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ONTOLOGY REPORT - ANNOTATIONS


Term:intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator
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Accession:GO:1990127 term browser browse the term
Definition:A series of molecular signals in which an intracellular signal is conveyed to trigger the apoptotic death of a cell. The pathway is induced by the cell cycle regulator phosphoprotein p53, or an equivalent protein, in response to the detection of osmotic stress, and ends when the execution phase of apoptosis is triggered.


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negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G BDKRB2 bradykinin receptor B2 IEA Ensembl GO_REF:0000107 NCBI chr 7:117,438,622...117,472,005
Ensembl chr 7:117,438,543...117,472,003
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Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 16524
    response to stimulus 8965
      response to stress 3628
        response to osmotic stress 122
          cellular response to osmotic stress 60
            intrinsic apoptotic signaling pathway in response to osmotic stress 9
              intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
Path 2
Term Annotations click to browse term
  biological_process 16524
    biological regulation 11991
      regulation of biological process 11411
        regulation of cellular process 10961
          signal transduction 5920
            apoptotic signaling pathway 610
              intrinsic apoptotic signaling pathway 298
                intrinsic apoptotic signaling pathway in response to osmotic stress 9
                  intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    negative regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 1
                    positive regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator 0
                    regulation of intrinsic apoptotic signaling pathway in response to osmotic stress by p53 class mediator + 1
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.