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ONTOLOGY REPORT - ANNOTATIONS


Term:exosomal secretion
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Accession:GO:1990182 term browser browse the term
Definition:The process whereby a membrane-bounded vesicle is released into the extracellular region by fusion of the limiting endosomal membrane of a multivesicular body with the plasma membrane.
Synonyms:exact_synonym: exosomal secretory pathway;   extracellular vesicular exosome secretion;   multi-vesicular body fusion with plasma membrane;   secretion of exosome
 narrow_synonym: exosomal protein secretion


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exosomal secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G COPS5 COP9 signalosome subunit 5 JBrowse link 4 67,740,528 67,758,153 RGD:14298760
G RAB11A RAB11A, member RAS oncogene family JBrowse link 1 163,858,254 163,887,741 RGD:14298760
G RAB27A RAB27A, member RAS oncogene family JBrowse link 1 116,532,816 116,606,477 RGD:14298760
negative regulation of exosomal secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G RAB7A RAB7A, member RAS oncogene family JBrowse link 13 71,777,422 71,886,758 RGD:14298760
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 1 158,233,039 158,273,533 RGD:14298760
positive regulation of exosomal secretion term browser
Symbol Object Name JBrowse Chr Start Stop Reference
G ATP13A2 ATPase cation transporting 13A2 JBrowse link 6 75,618,317 75,638,591 RGD:14298760
G CHMP2A charged multivesicular body protein 2A JBrowse link 6 63,102,155 63,105,032 RGD:14298760
G RAB7A RAB7A, member RAS oncogene family JBrowse link 13 71,777,422 71,886,758 RGD:14298760
G SDC1 syndecan 1 JBrowse link 3 117,987,585 118,011,886 RGD:14298760
G SNF8 SNF8 subunit of ESCRT-II JBrowse link 12 25,142,748 25,152,847 RGD:14298760
G VPS4B vacuolar protein sorting 4 homolog B JBrowse link 1 158,233,039 158,273,533 RGD:14298760

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 15257
    cellular process 13567
      export from cell 703
        secretion by cell 671
          exocytosis 249
            exosomal secretion 9
              multivesicular body fusion to apical plasma membrane 0
              negative regulation of exosomal secretion 2
              positive regulation of exosomal secretion 6
              regulation of exosomal secretion + 6
Path 2
Term Annotations click to browse term
  biological_process 15257
    localization 4701
      establishment of localization 3574
        transport 3467
          export from cell 703
            secretion by cell 671
              exocytosis 249
                exosomal secretion 9
                  multivesicular body fusion to apical plasma membrane 0
                  negative regulation of exosomal secretion 2
                  positive regulation of exosomal secretion 6
                  regulation of exosomal secretion + 6
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.