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ONTOLOGY REPORT - ANNOTATIONS


Term:intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
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Accession:GO:1990127 term browser browse the term
Definition:A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.


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negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDKRB2 bradykinin receptor B2 ISO (MGI:MGI:3654719|PMID:16571598) MGI PMID:16571598 MGI:MGI:3654719 NCBI chr14:76,832,833...76,873,860
Ensembl chr14:96,156,494...96,196,253
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Path 1
Term Annotations click to browse term
  biological_process 12524
    response to stimulus 6721
      response to stress 3229
        response to osmotic stress 109
          cellular response to osmotic stress 47
            intrinsic apoptotic signaling pathway in response to osmotic stress 9
              intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
Path 2
Term Annotations click to browse term
  biological_process 12524
    biological regulation 9129
      regulation of biological process 8652
        regulation of cellular process 8181
          signal transduction 3809
            apoptotic signaling pathway 600
              intrinsic apoptotic signaling pathway 294
                intrinsic apoptotic signaling pathway in response to osmotic stress 9
                  intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                    regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.