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ONTOLOGY REPORT - ANNOTATIONS


Term:semi-lunar valve development
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Accession:GO:1905314 term browser browse the term
Definition:The process whose specific outcome is the progression of a semi-lunar valve over time, from its formation to the mature structure.
Synonyms:exact_synonym: semilunar valve development;   semilunar valves development


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semi-lunar valve development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 ISO (MGI:MGI:2429424|PMID:12441304), (MGI:MGI:3851675|PMID:19409885) RGD PMID:12441304, PMID:19409885 MGI:MGI:2429424, MGI:MGI:3851675 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
aortic valve development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 ISO GO:1905314 (MGI:MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:MGI:2429424 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:MGI:6158728 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (MGI:MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:MGI:3604925 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO
IEA
UniProtKB:P25119 (MGI:MGI:6158728|PMID:26491108)
GO_REF:0000107
RGD
Ensembl
PMID:26491108 GO_REF:0000107, MGI:MGI:6158728 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO UniProtKB:P25118 (MGI:MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:MGI:6158728 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
aortic valve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
(MGI:MGI:3039210|PMID:15070745), (MGI:MGI:3814273|PMID:18924235)
Ensembl
RGD
PMID:15070745, PMID:18924235 GO_REF:0000107, MGI:MGI:3039210, MGI:MGI:3814273 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Efna1 ephrin A1 ISO (MGI:MGI:4847981|PMID:20960543) RGD PMID:20960543 MGI:MGI:4847981 NCBI chr 2:188,588,808...188,596,156
Ensembl chr 2:188,588,796...188,596,222
JBrowse link
G Emilin1 elastin microfibril interfacer 1 ISO (MGI:MGI:5605894|PMID:25056700) RGD PMID:25056700 MGI:MGI:5605894 NCBI chr 6:26,821,249...26,829,013
Ensembl chr 6:26,821,255...26,828,972
JBrowse link
G Gata3 GATA binding protein 3 ISO
ISS
(MGI:MGI:3832106|PMID:18955134)
GO_REF:0000024
RGD
UniProt
PMID:18955134 GO_REF:0000024, MGI:MGI:3832106 NCBI chr17:72,419,752...72,452,043
Ensembl chr17:72,429,618...72,450,681
JBrowse link
G Gata4 GATA binding protein 4 ISO (PMID:29325903) RGD PMID:29325903 NCBI chr15:46,386,703...46,458,679
Ensembl chr15:46,386,712...46,432,965
JBrowse link
G Gata5 GATA binding protein 5 ISO (PMID:22641149), (PMID:24638895)
(MGI:MGI:5286818|PMID:21633169)
RGD PMID:21633169, PMID:22641149, PMID:24638895 MGI:MGI:5286818 NCBI chr 3:175,701,278...175,709,465
Ensembl chr 3:175,701,280...175,709,465
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 ISO MGI:MGI:2181762 (MGI:MGI:1197815|PMID:9515964) RGD PMID:9515964 MGI:MGI:1197815 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nos3 nitric oxide synthase 3 IEA
ISO
GO_REF:0000107
UniProtKB:Q01705 (MGI:MGI:3609262|PMID:10821808), (MGI:MGI:6158784|PMID:27107132), (MGI:MGI:6158885|PMID:23583836)
Ensembl
RGD
PMID:10821808, PMID:23583836, PMID:27107132 GO_REF:0000107, MGI:MGI:3609262, MGI:MGI:6158784, MGI:MGI:6158885 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 ISO (PMID:16025100), (PMID:17662764), (PMID:18593716)
UniProtKB:P70313 (MGI:MGI:6158728|PMID:26491108), (MGI:MGI:6158784|PMID:27107132), (MGI:MGI:6158885|PMID:23583836)
RGD PMID:16025100, PMID:17662764, PMID:18593716, PMID:23583836, PMID:26491108, PMID:27107132 MGI:MGI:6158728, MGI:MGI:6158784, MGI:MGI:6158885 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Rb1 RB transcriptional corepressor 1 IEA
ISO
GO_REF:0000107
(MGI:MGI:6112863|PMID:29304157)
Ensembl
RGD
PMID:29304157 GO_REF:0000107, MGI:MGI:6112863 NCBI chr15:55,081,582...55,209,060
Ensembl chr15:55,083,140...55,209,342
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO UniProtKB:Q7TPD3 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 ISO UniProtKB:O89026 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Rock1 Rho-associated coiled-coil containing protein kinase 1 ISO UniProtKB:M3TYT0 (PMID:26634652) RGD PMID:26634652 NCBI chr18:1,273,490...1,390,790
Ensembl chr18:1,273,453...1,390,190
JBrowse link
G Rock2 Rho-associated coiled-coil containing protein kinase 2 ISO UniProtKB:I3LFH3 (PMID:26634652) RGD PMID:26634652 NCBI chr 6:42,180,864...42,289,910
Ensembl chr 6:42,180,894...42,289,908
JBrowse link
G Slit2 slit guidance ligand 2 ISO (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Slit3 slit guidance ligand 3 IEA
ISO
GO_REF:0000107
(MGI:MGI:5913048|PMID:25691540)
Ensembl
RGD
PMID:25691540 GO_REF:0000107, MGI:MGI:5913048 NCBI chr10:19,924,200...20,517,918
Ensembl chr10:20,320,878...20,518,518
JBrowse link
G Smad6 SMAD family member 6 ISO (PMID:22275001) RGD PMID:22275001 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Sox9 SRY-box transcription factor 9 ISO (PMID:22110751) RGD PMID:22110751 NCBI chr10:101,288,528...101,294,030
Ensembl chr10:101,288,489...101,293,379
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (PMID:18275040), (PMID:18834961) RGD PMID:18275040, PMID:18834961 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
G Tgfb1 transforming growth factor, beta 1 ISO (PMID:26634652)
(MGI:MGI:5921830|PMID:26634652)
RGD PMID:26634652 MGI:MGI:5921830 NCBI chr 1:82,480,875...82,497,196
Ensembl chr 1:82,480,195...82,497,199
JBrowse link
G Twist1 twist family bHLH transcription factor 1 ISO (MGI:MGI:4838344|PMID:20804746)
(PMID:20804746)
RGD PMID:20804746 MGI:MGI:4838344 NCBI chr 6:53,401,241...53,403,235
Ensembl chr 6:53,401,109...53,403,214
JBrowse link
pulmonary valve development term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmpr2 bone morphogenetic protein receptor type 2 ISO GO:1905314 (MGI:MGI:2429424|PMID:12441304) RGD PMID:12441304 MGI:MGI:2429424 NCBI chr 9:66,568,074...66,683,019
Ensembl chr 9:66,568,074...66,676,494
JBrowse link
G Rbpj recombination signal binding protein for immunoglobulin kappa J region ISO (MGI:MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:MGI:6158728 NCBI chr14:59,657,738...59,865,427
Ensembl chr14:59,658,935...59,735,450
JBrowse link
G Tnfrsf1a TNF receptor superfamily member 1A ISO
IEA
UniProtKB:P25119 (MGI:MGI:6158728|PMID:26491108)
GO_REF:0000107
RGD
Ensembl
PMID:26491108 GO_REF:0000107, MGI:MGI:6158728 NCBI chr 4:157,864,905...157,877,634
Ensembl chr 4:157,864,969...157,877,633
JBrowse link
G Tnfrsf1b TNF receptor superfamily member 1B ISO UniProtKB:P25118 (MGI:MGI:6158728|PMID:26491108) RGD PMID:26491108 MGI:MGI:6158728 NCBI chr 5:163,136,390...163,167,299
Ensembl chr 5:163,136,390...163,167,299
JBrowse link
pulmonary valve formation term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Gja5 gap junction protein, alpha 5 ISO (PMID:22199024) RGD PMID:22199024 NCBI chr 2:199,162,745...199,184,942
Ensembl chr 2:199,162,745...199,184,939
JBrowse link
G Tbx20 T-box transcription factor 20 ISO (MGI:MGI:3604925|PMID:15843409) RGD PMID:15843409 MGI:MGI:3604925 NCBI chr 8:25,849,394...25,904,570
Ensembl chr 8:25,850,962...25,904,570
JBrowse link
pulmonary valve morphogenesis term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Bmp4 bone morphogenetic protein 4 IEA
ISO
GO_REF:0000107
(MGI:MGI:3039210|PMID:15070745), (MGI:MGI:3814273|PMID:18924235)
Ensembl
RGD
PMID:15070745, PMID:18924235 GO_REF:0000107, MGI:MGI:3039210, MGI:MGI:3814273 NCBI chr15:20,776,060...20,791,013
Ensembl chr15:20,776,054...20,822,740
JBrowse link
G Hey1 hes-related family bHLH transcription factor with YRPW motif 1 ISO UniProtKB:Q9DBX7 (MGI:MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:MGI:3783952 NCBI chr 2:95,320,147...95,322,701
Ensembl chr 2:95,320,283...95,322,696
JBrowse link
G Hey2 hes-related family bHLH transcription factor with YRPW motif 2 ISO (MGI:MGI:2386835|PMID:12372254) RGD PMID:12372254 MGI:MGI:2386835 NCBI chr 1:29,191,170...29,201,257
Ensembl chr 1:29,191,192...29,201,531
JBrowse link
G Heyl hes-related family bHLH transcription factor with YRPW motif-like ISO UniProtKB:Q9WV93 (MGI:MGI:3783952|PMID:17303760) RGD PMID:17303760 MGI:MGI:3783952 NCBI chr 5:140,923,914...140,940,905
Ensembl chr 5:140,923,914...140,940,905
JBrowse link
G Jag1 jagged canonical Notch ligand 1 IEA
ISO
GO_REF:0000107
(PMID:20437614), (PMID:9207787)
Ensembl
RGD
PMID:9207787, PMID:20437614 GO_REF:0000107 NCBI chr 3:130,079,361...130,114,781
Ensembl chr 3:130,079,361...130,114,770
JBrowse link
G Nfatc1 nuclear factor of activated T-cells 1 ISO MGI:MGI:2181762 (MGI:MGI:1197815|PMID:9515964) RGD PMID:9515964 MGI:MGI:1197815 NCBI chr18:77,203,517...77,322,690
Ensembl chr18:77,203,525...77,322,690
JBrowse link
G Nos3 nitric oxide synthase 3 IEA
ISO
GO_REF:0000107
UniProtKB:Q01705 (MGI:MGI:6158784|PMID:27107132)
Ensembl
RGD
PMID:27107132 GO_REF:0000107, MGI:MGI:6158784 NCBI chr 4:7,321,908...7,342,404
Ensembl chr 4:7,320,668...7,342,410
JBrowse link
G Notch1 notch receptor 1 ISO (PMID:16025100)
UniProtKB:P70313 (MGI:MGI:6158728|PMID:26491108), (MGI:MGI:6158784|PMID:27107132)
RGD PMID:16025100, PMID:26491108, PMID:27107132 MGI:MGI:6158728, MGI:MGI:6158784 NCBI chr 3:3,905,562...3,951,015
Ensembl chr 3:3,905,453...3,951,025
JBrowse link
G Notch2 notch receptor 2 ISO
IEA
(PMID:16773578)
GO_REF:0000107
RGD
Ensembl
PMID:16773578 GO_REF:0000107 NCBI chr 2:200,187,184...200,320,403
Ensembl chr 2:200,187,179...200,320,215
JBrowse link
G Robo1 roundabout guidance receptor 1 ISO UniProtKB:Q7TPD3 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:9,079,291...10,146,302
Ensembl chr11:9,642,365...10,143,317
JBrowse link
G Robo2 roundabout guidance receptor 2 ISO UniProtKB:O89026 (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr11:11,062,866...12,618,793
Ensembl chr11:11,062,790...11,585,765
JBrowse link
G Slit2 slit guidance ligand 2 ISO (MGI:MGI:5913048|PMID:25691540) RGD PMID:25691540 MGI:MGI:5913048 NCBI chr14:66,831,848...67,171,491
Ensembl chr14:66,831,848...67,170,361
JBrowse link
G Smad6 SMAD family member 6 ISO (MGI:MGI:1352979|PMID:10655064) RGD PMID:10655064 MGI:MGI:1352979 NCBI chr 8:68,897,746...68,967,221
Ensembl chr 8:68,898,296...68,966,108
JBrowse link
G Stra6 signaling receptor and transporter of retinol STRA6 ISO
IEA
(PMID:17273977)
GO_REF:0000107
RGD
Ensembl
PMID:17273977 GO_REF:0000107 NCBI chr 8:62,925,364...62,944,438
Ensembl chr 8:62,925,357...62,944,437
JBrowse link
G Tgfb2 transforming growth factor, beta 2 ISO (MGI:MGI:894212|PMID:9217007) RGD PMID:9217007 MGI:MGI:894212 NCBI chr13:105,039,639...105,142,010
Ensembl chr13:105,039,853...105,141,030
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        heart valve development 59
          semi-lunar valve development 33
            aortic valve development + 25
            pulmonary valve development + 21
Path 2
Term Annotations click to browse term
  biological_process 20017
    developmental process 6813
      anatomical structure development 6256
        multicellular organism development 5735
          system development 5272
            animal organ development 4027
              heart development 687
                heart valve development 59
                  semi-lunar valve development 33
                    aortic valve development + 25
                    pulmonary valve development + 21
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.