cardiac cell differentiation;   activation of cardiocyte differentiation;   activation of heart cell differentiation


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positive regulation of canonical Wnt signaling pathway involved in cardiac muscle cell fate commitment term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO MGI:MGI:3583755 (MGI:MGI:5432296|PMID:22711842) RGD PMID:22711842 MGI:MGI:5432296 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
positive regulation of cardiac muscle cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Arrb2 arrestin, beta 2 ISO (MGI:MGI:5784966|PMID:24974728) RGD PMID:24974728 MGI:MGI:5784966 NCBI chr10:57,040,252...57,048,045
Ensembl chr10:57,040,267...57,048,134
JBrowse link
G Efnb2 ephrin B2 ISO (MGI:MGI:3701380|PMID:17336907) RGD PMID:17336907 MGI:MGI:3701380 NCBI chr16:86,631,151...86,672,050
Ensembl chr16:86,631,064...86,675,049
JBrowse link
G Grem1 gremlin 1, DAN family BMP antagonist ISO (MGI:MGI:5315691|PMID:18545679) RGD PMID:18545679 MGI:MGI:5315691 NCBI chr 3:105,203,309...105,214,989
Ensembl chr 3:105,203,309...105,214,989
JBrowse link
G Gsk3b glycogen synthase kinase 3 beta ISO (MGI:MGI:5784966|PMID:24974728) RGD PMID:24974728 MGI:MGI:5784966 NCBI chr11:65,060,884...65,208,842
Ensembl chr11:65,066,235...65,209,268
JBrowse link
G Kat2a lysine acetyltransferase 2A IMP RGD PMID:20835911 RGD:8693751 NCBI chr10:88,611,586...88,619,558
Ensembl chr10:88,611,586...88,619,537
JBrowse link
G Mef2c myocyte enhancer factor 2C IEA
ISO
ISS
GO_REF:0000107
(PMID:9857019)
(MGI:MGI:3830899|PMID:16680724)
GO_REF:0000024
Ensembl
RGD
UniProt
PMID:9857019, PMID:16680724 GO_REF:0000024, GO_REF:0000107, MGI:MGI:3830899 NCBI chr 2:11,658,534...11,822,788
Ensembl chr 2:11,658,568...11,822,787
JBrowse link
G Myocd myocardin ISO
IEA
(PMID:18451334)
GO_REF:0000107
RGD
Ensembl
PMID:18451334 GO_REF:0000107 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
G Nrg1 neuregulin 1 ISO
IEA
(MGI:MGI:3701380|PMID:17336907)
GO_REF:0000107
RGD
Ensembl
PMID:17336907 GO_REF:0000107, MGI:MGI:3701380 NCBI chr16:62,969,573...64,065,063
Ensembl chr16:63,837,216...64,057,434
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (PMID:25163461) RGD PMID:25163461 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Wnt3a Wnt family member 3A ISO (PMID:20559569) RGD PMID:20559569 NCBI chr10:45,598,898...45,643,151
Ensembl chr10:45,598,912...45,638,035
JBrowse link
positive regulation of cardiac muscle fiber development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 ISO
ISS
IEA
(PMID:20702560)
GO_REF:0000024
GO_REF:0000107
RGD
UniProt
Ensembl
PMID:20702560 GO_REF:0000024, GO_REF:0000107 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
UniProtKB:P23359 (MGI:MGI:5502250|PMID:23863481)
Ensembl
RGD
PMID:23863481 GO_REF:0000107, MGI:MGI:5502250 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Bmp7 bone morphogenetic protein 7 ISO UniProtKB:P21275 (MGI:MGI:5502250|PMID:23863481) RGD PMID:23863481 MGI:MGI:5502250 NCBI chr 3:170,879,972...170,955,820
Ensembl chr 3:170,879,973...170,955,399
JBrowse link
G Sema3c semaphorin 3C ISO (MGI:MGI:5693177|PMID:26053665) RGD PMID:26053665 MGI:MGI:5693177 NCBI chr 4:14,318,276...14,490,438
Ensembl chr 4:14,318,274...14,490,446
JBrowse link
positive regulation of cardiac vascular smooth muscle cell differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gper1 G protein-coupled estrogen receptor 1 ISO
IEA
(PMID:23840305)
GO_REF:0000107
RGD
Ensembl
PMID:23840305 GO_REF:0000107 NCBI chr12:17,309,122...17,315,267
Ensembl chr12:17,309,834...17,311,112
JBrowse link
G Myocd myocardin IDA PMID:16151017 BHF-UCL PMID:16151017 RGD:8554320 NCBI chr10:51,682,053...51,781,458
Ensembl chr10:51,683,540...51,778,986
JBrowse link
positive regulation of cardioblast differentiation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Dhx36 DEAH-box helicase 36 ISS
ISO
GO_REF:0000024
(MGI:MGI:6201954|PMID:26489465)
UniProt
RGD
PMID:26489465 GO_REF:0000024, MGI:MGI:6201954 NCBI chr 2:152,785,844...152,824,549
Ensembl chr 2:152,785,844...152,824,547
JBrowse link
G Gata4 GATA binding protein 4 ISO (PMID:16137232) RGD PMID:16137232 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata6 GATA binding protein 6 ISO
IEA
(PMID:16137232)
GO_REF:0000107
RGD
Ensembl
PMID:16137232 GO_REF:0000107 NCBI chr18:2,415,821...2,447,087
Ensembl chr18:2,416,552...2,446,338
JBrowse link
G Nkx2-5 NK2 homeobox 5 ISO
IEA
(MGI:MGI:3784761|PMID:11889119)
GO_REF:0000107
RGD
Ensembl
PMID:11889119 GO_REF:0000107, MGI:MGI:3784761 NCBI chr10:16,635,989...16,638,758
Ensembl chr10:16,635,989...16,638,764
JBrowse link
G Tbx5 T-box transcription factor 5 IEA
ISS
ISO
GO_REF:0000107
GO_REF:0000024
(PMID:11431700)
Ensembl
UniProt
RGD
PMID:11431700 GO_REF:0000024, GO_REF:0000107 NCBI chr12:42,059,688...42,148,226
Ensembl chr12:42,097,626...42,148,146
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO
ISS
(PMID:15896309)
GO_REF:0000024
RGD
UniProt
PMID:15896309 GO_REF:0000024 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link
positive regulation of cell growth involved in cardiac muscle cell development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Adrb1 adrenoceptor beta 1 IMP RGD PMID:18194989 RGD:5129139 NCBI chr 1:277,537,585...277,538,985
Ensembl chr 1:277,537,585...277,538,985
JBrowse link
G Akap6 A-kinase anchoring protein 6 IMP
IDA
RGD PMID:21550986, PMID:16306226 RGD:6902940, RGD:2312613 NCBI chr 6:73,553,111...73,991,992
Ensembl chr 6:73,553,210...73,990,534
JBrowse link
G Ccn4 cellular communication network factor 4 IMP RGD PMID:21376054 RGD:5129173 NCBI chr 7:107,695,227...107,723,759
Ensembl chr 7:107,695,215...107,723,772
JBrowse link
G Ddx39b DExD-box helicase 39B IMP RGD PMID:20116367 RGD:10401141 NCBI chr20:4,806,103...4,818,600
Ensembl chr20:4,806,108...4,818,568
JBrowse link
G Edn1 endothelin 1 ISO RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217) RGD PMID:24117217 NCBI chr17:22,136,814...22,143,745
Ensembl chr17:22,137,324...22,143,324
JBrowse link
G Ep300 E1A binding protein p300 IMP RGD PMID:12724418 RGD:2312280 NCBI chr 7:122,818,194...122,889,055
Ensembl chr 7:122,818,975...122,861,296
JBrowse link
G Fdps farnesyl diphosphate synthase IMP RGD PMID:19716825 RGD:2316294 NCBI chr 2:188,403,595...188,413,219
Ensembl chr 2:188,392,858...188,413,219
JBrowse link
G Hamp hepcidin antimicrobial peptide IMP RGD PMID:24424338 RGD:11041632 NCBI chr 1:89,368,021...89,369,960
Ensembl chr 1:89,368,021...89,369,960
JBrowse link
G Igf1 insulin-like growth factor 1 ISO
IEA
RNAcentral:URS000006FDD4_9606|RNAcentral:URS000013D17D_9606 (PMID:24117217)
GO_REF:0000107
RGD
Ensembl
PMID:24117217 GO_REF:0000107 NCBI chr 7:28,412,123...28,491,815
Ensembl chr 7:28,412,198...28,486,609
JBrowse link
G Mtor mechanistic target of rapamycin kinase IMP RGD PMID:21318349, PMID:21933187 RGD:10040977, RGD:10040978 NCBI chr 5:165,263,813...165,373,967
Ensembl chr 5:165,263,800...165,373,967
JBrowse link
G Nr3c1 nuclear receptor subfamily 3, group C, member 1 IMP RGD PMID:22989630 RGD:7174736 NCBI chr18:31,728,373...32,704,022
Ensembl chr18:31,728,373...31,749,647
JBrowse link
G Parp2 poly (ADP-ribose) polymerase 2 IMP RGD PMID:23261455 RGD:13514044 NCBI chr15:27,739,416...27,749,650
Ensembl chr15:27,739,251...27,749,648
JBrowse link
G Pin1 peptidylprolyl cis/trans isomerase, NIMA-interacting 1 IMP RGD PMID:23487407 RGD:8693424 NCBI chr 8:21,669,236...21,680,615
Ensembl chr 8:21,669,236...21,680,615
JBrowse link
G Sirt1 sirtuin 1 IMP RGD PMID:25281201 RGD:13514043 NCBI chr20:26,831,971...26,851,587
Ensembl chr20:26,833,357...26,852,199
JBrowse link
G Slc25a4 solute carrier family 25 member 4 IDA RGD PMID:21325829 RGD:9681466 NCBI chr16:49,266,903...49,270,698
Ensembl chr16:49,266,903...49,270,698
JBrowse link
G Trip10 thyroid hormone receptor interactor 10 IMP RGD PMID:23915320 RGD:11535145 NCBI chr 9:9,689,214...9,702,353
Ensembl chr 9:9,689,475...9,702,306
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    positive regulation of biological process 6667
      positive regulation of multicellular organismal process 2063
        positive regulation of cardiocyte differentiation 37
          positive regulation of cardiac muscle cell differentiation + 28
          positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis 3
          positive regulation of cardiac vascular smooth muscle cell differentiation 2
          positive regulation of cardioblast differentiation + 6
          positive regulation of endocardial cushion cell differentiation 0
Path 2
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            animal organ development 4027
              heart development 687
                cardiocyte differentiation 180
                  regulation of cardiocyte differentiation 65
                    positive regulation of cardiocyte differentiation 37
                      positive regulation of cardiac muscle cell differentiation + 28
                      positive regulation of cardiac neural crest cell migration involved in outflow tract morphogenesis 3
                      positive regulation of cardiac vascular smooth muscle cell differentiation 2
                      positive regulation of cardioblast differentiation + 6
                      positive regulation of endocardial cushion cell differentiation 0
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.