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ONTOLOGY REPORT - ANNOTATIONS


Term:response to nerve growth factor
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Accession:GO:1990089 term browser browse the term
Definition:A process that results in a change in state or activity of a cell or an organism (in terms of movement, secretion, enzyme production, gene expression, etc.) as a result of a nerve growth factor stimulus.
Synonyms:exact_synonym: response to nerve growth factor stimulus


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response to nerve growth factor term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor ISO RGD PMID:10366647 RGD:8657096 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,623,268...32,679,164
JBrowse link
G KCNC1 potassium voltage-gated channel subfamily C member 1 ISO brain-derived neurotrophic factor, neurotrophin 4
brain-derived neurotrophic factor, neurotrophin-3
RGD PMID:9526005, PMID:18775767 RGD:9685724, RGD:9685735 NCBI chr 2:41,362,208...41,407,935
Ensembl chr 2:41,362,347...41,408,127
JBrowse link
G KCNC2 potassium voltage-gated channel subfamily C member 2 ISO neurotrophin 4 RGD PMID:18775767 RGD:9685735 NCBI chr 5:38,326,408...38,535,826
Ensembl chr 5:38,326,408...38,533,110
JBrowse link
G MAPK9 mitogen-activated protein kinase 9 ISO RGD PMID:11356687 RGD:10412693 NCBI chr 2:78,338,466...78,399,108
Ensembl chr 2:78,338,369...78,399,105
JBrowse link
G PTN pleiotrophin ISO ciliary neurotrophic factor RGD PMID:16914133 RGD:9831439 NCBI chr18:12,219,708...12,309,045
Ensembl chr18:12,219,790...12,311,922
JBrowse link
cellular response to brain-derived neurotrophic factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G CRNKL1 crooked neck pre-mRNA splicing factor 1 ISO RGD PMID:12801913 RGD:634609 NCBI chr17:28,079,541...28,111,871
Ensembl chr17:28,077,707...28,111,545
JBrowse link
G EEF2 eukaryotic translation elongation factor 2 ISO RGD PMID:19625250 RGD:10401254 NCBI chr 2:74,746,541...74,756,687
Ensembl chr 2:74,747,080...74,756,680
JBrowse link
G EEF2K eukaryotic elongation factor 2 kinase ISO RGD PMID:19625250 RGD:10401254 NCBI chr 3:23,887,120...23,980,231
Ensembl chr 3:23,887,125...23,956,373
JBrowse link
G EIF4A3 eukaryotic translation initiation factor 4A3 ISO RGD PMID:17632064 RGD:10044262 NCBI chr12:2,285,679...2,311,750
Ensembl chr12:2,285,225...2,311,750
JBrowse link
G IRS1 insulin receptor substrate 1 ISO RGD PMID:17467122 RGD:10045898 NCBI chr15:128,245,846...128,307,321
Ensembl chr15:128,245,846...128,308,335
JBrowse link
G NFKB1 nuclear factor kappa B subunit 1 ISO RGD PMID:11520908 RGD:10045822 NCBI chr 8:118,391,010...118,478,927
Ensembl chr 8:118,390,637...118,506,691
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,379...30,429,882
JBrowse link
G PDPK1 3-phosphoinositide dependent protein kinase 1 ISO RGD PMID:18971483 RGD:10449508 NCBI chr 3:39,429,928...39,512,623
Ensembl chr 3:39,429,931...39,532,583
JBrowse link
G SH3GL2 SH3 domain containing GRB2 like 2, endophilin A1 IEA Ensembl GO_REF:0000107 NCBI chr 1:205,081,227...205,285,359
Ensembl chr 1:205,081,227...205,285,343
JBrowse link
G TMEM108 transmembrane protein 108 IEA Ensembl GO_REF:0000107 NCBI chr13:74,524,122...74,556,327
Ensembl chr13:74,180,197...74,555,946
JBrowse link
G UBE3A ubiquitin protein ligase E3A ISO RGD PMID:25867122 RGD:11079590 NCBI chr 1:141,887,179...142,001,595
Ensembl chr 1:141,887,168...141,997,241
JBrowse link
G WASF1 WASP family member 1 ISO (MGI:MGI:5825407|PMID:27605705) UniProtKB PMID:27605705 MGI:MGI:5825407 NCBI chr 1:76,107,595...76,180,335 JBrowse link
cellular response to nerve growth factor stimulus term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ACAP2 ArfGAP with coiled-coil, ankyrin repeat and PH domains 2 ISO PMID:23572513 UniProt PMID:23572513 RGD:8554201 NCBI chr13:132,274,229...132,431,442
Ensembl chr13:132,273,874...132,431,442
JBrowse link
G AKT1 AKT serine/threonine kinase 1 ISO (PMID:20605787) UniProtKB
UniProt
PMID:20605787 RGD:10402036
G APC APC regulator of WNT signaling pathway ISO RGD PMID:22399805 RGD:7245986 NCBI chr 2:116,913,354...116,985,303
Ensembl chr 2:116,812,582...117,034,912
JBrowse link
G APP amyloid beta precursor protein ISO RGD PMID:10821917 RGD:10054256 NCBI chr13:189,434,854...189,716,120
Ensembl chr13:189,434,869...189,716,057
JBrowse link
G ARF6 ADP ribosylation factor 6 ISO PMID:26446845 UniProt PMID:26446845 RGD:11554955 NCBI chr 1:179,697,582...179,717,299
Ensembl chr 1:179,697,615...179,717,844
JBrowse link
G ARPC2 actin related protein 2/3 complex subunit 2 ISO RGD PMID:10797548 RGD:11049163 NCBI chr15:120,297,122...120,328,795
Ensembl chr15:120,297,127...120,329,059
JBrowse link
G ARPC3 actin related protein 2/3 complex subunit 3 ISO RGD PMID:10797548 RGD:11049163 NCBI chr14:31,814,382...31,823,452
Ensembl chr14:31,814,150...31,826,855
JBrowse link
G BDNF brain derived neurotrophic factor ISO RGD PMID:21958434 RGD:8657122 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,623,268...32,679,164
JBrowse link
G BPTF bromodomain PHD finger transcription factor ISO RGD PMID:11640947 RGD:9586055 NCBI chr12:14,112,943...14,254,810
Ensembl chr12:14,112,643...14,255,408
JBrowse link
G BRAF B-Raf proto-oncogene, serine/threonine kinase ISO RGD PMID:12138204 RGD:11567269 NCBI chr18:8,957,963...9,132,558
Ensembl chr18:8,957,959...9,132,553
JBrowse link
G CALCB calcitonin-related polypeptide beta ISO (MGI:MGI:5571523|PMID:24760869) MGI
RGD
PMID:21958434, PMID:24760869 MGI:MGI:5571523, RGD:8657122 NCBI chr 2:44,043,135...44,048,651 JBrowse link
G CBL Cbl proto-oncogene ISO RGD PMID:19546888 RGD:11038823 NCBI chr 9:46,416,937...46,512,855
Ensembl chr 9:46,404,999...46,512,834
JBrowse link
G CDC5L cell division cycle 5 like ISO RGD PMID:20629186 RGD:10045890 NCBI chr 7:39,384,397...39,427,729
Ensembl chr 7:39,384,556...39,431,248
JBrowse link
G CIB1 calcium and integrin binding 1 IEA Ensembl GO_REF:0000107 NCBI chr 7:55,794,834...55,798,666
Ensembl chr 7:55,794,834...55,798,590
JBrowse link
G CREB1 cAMP responsive element binding protein 1 ISO RGD PMID:18193038 RGD:10059421 NCBI chr15:110,705,548...110,773,037
Ensembl chr15:110,697,408...110,771,755
JBrowse link
G CRK CRK proto-oncogene, adaptor protein ISO RGD PMID:15128873 RGD:1642627 NCBI chr12:47,656,805...47,685,641 JBrowse link
G CSNK1D casein kinase 1 delta ISO RGD PMID:21698236 RGD:10059659 NCBI chr12:768,856...794,495
Ensembl chr12:768,865...796,532
JBrowse link
G CSTF2 cleavage stimulation factor subunit 2 ISO RGD PMID:23948079 RGD:9686373 NCBI chr  X:82,508,739...82,540,861
Ensembl chr  X:82,508,736...82,540,870
JBrowse link
G DNMT1 DNA methyltransferase 1 ISO RGD PMID:10407183 RGD:9588607 NCBI chr 2:68,981,564...69,040,364
Ensembl chr 2:68,981,564...69,029,919
JBrowse link
G DYNC1H1 dynein cytoplasmic 1 heavy chain 1 ISO RGD PMID:8922673 RGD:13207348
G DYNC1I2 dynein cytoplasmic 1 intermediate chain 2 ISO RGD PMID:11536324 RGD:13207410 NCBI chr15:77,803,601...77,859,559
Ensembl chr15:77,803,349...77,859,622
JBrowse link
G DYNC1LI1 dynein cytoplasmic 1 light intermediate chain 1 ISO RGD PMID:11536324 RGD:13207410 NCBI chr13:18,507,710...18,558,057
Ensembl chr13:18,506,194...18,558,007
JBrowse link
G DYNC1LI2 dynein cytoplasmic 1 light intermediate chain 2 ISO RGD PMID:11536324 RGD:13207410 NCBI chr 6:27,416,475...27,446,172
Ensembl chr 6:27,416,477...27,446,360
JBrowse link
G E2F1 E2F transcription factor 1 ISO RGD PMID:18367454 RGD:8693614 NCBI chr17:37,178,587...37,190,118
Ensembl chr17:37,178,598...37,189,841
JBrowse link
G EEF1A1 eukaryotic translation elongation factor 1 alpha 1 ISO RGD PMID:11907030 RGD:1304240 NCBI chr 1:92,421,235...92,425,053
Ensembl chr 1:92,421,005...92,488,565
JBrowse link
G EHD1 EH domain containing 1 ISO PMID:23572513 UniProt PMID:23572513 RGD:8554201 NCBI chr 2:7,299,295...7,321,580
Ensembl chr 2:7,298,259...7,321,577
JBrowse link
G ELAVL4 ELAV like RNA binding protein 4 ISO RGD PMID:9514914, PMID:12859688 RGD:1579855, RGD:9685344 NCBI chr 6:161,784,146...161,928,953
Ensembl chr 6:161,786,352...161,928,910
JBrowse link
G EP300 E1A binding protein p300 ISO RGD PMID:20399742 RGD:7364749 NCBI chr 5:7,311,165...7,394,515
Ensembl chr 5:7,311,171...7,393,760
JBrowse link
G FGFR1 fibroblast growth factor receptor 1 ISO RGD PMID:9011767 RGD:10402043 NCBI chr15:48,053,895...48,106,634
Ensembl chr15:48,053,340...48,106,746
JBrowse link
G FOXO3 forkhead box O3 ISO RGD PMID:24183892 RGD:9495918 NCBI chr 1:74,626,673...74,760,323
Ensembl chr 1:74,628,217...74,760,328
JBrowse link
G HES1 hes family bHLH transcription factor 1 ISO RGD PMID:9389649 RGD:9685378 NCBI chr13:131,135,970...131,137,865
Ensembl chr13:131,135,724...131,138,236
JBrowse link
G HSPA5 heat shock protein family A (Hsp70) member 5 ISO RGD PMID:10936191 RGD:11354963 NCBI chr 1:265,930,044...265,934,959
Ensembl chr 1:265,930,045...265,934,904
JBrowse link
G ID1 inhibitor of DNA binding 1, HLH protein ISO RGD PMID:7623812 RGD:9686118 NCBI chr17:35,316,518...35,317,742
Ensembl chr17:35,315,964...35,317,744
JBrowse link
G KAT2A lysine acetyltransferase 2A ISO RGD PMID:15496412 RGD:2312271 NCBI chr12:20,638,493...20,647,464
Ensembl chr12:20,638,493...20,647,463
JBrowse link
G KIDINS220 kinase D interacting substrate 220 ISO PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 3:127,382,587...127,477,753
Ensembl chr 3:127,382,603...127,474,276
JBrowse link
G KIF1B kinesin family member 1B ISO RGD PMID:24469107 RGD:12738402 NCBI chr 6:70,495,143...70,663,464
Ensembl chr 6:70,495,144...70,663,463
JBrowse link
G KIF5A kinesin family member 5A ISO RGD PMID:8963445 RGD:12793074 NCBI chr 5:22,813,617...22,851,976
Ensembl chr 5:22,816,506...22,867,029
JBrowse link
G L1CAM L1 cell adhesion molecule ISO RGD PMID:3511068 RGD:11570521 NCBI chr  X:124,595,649...124,618,292
Ensembl chr  X:124,595,651...124,618,307
JBrowse link
G LOC100523244 casein kinase I ISO RGD PMID:21698236 RGD:10059659 NCBI chr 5:9,594,461...9,620,483 JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISO PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 9:100,846,693...102,171,199
Ensembl chr 9:100,847,212...102,169,003
JBrowse link
G MICALL1 MICAL like 1 ISO PMID:23572513 UniProt PMID:23572513 RGD:8554201 NCBI chr 5:9,924,648...9,956,998
Ensembl chr 5:9,924,651...9,956,947
JBrowse link
G MYOC myocilin ISO RGD PMID:17663725 RGD:7401258 NCBI chr 9:114,087,370...114,098,765
Ensembl chr 9:114,087,374...114,098,743
JBrowse link
G NF1 neurofibromin 1 ISO RGD PMID:8892969 RGD:12789704 NCBI chr12:43,487,098...43,754,205
Ensembl chr12:43,489,171...43,754,176
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:93,219,509...93,237,944
Ensembl chr 4:93,219,516...93,237,930
JBrowse link
G NTRK2 neurotrophic receptor tyrosine kinase 2 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr10:30,030,050...30,429,938
Ensembl chr10:30,033,379...30,429,882
JBrowse link
G NTRK3 neurotrophic receptor tyrosine kinase 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 1:191,535,262...191,941,675
Ensembl chr 1:191,535,300...191,925,353
JBrowse link
G NTS neurotensin ISO RGD PMID:7898306 RGD:9743905 NCBI chr 5:96,261,299...96,272,947
Ensembl chr 5:96,261,375...96,272,824
JBrowse link
G OPTN optineurin ISO RGD PMID:17663725 RGD:7401258 NCBI chr10:48,532,029...48,582,952
Ensembl chr10:48,530,844...48,582,910
JBrowse link
G PTEN phosphatase and tensin homolog ISO RGD PMID:10662831 RGD:12801496 NCBI chr14:99,929,590...100,021,619 JBrowse link
G RAB35 RAB35, member RAS oncogene family ISO PMID:23572513 UniProt PMID:23572513 RGD:8554201 NCBI chr14:40,124,318...40,141,261
Ensembl chr14:40,124,322...40,141,668
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO PMID:17724123 UniProt
RGD
PMID:17724123, PMID:17822405 RGD:10040965, RGD:8554481 NCBI chr 4:108,675,537...108,750,952
Ensembl chr 4:108,676,685...108,749,725
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 ISO (PMID:17724123) UniProtKB PMID:17724123 NCBI chr 1:271,494,243...271,624,609
Ensembl chr 1:271,494,248...271,600,879
JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 ISO PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 8:48,183,518...48,277,476
Ensembl chr 8:48,020,697...48,277,476
JBrowse link
G RAPGEF4 Rap guanine nucleotide exchange factor 4 ISO RGD PMID:25126967 RGD:9850100 NCBI chr15:78,773,270...79,094,490
Ensembl chr15:78,773,285...79,095,041
JBrowse link
G RPL8 ribosomal protein L8 ISO RGD PMID:11922865 RGD:11039448 NCBI chr 4:136,105...138,651 JBrowse link
G RPL9 ribosomal protein L9 ISO RGD PMID:11922865 RGD:11039448 NCBI chr 8:30,693,198...30,699,189 JBrowse link
G RPS3 ribosomal protein S3 ISO PMID:20605787 UniProt PMID:20605787 RGD:10402036 NCBI chr 9:9,612,939...9,630,404
Ensembl chr 9:9,616,456...9,630,413
JBrowse link
G SERPINE1 serpin family E member 1 ISO RGD PMID:21596853 RGD:8547918 NCBI chr 3:8,863,738...8,871,572
Ensembl chr 3:8,863,695...8,871,564
JBrowse link
G SNX27 sorting nexin 27 ISO RGD PMID:16076023 RGD:13508621 NCBI chr 4:97,533,643...97,620,816
Ensembl chr 4:97,525,151...97,620,789
JBrowse link
G STMN2 stathmin 2 IEA Ensembl GO_REF:0000107 NCBI chr 4:56,952,968...57,006,744
Ensembl chr 4:56,952,973...57,006,463
JBrowse link
G TAC1 tachykinin precursor 1 IEA Ensembl GO_REF:0000107 NCBI chr 9:77,197,403...77,206,529
Ensembl chr 9:77,197,535...77,206,526
JBrowse link
G TRPV1 transient receptor potential cation channel subfamily V member 1 ISO RGD PMID:21958434 RGD:8657122 NCBI chr12:49,676,536...49,709,634
Ensembl chr12:49,677,291...49,701,325
JBrowse link
G USP8 ubiquitin specific peptidase 8 ISO RGD PMID:25662281 RGD:11053004 NCBI chr 1:121,306,031...121,376,154
Ensembl chr 1:121,306,030...121,376,099
JBrowse link
nerve growth factor signaling pathway term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDNF brain derived neurotrophic factor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 2:32,623,668...32,679,293
Ensembl chr 2:32,623,268...32,679,164
JBrowse link
G CORO1A coronin 1A IEA Ensembl GO_REF:0000107 NCBI chr 3:18,336,813...18,342,381
Ensembl chr 3:18,336,899...18,342,380
JBrowse link
G KIDINS220 kinase D interacting substrate 220 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 3:127,382,587...127,477,753
Ensembl chr 3:127,382,603...127,474,276
JBrowse link
G MAGI2 membrane associated guanylate kinase, WW and PDZ domain containing 2 ISO PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 9:100,846,693...102,171,199
Ensembl chr 9:100,847,212...102,169,003
JBrowse link
G NGF nerve growth factor IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:105,256,691...105,307,843
Ensembl chr 4:105,256,417...105,307,842
JBrowse link
G NTF3 neurotrophin 3 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 5:65,052,608...65,122,645
Ensembl chr 5:65,052,517...65,123,788
JBrowse link
G NTF4 neurotrophin 4 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 6:54,271,244...54,288,846
Ensembl chr 6:54,270,553...54,288,843
JBrowse link
G NTRK1 neurotrophic receptor tyrosine kinase 1 IBA (PMID:21873635) GO_Central PMID:21873635 NCBI chr 4:93,219,509...93,237,944
Ensembl chr 4:93,219,516...93,237,930
JBrowse link
G RAP1A RAP1A, member of RAS oncogene family ISO PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 4:108,675,537...108,750,952
Ensembl chr 4:108,676,685...108,749,725
JBrowse link
G RAPGEF1 Rap guanine nucleotide exchange factor 1 IEA Ensembl GO_REF:0000107 NCBI chr 1:271,494,243...271,624,609
Ensembl chr 1:271,494,248...271,600,879
JBrowse link
G RAPGEF2 Rap guanine nucleotide exchange factor 2 ISO PMID:17724123 UniProt PMID:17724123 RGD:8554481 NCBI chr 8:48,183,518...48,277,476
Ensembl chr 8:48,020,697...48,277,476
JBrowse link
G SORT1 sortilin 1 IEA GOC GO_REF:0000108 NCBI chr 4:110,721,110...110,791,406
Ensembl chr 4:110,720,100...110,789,702
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    response to stimulus 8966
      response to endogenous stimulus 1921
        response to nerve growth factor 83
          cellular response to nerve growth factor stimulus + 79
Path 2
Term Annotations click to browse term
  biological_process 16524
    response to stimulus 8966
      response to chemical 5474
        response to organic substance 3519
          response to growth factor 783
            response to nerve growth factor 83
              cellular response to nerve growth factor stimulus + 79
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.