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ONTOLOGY REPORT - ANNOTATIONS


Term:response to nerve growth factor
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Accession:GO:1990089 term browser browse the term
Definition:A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
Synonyms:exact_synonym: response to nerve growth factor stimulus


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response to nerve growth factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor ISO RGD PMID:10366647 RGD:8657096 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G KCNC1 potassium voltage-gated channel subfamily C member 1 IEA Ensembl GO_REF:0000107 NCBI chr11:17,734,781...17,783,057
Ensembl chr11:17,734,774...17,856,804
JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 IEA Ensembl GO_REF:0000107 NCBI chr12:75,040,078...75,209,839
Ensembl chr12:75,040,077...75,209,868
Ensembl chr12:75,040,077...75,209,868
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO RGD PMID:11356687 RGD:10412693 NCBI chr 5:180,233,143...180,292,083
Ensembl chr 5:180,233,143...180,292,099
JBrowse link
G PTN pleiotrophin IEA Ensembl GO_REF:0000107 NCBI chr 7:137,227,341...137,343,733
Ensembl chr 7:137,227,341...137,343,774
JBrowse link
cellular response to brain-derived neurotrophic factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRNKL1 crooked neck pre-mRNA splicing factor 1 ISO RGD PMID:12801913 RGD:634609 NCBI chr20:20,034,368...20,056,046
Ensembl chr20:20,034,368...20,056,046
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 IEA Ensembl GO_REF:0000107 NCBI chr19:3,976,056...3,985,463
Ensembl chr19:3,976,056...3,985,463
JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase IEA Ensembl GO_REF:0000107 NCBI chr16:22,206,278...22,288,738
Ensembl chr16:22,206,278...22,288,738
JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 IEA Ensembl GO_REF:0000107 NCBI chr17:80,134,369...80,147,128
Ensembl chr17:80,134,369...80,147,151
JBrowse link
G IRS1 insulin receptor substrate 1 ISO RGD PMID:17467122 RGD:10045898 NCBI chr 2:226,731,312...226,799,820
Ensembl chr 2:226,731,317...226,799,759
JBrowse link
G MAPT microtubule associated protein tau TAS (PMID:28386764) ARUK-UCL PMID:28386764 NCBI chr17:45,894,538...46,028,334
Ensembl chr17:45,894,551...46,028,334
Ensembl chr17:45,894,551...46,028,334
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 ISO RGD PMID:11520908 RGD:10045822 NCBI chr 4:102,501,266...102,617,302
Ensembl chr 4:102,501,331...102,617,302
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:84,668,458...85,027,070
Ensembl chr 9:84,668,551...85,027,070
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 IEA Ensembl GO_REF:0000107 NCBI chr16:2,538,014...2,603,190
Ensembl chr16:2,537,979...2,603,188
JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 ISS UniProtKB GO_REF:0000024 NCBI chr 9:17,579,066...17,797,124
Ensembl chr 9:17,579,066...17,797,124
JBrowse link
G TMEM108 transmembrane protein 108 ISS UniProtKB GO_REF:0000024 NCBI chr 3:133,038,391...133,397,775
Ensembl chr 3:133,038,391...133,397,792
JBrowse link
G UBE3A ubiquitin protein ligase E3A IEA Ensembl GO_REF:0000107 NCBI chr15:25,333,728...25,439,381
Ensembl chr15:25,333,728...25,439,051
JBrowse link
G WASF1 WASP family member 1 ISS UniProtKB GO_REF:0000024 NCBI chr 6:110,099,819...110,179,670
Ensembl chr 6:110,099,819...110,180,004
JBrowse link
cellular response to nerve growth factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 ISS UniProtKB GO_REF:0000024 NCBI chr 3:195,274,742...195,443,176
Ensembl chr 3:195,274,745...195,443,044
JBrowse link
G AKT1 AKT serine/threonine kinase 1 IMP (PMID:20605787) UniProtKB PMID:20605787 NCBI chr14:104,769,349...104,795,748
Ensembl chr14:104,769,349...104,795,751
JBrowse link
G APC APC regulator of WNT signaling pathway ISO RGD PMID:22399805 RGD:7245986 NCBI chr 5:112,707,498...112,846,239
Ensembl chr 5:112,707,498...112,846,239
JBrowse link
G APP amyloid beta precursor protein IEA Ensembl GO_REF:0000107 NCBI chr21:25,880,550...26,171,128
Ensembl chr21:25,880,550...26,171,128
JBrowse link
G ARF6 ADP ribosylation factor 6 IEA Ensembl GO_REF:0000107 NCBI chr14:49,893,082...49,897,054
Ensembl chr14:49,893,082...49,897,054
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:10797548 RGD:11049163 NCBI chr 2:218,217,138...218,254,348
Ensembl chr 2:218,217,141...218,254,356
JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 IEA Ensembl GO_REF:0000107 NCBI chr12:110,434,823...110,450,337
Ensembl chr12:110,434,823...110,450,422
JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:21958434 RGD:8657122 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G BPTF bromodomain PHD finger transcription factor ISO RGD PMID:11640947 RGD:9586055 NCBI chr17:67,825,503...67,984,378
Ensembl chr17:67,825,503...67,984,378
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase IEA Ensembl GO_REF:0000107 NCBI chr 7:140,713,328...140,924,929
Ensembl chr 7:140,719,327...140,924,929
Ensembl chr 7:140,719,327...140,924,929
JBrowse link
G CALCA calcitonin related polypeptide alpha IEA Ensembl GO_REF:0000107 NCBI chr11:14,966,668...14,972,361
Ensembl chr11:14,966,668...14,972,354
JBrowse link
G CBL Cbl proto-oncogene IEA Ensembl GO_REF:0000107 NCBI chr11:119,206,339...119,308,149
Ensembl chr11:119,206,298...119,313,926
Ensembl chr11:119,206,298...119,313,926
JBrowse link
G CDC5L cell division cycle 5 like IEA Ensembl GO_REF:0000107 NCBI chr 6:44,387,706...44,450,425
Ensembl chr 6:44,387,706...44,450,425
JBrowse link
G CIB1 calcium and integrin binding 1 IDA (PMID:21215777) UniProtKB PMID:21215777 NCBI chr15:90,229,975...90,265,759
Ensembl chr15:90,229,975...90,234,047
JBrowse link
G CREB1 cAMP responsive element binding protein 1 IEA Ensembl GO_REF:0000107 NCBI chr 2:207,529,943...207,605,988
Ensembl chr 2:207,529,737...207,605,988
JBrowse link
G CRK CRK proto-oncogene, adaptor protein IEA Ensembl GO_REF:0000107 NCBI chr17:1,420,693...1,456,232
Ensembl chr17:1,420,689...1,463,162
JBrowse link
G CSNK1D casein kinase 1 delta IEA Ensembl GO_REF:0000107 NCBI chr17:82,239,019...82,273,750
Ensembl chr17:82,239,023...82,273,731
JBrowse link
G CSNK1E casein kinase 1 epsilon ISO RGD PMID:21698236 RGD:10059659 NCBI chr22:38,290,691...38,318,084
Ensembl chr22:38,290,691...38,318,084
JBrowse link
G CSTF2 cleavage stimulation factor subunit 2 IEA Ensembl GO_REF:0000107 NCBI chr  X:100,820,369...100,843,534
Ensembl chr  X:100,820,359...100,841,520
Ensembl chr  X:100,820,359...100,841,520
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:10407183 RGD:9588607 NCBI chr19:10,133,346...10,194,953
Ensembl chr19:10,133,345...10,231,286
JBrowse link
G DYNC1H1 dynein cytoplasmic 1 heavy chain 1 ISO RGD PMID:8922673 RGD:13207348 NCBI chr14:101,964,573...102,056,443
Ensembl chr14:101,964,573...102,056,443
JBrowse link
G DYNC1I2 dynein cytoplasmic 1 intermediate chain 2 ISO RGD PMID:11536324 RGD:13207410 NCBI chr 2:171,687,469...171,750,158
Ensembl chr 2:171,687,409...171,750,158
Ensembl chr 2:171,687,409...171,750,158
JBrowse link
G DYNC1LI1 dynein cytoplasmic 1 light intermediate chain 1 ISO RGD PMID:11536324 RGD:13207410 NCBI chr 3:32,525,974...32,570,858
Ensembl chr 3:32,525,974...32,570,858
JBrowse link
G DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 IEA Ensembl GO_REF:0000107 NCBI chr16:66,720,893...66,751,609
Ensembl chr16:66,720,893...66,751,609
JBrowse link
G E2F1 E2F transcription factor 1 IEA Ensembl GO_REF:0000107 NCBI chr20:33,675,477...33,686,385
Ensembl chr20:33,675,477...33,686,385
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:11907030 RGD:1304240 NCBI chr 6:73,515,750...73,521,032
Ensembl chr 6:73,515,750...73,523,797
JBrowse link
G EHD1 EH domain containing 1 IEA
ISS
Ensembl
UniProtKB
GO_REF:0000024, GO_REF:0000107 NCBI chr11:64,851,642...64,879,693
Ensembl chr11:64,851,642...64,888,296
JBrowse link
G ELAVL4 ELAV like RNA binding protein 4 IEA Ensembl GO_REF:0000107 NCBI chr 1:50,048,055...50,203,772
Ensembl chr 1:50,024,029...50,203,786
Ensembl chr 1:50,024,029...50,203,786
JBrowse link
G EP300 E1A binding protein p300 ISO RGD PMID:20399742 RGD:7364749 NCBI chr22:41,092,592...41,180,077
Ensembl chr22:41,092,592...41,180,077
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:9011767 RGD:10402043 NCBI chr 8:38,411,143...38,468,635
Ensembl chr 8:38,400,215...38,468,834
JBrowse link
G FOXO3 forkhead box O3 IEA Ensembl GO_REF:0000107 NCBI chr 6:108,559,825...108,684,774
Ensembl chr 6:108,559,835...108,684,774
JBrowse link
G HES1 hes family bHLH transcription factor 1 ISO RGD PMID:9389649 RGD:9685378 NCBI chr 3:194,136,148...194,138,732
Ensembl chr 3:194,136,148...194,138,732
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 IEA Ensembl GO_REF:0000107 NCBI chr 9:125,234,853...125,241,343
Ensembl chr 9:125,234,853...125,241,343
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein IEA Ensembl GO_REF:0000107 NCBI chr20:31,605,289...31,606,510
Ensembl chr20:31,605,283...31,606,515
JBrowse link
G KAT2A lysine acetyltransferase 2A IEA Ensembl GO_REF:0000107 NCBI chr17:42,113,111...42,121,367
Ensembl chr17:42,113,111...42,121,367
JBrowse link
G KIDINS220 kinase D interacting substrate 220 ISS UniProtKB GO_REF:0000024 NCBI chr 2:8,721,081...8,837,613
Ensembl chr 2:8,721,081...8,837,630
JBrowse link
G KIF1B kinesin family member 1B IEA Ensembl GO_REF:0000107 NCBI chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603
Ensembl chr 1:10,210,570...10,381,603
JBrowse link
G KIF5A kinesin family member 5A ISO RGD PMID:8963445 RGD:12793074 NCBI chr12:57,550,039...57,586,633
Ensembl chr12:57,546,026...57,586,633
Ensembl chr12:57,546,026...57,586,633
JBrowse link
G L1CAM L1 cell adhesion molecule ISO RGD PMID:3511068 RGD:11570521 NCBI chr  X:153,861,514...153,886,173
Ensembl chr  X:153,861,514...153,886,173
JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISS UniProtKB GO_REF:0000024 NCBI chr 7:78,017,055...79,453,667
Ensembl chr 7:78,017,055...79,453,667
JBrowse link
G MAPT microtubule associated protein tau TAS (PMID:28386764) ARUK-UCL PMID:28386764 NCBI chr17:45,894,538...46,028,334
Ensembl chr17:45,894,551...46,028,334
Ensembl chr17:45,894,551...46,028,334
JBrowse link
G MICALL1 MICAL like 1 IEA Ensembl GO_REF:0000107 NCBI chr22:37,906,176...37,942,822
Ensembl chr22:37,905,657...37,942,822
JBrowse link
G MYOC myocilin ISO RGD PMID:17663725 RGD:7401258 NCBI chr 1:171,635,417...171,652,688
Ensembl chr 1:171,635,417...171,652,688
JBrowse link
G NF1 neurofibromin 1 ISO RGD PMID:8892969 RGD:12789704 NCBI chr17:31,094,927...31,377,677
Ensembl chr17:31,094,927...31,382,116
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IMP
IBA
ISS
(PMID:1281417)
(PMID:21873635)
UniProtKB
GO_Central
PMID:1281417, PMID:21873635 GO_REF:0000024 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,640...156,881,850
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 9:84,668,458...85,027,070
Ensembl chr 9:84,668,551...85,027,070
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr15:87,859,749...88,256,796
Ensembl chr15:87,859,751...88,256,768
JBrowse link
G NTS neurotensin ISO RGD PMID:7898306 RGD:9743905 NCBI chr12:85,874,295...85,882,992
Ensembl chr12:85,874,295...85,882,992
JBrowse link
G OPTN optineurin ISO RGD PMID:17663725 RGD:7401258 NCBI chr10:13,100,082...13,138,308
Ensembl chr10:13,099,449...13,138,308
JBrowse link
G PTEN phosphatase and tensin homolog IEA Ensembl GO_REF:0000107 NCBI chr10:87,863,625...87,971,930
Ensembl chr10:87,863,625...87,971,930
JBrowse link
G RAB35 RAB35, member RAS oncogene family ISS UniProtKB GO_REF:0000024 NCBI chr12:120,095,094...120,117,469
Ensembl chr12:120,095,099...120,117,502
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISS UniProtKB GO_REF:0000024 NCBI chr 1:111,542,009...111,716,695
Ensembl chr 1:111,542,218...111,716,691
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 IDA (PMID:17724123) UniProtKB PMID:17724123 NCBI chr 9:131,576,770...131,740,076
Ensembl chr 9:131,576,770...131,740,074
JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 ISS UniProtKB GO_REF:0000024 NCBI chr 4:159,104,051...159,360,169
Ensembl chr 4:159,103,013...159,360,174
JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 ISO RGD PMID:25126967 RGD:9850100 NCBI chr 2:172,735,282...173,052,893
Ensembl chr 2:172,735,274...173,052,893
JBrowse link
G RPL8 ribosomal protein L8 ISO RGD PMID:11922865 RGD:11039448 NCBI chr 8:144,789,769...144,792,390
Ensembl chr 8:144,789,765...144,792,587
JBrowse link
G RPL9 ribosomal protein L9 ISO RGD PMID:11922865 RGD:11039448 NCBI chr 4:39,454,124...39,458,922
Ensembl chr 4:39,452,587...39,458,931
Ensembl chr 4:39,452,587...39,458,931
JBrowse link
G RPS3 ribosomal protein S3 ISO PMID:20605787 UniProt PMID:20605787 RGD:10402036 NCBI chr11:75,399,518...75,422,302
Ensembl chr11:75,399,515...75,422,280
JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:21596853 RGD:8547918 NCBI chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
Ensembl chr 7:101,127,104...101,139,247
JBrowse link
G SNX27 sorting nexin 27 ISO RGD PMID:16076023 RGD:13508621 NCBI chr 1:151,612,027...151,699,080
Ensembl chr 1:151,612,006...151,699,091
JBrowse link
G STMN2 stathmin 2 IDA (PMID:21215777) UniProtKB PMID:21215777 NCBI chr 8:79,611,117...79,666,162
Ensembl chr 8:79,610,814...79,666,175
Ensembl chr 8:79,610,814...79,666,175
JBrowse link
G TAC1 tachykinin precursor 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:97,732,086...97,740,472
Ensembl chr 7:97,732,084...97,740,472
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 IEA Ensembl GO_REF:0000107 NCBI chr17:3,565,446...3,609,411
Ensembl chr17:3,565,444...3,609,411
JBrowse link
G USP8 ubiquitin specific peptidase 8 IEA Ensembl GO_REF:0000107 NCBI chr15:50,424,359...50,514,421
Ensembl chr15:50,424,380...50,514,421
JBrowse link
nerve growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr11:27,654,893...27,722,030
Ensembl chr11:27,654,893...27,722,058
JBrowse link
G CORO1A coronin 1A IEA Ensembl GO_REF:0000107 NCBI chr16:30,183,602...30,189,076
Ensembl chr16:30,182,827...30,189,076
JBrowse link
G KIDINS220 kinase D interacting substrate 220 ISS
IBA
(PMID:21873635) UniProtKB
GO_Central
PMID:21873635 GO_REF:0000024 NCBI chr 2:8,721,081...8,837,613
Ensembl chr 2:8,721,081...8,837,630
JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISS UniProtKB GO_REF:0000024 NCBI chr 7:78,017,055...79,453,667
Ensembl chr 7:78,017,055...79,453,667
JBrowse link
G NGF nerve growth factor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:115,285,915...115,338,253
Ensembl chr 1:115,285,917...115,338,256
Ensembl chr 1:115,285,917...115,338,256
Ensembl chr 1:115,285,917...115,338,256
JBrowse link
G NTF3 neurotrophin 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr12:5,432,108...5,495,299
Ensembl chr12:5,432,108...5,521,536
JBrowse link
G NTF4 neurotrophin 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr19:49,058,284...49,065,076
Ensembl chr19:49,061,066...49,065,054
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IMP
IBA
(PMID:1281417)
(PMID:21873635)
UniProtKB
GO_Central
PMID:1281417, PMID:21873635 NCBI chr 1:156,815,750...156,881,850
Ensembl chr 1:156,815,640...156,881,850
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISS UniProtKB GO_REF:0000024 NCBI chr 1:111,542,009...111,716,695
Ensembl chr 1:111,542,218...111,716,691
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 IDA (PMID:17724123) UniProtKB PMID:17724123 NCBI chr 9:131,576,770...131,740,076
Ensembl chr 9:131,576,770...131,740,074
JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 ISS UniProtKB GO_REF:0000024 NCBI chr 4:159,104,051...159,360,169
Ensembl chr 4:159,103,013...159,360,174
JBrowse link
G SORT1 sortilin 1 IEA GOC GO_REF:0000108 NCBI chr 1:109,309,575...109,397,940
Ensembl chr 1:109,309,568...109,397,918
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18626
    response to stimulus 10122
      response to endogenous stimulus 2161
        response to nerve growth factor 84
          cellular response to nerve growth factor stimulus + 80
Path 2
Term Annotations click to browse term
  biological_process 18626
    response to stimulus 10122
      response to chemical 5615
        response to organic substance 4176
          response to growth factor 867
            response to nerve growth factor 84
              cellular response to nerve growth factor stimulus + 80
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.