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ONTOLOGY REPORT - ANNOTATIONS


Term:positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
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Accession:GO:1990440 term browser browse the term
Definition:Any process that activates or increases the frequency, rate or extent of transcription from an RNA polymerase II promoter as a result of an endoplasmic reticulum stress.
Synonyms:exact_synonym: activation of transcription from RNA polymerase II promoter in response to ER stress;   stimulation of transcription from RNA polymerase II promoter in response to ER stress;   up-regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress;   upregulation of Pol II transcription induced by ER stress;   upregulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress
 broad_synonym: ER stress-induced upregulation of transcription;   up-regulation of transcription induced by ER stress


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positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress term browser
Symbol Object Name Evidence Notes Source PubMed Reference(s) RGD Reference(s) Position
G ATF3 activating transcription factor 3 ISO (PMID:24939851) ParkinsonsUK-UCL PMID:24939851 NCBI chr 1:188,176,728...188,188,842
Ensembl chr 1:193,036,793...193,049,150
JBrowse link
G ATF4 activating transcription factor 4 ISO (MGI:MGI:5433837|PMID:21113145), (MGI:MGI:5613480|PMID:12871976)
(PMID:21113145)
(PMID:12871976)
ParkinsonsUK-UCL PMID:12871976, PMID:21113145 MGI:MGI:5433837, MGI:MGI:5613480 NCBI chr22:20,426,743...20,428,892
Ensembl chr22:38,248,094...38,249,249
JBrowse link
G ATF6 activating transcription factor 6 ISO (PMID:11163209), (PMID:11256944), (PMID:16469704) ParkinsonsUK-UCL PMID:11163209, PMID:11256944, PMID:16469704 NCBI chr 1:137,178,629...137,382,256
Ensembl chr 1:140,977,750...141,176,725
JBrowse link
G ATF6B activating transcription factor 6 beta ISO (PMID:11256944) ParkinsonsUK-UCL PMID:11256944 NCBI chr 6:31,762,161...31,775,136
Ensembl chr 6:32,643,124...32,655,617
JBrowse link
G CEBPB CCAAT enhancer binding protein beta ISO (PMID:15775988) ParkinsonsUK-UCL PMID:15775988 NCBI chr20:46,533,163...46,535,282 JBrowse link
G CREB3L1 cAMP responsive element binding protein 3 like 1 ISO (MGI:MGI:5616321|PMID:15665855) ParkinsonsUK-UCL PMID:15665855 MGI:MGI:5616321, RGD:1558627 NCBI chr11:46,236,384...46,280,145
Ensembl chr11:46,788,561...46,830,246
JBrowse link
G CREB3L3 cAMP responsive element binding protein 3 like 3 ISO (PMID:16469704)
(MGI:MGI:5616319|PMID:16469704)
ParkinsonsUK-UCL PMID:16469704 MGI:MGI:5616319 NCBI chr19:3,176,863...3,194,294
Ensembl chr19:4,127,597...4,144,300
JBrowse link
G DDIT3 DNA damage inducible transcript 3 ISO PMID:8657121
(PMID:15775988)
(MGI:MGI:3525819|PMID:15601821)
(PMID:22761832)
(PMID:15322075), (PMID:24939851)
ParkinsonsUK-UCL PMID:8657121, PMID:15322075, PMID:15601821, PMID:15775988, PMID:22761832, PMID:24939851 MGI:MGI:3525819, RGD:1599740 NCBI chr12:31,406,332...31,410,293
Ensembl chr12:31,664,743...31,668,701
JBrowse link
G EIF2AK3 eukaryotic translation initiation factor 2 alpha kinase 3 ISO (MGI:MGI:3722921|PMID:14729979) ParkinsonsUK-UCL PMID:14729979 MGI:MGI:3722921 NCBI chr2A:87,688,732...87,759,580
Ensembl chr2A:89,596,833...89,667,468
JBrowse link
G MBTPS2 membrane bound transcription factor peptidase, site 2 ISO (PMID:11163209) ParkinsonsUK-UCL PMID:11163209 NCBI chr  X:14,470,268...14,529,854
Ensembl chr  X:21,825,780...21,883,550
JBrowse link
G TP53 tumor protein p53 ISO (MGI:MGI:5621265|PMID:16407291) ParkinsonsUK-UCL PMID:16407291 MGI:MGI:5621265 NCBI chr17:7,699,449...7,717,812
Ensembl chr17:7,684,922...7,706,120
JBrowse link

Term paths to the root
Path 1
Term Annotations click to browse term
  biological_process 12561
    response to stimulus 6736
      response to stress 3232
        cellular response to stress 1692
          response to endoplasmic reticulum stress 226
            positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 11
Path 2
Term Annotations click to browse term
  biological_process 12561
    metabolic process 7977
      cellular metabolic process 7333
        cellular aromatic compound metabolic process 3878
          nucleobase-containing compound metabolic process 3701
            nucleic acid metabolic process 3398
              RNA metabolic process 3010
                RNA biosynthetic process 2446
                  regulation of RNA biosynthetic process 2368
                    regulation of nucleic acid-templated transcription 2363
                      regulation of transcription, DNA-templated 2355
                        positive regulation of transcription, DNA-templated 1422
                          positive regulation of transcription by RNA polymerase II 1139
                            positive regulation of transcription from RNA polymerase II promoter in response to stress 25
                              positive regulation of transcription from RNA polymerase II promoter in response to endoplasmic reticulum stress 11
paths to the root

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RGD is funded by grant HL64541 from the National Heart, Lung, and Blood Institute on behalf of the NIH.