ONTOLOGY REPORT - ANNOTATIONS


Term:negative regulation of morphogenesis of an epithelium
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Accession:GO:1905331 term browser browse the term
Definition:Any process that stops, prevents or reduces the frequency, rate or extent of morphogenesis of an epithelium.
Comment:An example of this is MMRN2 in human (Q9H8L6) in PMID:25745997 (inferred from direct assay).
Synonyms:exact_synonym: down regulation of epithelium morphogenesis;   down regulation of morphogenesis of an epithelium;   downregulation of epithelium morphogenesis;   downregulation of morphogenesis of an epithelium;   negative regulation of epithelium morphogenesis
 narrow_synonym: inhibition of epithelium morphogenesis;   inhibition of morphogenesis of an epithelium


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negative regulation of branch elongation involved in ureteric bud branching by BMP signaling pathway term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
negative regulation of branching involved in lung morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tnf tumor necrosis factor JBrowse link 20 5,189,382 5,192,000 RGD:1624291
negative regulation of branching involved in ureteric bud morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Tacstd2 tumor-associated calcium signal transducer 2 JBrowse link 4 98,341,187 98,342,887 RGD:1600115
RGD:1624291
negative regulation of convergent extension involved in axis elongation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Nkd1 NKD inhibitor of WNT signaling pathway 1 JBrowse link 19 19,434,720 19,509,087 RGD:1624291
RGD:1600115
negative regulation of fibroblast growth factor receptor signaling pathway involved in ureteric bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
negative regulation of glial cell-derived neurotrophic factor receptor signaling pathway involved in ureteric bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Gata3 GATA binding protein 3 JBrowse link 17 72,419,752 72,452,043 RGD:1624291
RGD:1600115
negative regulation of heart looping term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Tbx2 T-box 2 JBrowse link 10 73,278,932 73,290,764 RGD:1624291
negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Cited1 Cbp/p300-interacting transactivator with Glu/Asp-rich carboxy-terminal domain 1 JBrowse link X 72,128,996 72,133,692 RGD:8554075
G Ctnnb1 catenin beta 1 JBrowse link 8 129,601,511 129,628,378 RGD:1624291
RGD:1600115
G Sall1 spalt-like transcription factor 1 JBrowse link 19 23,387,737 23,405,025 RGD:1624291
negative regulation of planar cell polarity pathway involved in neural tube closure term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of planar cell polarity pathway involved in pericardium morphogenesis term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Lrp6 LDL receptor related protein 6 JBrowse link 4 168,194,054 168,323,962 RGD:1624291
negative regulation of prostatic bud formation term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bmp4 bone morphogenetic protein 4 JBrowse link 15 20,776,060 20,791,013 RGD:1600115
RGD:1624291
G Bmp7 bone morphogenetic protein 7 JBrowse link 3 170,879,972 170,955,820 RGD:1624291
RGD:1600115
G Sulf1 sulfatase 1 JBrowse link 5 5,999,520 6,186,901 RGD:1600115
RGD:1624291
G Wnt5a Wnt family member 5A JBrowse link 16 4,469,451 4,490,271 RGD:1624291
RGD:1600115
negative regulation of wound healing, spreading of epidermal cells term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clasp1 cytoplasmic linker associated protein 1 JBrowse link 13 34,365,038 34,584,651 RGD:1624291
RGD:1600115
G Clasp2 cytoplasmic linker associated protein 2 JBrowse link 8 122,003,719 122,185,495 RGD:1624291
G Phldb2 pleckstrin homology-like domain, family B, member 2 JBrowse link 11 60,042,879 60,051,229 RGD:1624291
G Pten phosphatase and tensin homolog JBrowse link 1 251,421,814 251,487,634 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 17941
    negative regulation of biological process 5369
      negative regulation of developmental process 1077
        negative regulation of morphogenesis of an epithelium 17
          negative regulation of branching involved in lung morphogenesis + 1
          negative regulation of branching involved in ureteric bud morphogenesis + 2
          negative regulation of convergent extension involved in axis elongation + 1
          negative regulation of convergent extension involved in gastrulation + 0
          negative regulation of endothelial tube morphogenesis 0
          negative regulation of epiboly involved in gastrulation with mouth forming second 0
          negative regulation of epithelial tube formation + 2
          negative regulation of heart looping 1
          negative regulation of imaginal disc-derived leg joint morphogenesis 0
          negative regulation of imaginal disc-derived wing vein specification 0
          negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 3
          negative regulation of otic vesicle morphogenesis 0
          negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 1
          negative regulation of polarized epithelial cell differentiation 0
          negative regulation of prostatic bud formation 4
          negative regulation of vessel branching 0
          negative regulation of wound healing, spreading of epidermal cells 4
Path 2
Term Annotations click to browse term
  biological_process 17941
    developmental process 6374
      anatomical structure development 5982
        tissue development 2021
          tissue morphogenesis 688
            morphogenesis of an epithelium 557
              regulation of morphogenesis of an epithelium 113
                negative regulation of morphogenesis of an epithelium 17
                  negative regulation of branching involved in lung morphogenesis + 1
                  negative regulation of branching involved in ureteric bud morphogenesis + 2
                  negative regulation of convergent extension involved in axis elongation + 1
                  negative regulation of convergent extension involved in gastrulation + 0
                  negative regulation of endothelial tube morphogenesis 0
                  negative regulation of epiboly involved in gastrulation with mouth forming second 0
                  negative regulation of epithelial tube formation + 2
                  negative regulation of heart looping 1
                  negative regulation of imaginal disc-derived leg joint morphogenesis 0
                  negative regulation of imaginal disc-derived wing vein specification 0
                  negative regulation of mesenchymal to epithelial transition involved in metanephros morphogenesis 3
                  negative regulation of otic vesicle morphogenesis 0
                  negative regulation of planar cell polarity pathway involved in pericardium morphogenesis 1
                  negative regulation of polarized epithelial cell differentiation 0
                  negative regulation of prostatic bud formation 4
                  negative regulation of vessel branching 0
                  negative regulation of wound healing, spreading of epidermal cells 4
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.