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ONTOLOGY REPORT - ANNOTATIONS


Term:endonuclease complex
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Accession:GO:1905348 term browser browse the term
Definition:A protein complex which is capable of endonuclease activity.
Comment:An example of this is MUS81 in human (Q96NY9) in PMID:18413719 (inferred from direct assay).


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endodeoxyribonuclease complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Rag1 recombination activating 1 JBrowse link 3 91,206,394 91,217,491 RGD:13792537
Holliday junction resolvase complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Eme1 essential meiotic structure-specific endonuclease 1 JBrowse link 10 82,366,820 82,375,510 RGD:13792537
G Eme2 essential meiotic structure-specific endonuclease subunit 2 JBrowse link 10 14,253,552 14,257,017 RGD:13792537
G Mus81 MUS81 structure-specific endonuclease subunit JBrowse link 1 220,862,474 220,867,973 RGD:13792537
G Rad51c RAD51 paralog C JBrowse link 10 74,697,713 74,724,004 RGD:1624291
RGD:13792537
G Slx4 SLX4 structure-specific endonuclease subunit JBrowse link 10 11,787,756 11,808,326 RGD:1624291
Las1 complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Las1l LAS1-like, ribosome biogenesis factor JBrowse link X 65,081,591 65,102,344 RGD:1600115
microprocessor complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Dgcr8 DGCR8 microprocessor complex subunit JBrowse link 11 86,852,682 86,885,233 RGD:1624291
RGD:13792537
G Drosha drosha ribonuclease III JBrowse link 2 62,887,267 63,000,307 RGD:1624291
mitochondrial ribonuclease P complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Hsd17b10 hydroxysteroid (17-beta) dehydrogenase 10 JBrowse link X 21,696,796 21,699,241 RGD:1600115
RGD:1624291
G Prorp protein only RNase P catalytic subunit JBrowse link 6 76,079,880 76,171,298 RGD:1624291
RGD:1600115
G Trmt10c tRNA methyltransferase 10C, mitochondrial RNase P subunit JBrowse link 11 47,047,342 47,052,420 RGD:13792537
multimeric ribonuclease P complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pop1 POP1 homolog, ribonuclease P/MRP subunit JBrowse link 7 73,270,403 73,298,209 RGD:1624291
G Pop4 POP4 homolog, ribonuclease P/MRP subunit JBrowse link 1 94,661,127 94,669,461 RGD:1624291
RGD:1600115
G Pop5 POP5 homolog, ribonuclease P/MRP subunit JBrowse link 12 47,138,346 47,143,152 RGD:1624291
G Pop7 POP7 homolog, ribonuclease P/MRP subunit JBrowse link 12 22,259,713 22,260,754 RGD:1624291
G Rpp14 ribonuclease P/MRP subunit p14 JBrowse link 15 18,625,963 18,636,157 RGD:1624291
G Rpp21 ribonuclease P/MRP subunit p21 JBrowse link 20 2,515,541 2,517,471 RGD:1624291
G Rpp25 ribonuclease P and MRP subunit p25 JBrowse link 8 62,283,336 62,284,716 RGD:1624291
RGD:1600115
G Rpp30 ribonuclease P/MRP subunit p30 JBrowse link 1 254,697,247 254,720,093 RGD:1624291
G Rpp38 ribonuclease P/MRP subunit p38 JBrowse link 17 78,915,450 78,919,144 RGD:1624291
G Rpp40 ribonuclease P/MRP subunit p40 JBrowse link 17 29,638,647 29,647,709 RGD:1624291
RGD:1600115
nucleolar ribonuclease P complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pop1 POP1 homolog, ribonuclease P/MRP subunit JBrowse link 7 73,270,403 73,298,209 RGD:1624291
RGD:13792537
G Pop5 POP5 homolog, ribonuclease P/MRP subunit JBrowse link 12 47,138,346 47,143,152 RGD:1624291
RGD:13792537
G Rpp21 ribonuclease P/MRP subunit p21 JBrowse link 20 2,515,541 2,517,471 RGD:13792537
G Rpp30 ribonuclease P/MRP subunit p30 JBrowse link 1 254,697,247 254,720,093 RGD:13792537
ribonuclease P complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Pop4 POP4 homolog, ribonuclease P/MRP subunit JBrowse link 1 94,661,127 94,669,461 RGD:13792537
RISC-loading complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Ago1 argonaute RISC component 1 JBrowse link 5 144,444,390 144,479,430 RGD:1624291
G Ago2 argonaute RISC catalytic component 2 JBrowse link 7 114,339,607 114,377,277 RGD:1624291
RGD:1600115
G Ago3 argonaute RISC catalytic component 3 JBrowse link 5 144,355,792 144,436,509 RGD:1624291
G Ago4 argonaute RISC component 4 JBrowse link 5 144,501,875 144,557,165 RGD:1624291
G Dhx9 DExH-box helicase 9 JBrowse link 13 70,885,503 70,922,278 RGD:1624291
G Dicer1 dicer 1 ribonuclease III JBrowse link 6 128,388,084 128,453,234 RGD:1624291
G Mir27a microRNA 27a JBrowse link 19 25,318,736 25,318,822 RGD:1624291
G Mir28 microRNA 28 JBrowse link 11 79,380,523 79,380,608 RGD:1624291
G Prkra protein activator of interferon induced protein kinase EIF2AK2 JBrowse link 3 63,489,081 63,507,918 RGD:1600115
RGD:1624291
G Tarbp2 TARBP2 subunit of RISC loading complex JBrowse link 7 144,121,688 144,126,860 RGD:1600115
RGD:1624291
G Zfp36 zinc finger protein 36 JBrowse link 1 85,380,088 85,382,565 RGD:1624291
RGD:1600115
tRNA-intron endonuclease complex term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Clp1 cleavage factor polyribonucleotide kinase subunit 1 JBrowse link 3 72,125,269 72,137,122 RGD:1624291
RGD:1600115
G Tsen2 tRNA splicing endonuclease subunit 2 JBrowse link 4 147,455,506 147,490,869 RGD:13792537
G Tsen34 tRNA splicing endonuclease subunit 34 JBrowse link 1 64,023,924 64,031,756 RGD:1600115
G Tsen34l1 tRNA splicing endonuclease subunit 34-like 1 JBrowse link 1 64,092,224 64,100,061 RGD:1600115
G Tsen54 tRNA splicing endonuclease subunit 54 JBrowse link 10 104,358,401 104,366,926 RGD:13792537

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19843
    intracellular 13806
      endonuclease complex 38
        endodeoxyribonuclease complex + 6
        endoribonuclease complex + 32
Path 2
Term Annotations click to browse term
  cellular_component 19843
    protein-containing complex 5779
      catalytic complex 1437
        endonuclease complex 38
          endodeoxyribonuclease complex + 6
          endoribonuclease complex + 32
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.