Submit Data |  Help |  Video Tutorials |  News |  Publications |  FTP Download |  REST API |  Citing RGD |  Contact   

ONTOLOGY REPORT - ANNOTATIONS


Term:mitotic checkpoint complex, CDC20-MAD2 subcomplex
go back to main search page
Accession:GO:1990333 term browser browse the term
Definition:A protein complex involved in the spindle checkpoint, preventing the activation of the anaphase-promoting complex until all chromosomes are correctly attached in a bipolar fashion to the mitotic spindle. In budding yeast this complex consists of Mad2p and Cdc20p, and in mammalian cells it consists of MAD2 and CDC20.
Comment:An example of this is cdc20 in Saccharomyces cerevisiae (P26309) in PMID:15879521 (inferred from direct assay).
Synonyms:exact_synonym: CDC20-MAD2 complex
 xref: IntAct:EBI-1270646


show annotations for term's descendants       view all columns           Sort by:
 

Term paths to the root
Path 1
Term Annotations click to browse term
  cellular_component 19951
    protein-containing complex 5828
      mitotic checkpoint complex, CDC20-MAD2 subcomplex 0
Path 2
Term Annotations click to browse term
  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        intracellular organelle 12137
          intracellular membrane-bounded organelle 10066
            nucleus 6843
              mitotic checkpoint complex 1
                mitotic checkpoint complex, CDC20-MAD2 subcomplex 0
paths to the root

NHLBI Logo

RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.