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ONTOLOGY REPORT - ANNOTATIONS


Term:intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
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Accession:GO:1990127 term browser browse the term
Definition:A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.


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negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G Bdkrb2 bradykinin receptor B2 JBrowse link 6 129,399,468 129,429,676 RGD:1624291
RGD:1600115

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 19578
    response to stimulus 10490
      response to stress 3960
        response to osmotic stress 127
          cellular response to osmotic stress 63
            intrinsic apoptotic signaling pathway in response to osmotic stress 9
              intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
Path 2
Term Annotations click to browse term
  biological_process 19578
    biological regulation 13539
      regulation of biological process 12843
        regulation of cellular process 12334
          signal transduction 6929
            apoptotic signaling pathway 629
              intrinsic apoptotic signaling pathway 301
                intrinsic apoptotic signaling pathway in response to osmotic stress 9
                  intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                    regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.