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ONTOLOGY REPORT - ANNOTATIONS


Term:CUE1-UBC7 ubiquitin-conjugating enzyme complex
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Accession:GO:1990389 term browser browse the term
Definition:A protein complex capable of ubiquitin-conjugating enzyme activity during ER-associated protein degradation (ERAD). In S. cerevisiae, UBC7 is the ubiquitin-conjugating enzyme (E2) and requires binding to the ER surface by CUE1.
Comment:An example of this is UBC7 in Saccharomyces cerevisiae (Q02159) in PMID:16179953 (inferred from direct assay).
Synonyms:exact_synonym: CUE1-UBC7 ubiquitin-conjugating enzyme (E2)
 xref: IntAct:EBI-9207004


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  cellular_component 19951
    intracellular 13934
      ubiquitin conjugating enzyme complex 8
        CUE1-UBC7 ubiquitin-conjugating enzyme complex 0
Path 2
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  cellular_component 19951
    cellular anatomical entity 19598
      organelle 12670
        membrane-bounded organelle 10978
          organelle membrane 2715
            endoplasmic reticulum membrane 874
              ER ubiquitin ligase complex 8
                CUE1-UBC7 ubiquitin-conjugating enzyme complex 0
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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.