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ONTOLOGY REPORT - ANNOTATIONS


Term:intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
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Accession:GO:1990127 term browser browse the term
Definition:A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.


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negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDKRB2 bradykinin receptor B2 IEA Ensembl GO_REF:0000107 NCBI chr14:96,204,839...96,244,164
Ensembl chr14:96,204,679...96,244,166
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 18650
    response to stimulus 10129
      response to stress 4574
        response to osmotic stress 132
          cellular response to osmotic stress 64
            intrinsic apoptotic signaling pathway in response to osmotic stress 9
              intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
Path 2
Term Annotations click to browse term
  biological_process 18650
    biological regulation 13283
      regulation of biological process 12625
        regulation of cellular process 12020
          signal transduction 6562
            apoptotic signaling pathway 674
              intrinsic apoptotic signaling pathway 323
                intrinsic apoptotic signaling pathway in response to osmotic stress 9
                  intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                    regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.