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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
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Accession:GO:1990440 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
Synonyms:exact_synonym: activation of transcription from RNA polymerase II promoter in response to ER stress;   stimulation of transcription from RNA polymerase II promoter in response to ER stress;   up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;   upregulation of Pol II transcription induced by ER stress;   upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
 broad_synonym: ER stress-induced upregulation of transcription;   up-regulation of transcription induced by ER stress


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positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G Atf3 activating transcription factor 3 ISO (PMID:24939851) RGD PMID:24939851 NCBI chr13:109,817,892...109,849,632
Ensembl chr13:109,817,728...109,849,632
JBrowse link
G Atf4 activating transcription factor 4 ISO
IBA
(PMID:12871976), (PMID:21113145)
PMID:21873635
(MGI:MGI:5433837|PMID:21113145), (MGI:MGI:5613480|PMID:12871976)
RGD PMID:12871976, PMID:21113145, PMID:21873635 MGI:MGI:5433837, MGI:MGI:5613480, RGD:13792537 NCBI chr 7:121,480,723...121,482,781
Ensembl chr 7:121,480,723...121,482,772
JBrowse link
G Atf6 activating transcription factor 6 ISO (PMID:11163209), (PMID:11256944), (PMID:16469704) RGD PMID:11163209, PMID:11256944, PMID:16469704 NCBI chr13:89,053,457...89,242,531
Ensembl chr13:89,055,983...89,242,443
JBrowse link
G Atf6b activating transcription factor 6 beta ISO (PMID:11256944) RGD PMID:11256944 NCBI chr20:4,414,283...4,422,283
Ensembl chr20:4,414,276...4,422,283
JBrowse link
G Cebpb CCAAT/enhancer binding protein beta ISO (PMID:15775988) RGD PMID:15775988 NCBI chr 3:164,424,502...164,425,933
Ensembl chr 3:164,424,515...164,425,910
JBrowse link
G Creb3l1 cAMP responsive element binding protein 3-like 1 IMP
ISO
PMID:15665855
(MGI:MGI:5616321|PMID:15665855)
RGD PMID:15665855, PMID:15665855 MGI:MGI:5616321, RGD:1558627 NCBI chr 3:80,892,433...80,933,283
Ensembl chr 3:80,892,435...80,933,283
JBrowse link
G Creb3l3 cAMP responsive element binding protein 3-like 3 ISO (PMID:16469704)
(MGI:MGI:5616319|PMID:16469704)
RGD PMID:16469704 MGI:MGI:5616319 NCBI chr 7:11,490,852...11,499,287
Ensembl chr 7:11,490,852...11,499,282
JBrowse link
G Ddit3 DNA-damage inducible transcript 3 IDA
IBA
ISO
IEA
PMID:8657121
PMID:21873635
UniProtKB:P17676 (PMID:15322075), (PMID:15775988), (PMID:22761832), (PMID:24939851)
GO_REF:0000107
(MGI:MGI:3525819|PMID:15601821)
RGD
Ensembl
PMID:15322075, PMID:15601821, PMID:15775988, PMID:22761832, PMID:24939851, PMID:8657121, PMID:21873635 GO_REF:0000107, MGI:MGI:3525819, RGD:1599740, RGD:13792537 NCBI chr 7:70,578,564...70,585,074
Ensembl chr 7:70,580,198...70,585,084
JBrowse link
G Eif2ak3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) RGD PMID:14729979 MGI:MGI:3722921 NCBI chr 4:98,648,513...98,709,695
Ensembl chr 4:98,648,545...98,709,694
JBrowse link
G Mbtps2 membrane-bound transcription factor peptidase, site 2 ISO
IBA
UniProtKB:O54862 (PMID:11163209)
PMID:21873635
RGD PMID:11163209, PMID:21873635 RGD:13792537 NCBI chr  X:40,258,933...40,309,047
Ensembl chr  X:40,258,493...40,310,563
JBrowse link
G Tp53 tumor protein p53 ISO (MGI:MGI:5621265|PMID:16407291) RGD PMID:16407291 MGI:MGI:5621265 NCBI chr10:56,186,299...56,198,449
Ensembl chr10:56,187,020...56,198,449
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 20028
    response to stimulus 10583
      response to stress 4063
        cellular response to stress 1981
          response to endoplasmic reticulum stress 261
            positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 11
Path 2
Term Annotations click to browse term
  biological_process 20028
    metabolic process 12271
      cellular metabolic process 11085
        cellular aromatic compound metabolic process 5715
          nucleobase-containing compound metabolic process 5489
            nucleic acid metabolic process 4985
              RNA metabolic process 4469
                RNA biosynthetic process 3477
                  regulation of RNA biosynthetic process 3341
                    regulation of nucleic acid-templated transcription 3336
                      regulation of transcription, DNA-templated 3287
                        positive regulation of transcription, DNA-templated 1696
                          positive regulation of transcription by RNA polymerase II 1392
                            positive regulation of transcription from RNA polymerase II promoter in response to stress 25
                              positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.